Unintelligent Design - Another Failure By Creationism's Blundering Designer

Machine for repairing broken mtDNA.

AI-Generated image
(with apologies to William Heath Robinson)

The graphic shows images of a cell under mtDNA replication stress made using so-called Correlative Light and Electron Microscopy (for short: CLEM). The mitochondrial DNA (mtDNA, green) is ejected from the mitochondria (magenta) and taken up by a lysosome, which contains the retromer (cyan). The highlighted section was also analysed using 3D-CLEM to obtain volumetric information.

Fig.: HHU/David Pla-Martín.

Medicine: Publication in Science Advances

Yet Another Workaround for a Flawed Design.

Researchers led by Professor Dr David Pla-Martín of Heinrich Heine University Düsseldorf, alongside colleagues from the University of Cologne, have uncovered yet another complex but error-prone workaround—this time, to fix a problem that stems from an earlier design flaw.

They have identified a mechanism used to repair mitochondrial DNA (mtDNA) when it breaks. From an intelligent design perspective, mitochondria — once free-living bacteria—were supposedly the 'quick fix' to give eukaryotic cells the ability to efficiently convert glucose into adenosine triphosphate (ATP) using oxygen. ATP is the primary energy currency used in metabolic reactions, formed from adenosine diphosphate (ADP) and phosphate.

A truly intelligent designer, however, could have simply endowed cells with this biochemical machinery from the start—no need to incorporate foreign bacteria complete with their own DNA. But apparently, that would have been too simple.

This convoluted solution, predictably, comes with problems. Mitochondria often replicate their DNA imperfectly, or the DNA becomes damaged, leading to mitochondrial failure and a range of diseases. So, yet another layer of biological complexity has evolved to patch up the broken mtDNA. And, in classic Heath Robinson fashion, this repair mechanism is itself error-prone.

Refuting Creationism - The Long Pre-'Creation Week' Evolutionary History of Bacteria

The Great Oxidation Event

AI-Generated Image (ChatGPT4o)

Machine learning helps construct an evolutionary timeline of bacteria - UQ News - The University of Queensland, Australia

A helpful analogy employed by Richard Dawkins in Unweaving the Rainbow illustrates the vastness of evolutionary time:

Fling your arms wide in an expansive gesture to span all of evolution from its origins at your left fingertip to today at your right fingertip. All the way across your midline to well past your right shoulder, life consisted of nothing but bacteria. Multi-celled invertebrate life flowers somewhere around your right elbow. The dinosaurs originate in the middle of your right palm and go extinct around your last finger joint. The whole story of Homo sapiens and our predecessor Homo erectus is contained in the thickness of one nail-clipping.

We can construct such a timeline because, although microbial life leaves few conventional fossils, it does leave behind chemical signatures in ancient rocks—clues to how bacteria lived, metabolised, and evolved.

By correlating this geochemical record with genomic data, a multinational collaboration – led by researchers from the Okinawa Institute of Science and Technology, Japan, the University of Bristol, UK, Queensland University of Technology, Australia and the University of Queensland, Australia, has used machine learning to reconstructed an evolutionary tree of bacterial lineages. This allows us to trace how different taxa adapted to major environmental changes, such as the Great Oxidation Event (GOE). Remarkably, this study suggest that some microbes had already evolved the capacity to utilise oxygen even before it became abundant during the GOE.

The disturbing fact for creationists is not the evidence of common origins and descent with modification that this study reveals, but the fact that it all happened billions of years before their mythical 'Creation Week' when their god allegedly created a small flat planet with a dome over it in the Middle East. But then this is hardly surprising, since 99.9975% of the history of life on Earth happened before that alleged act of magic.

How the team of scientists conducted this study, and their conclusions are the subject of a research paper in Science and a news item from the University of Queensland, Australia:

Refuting Creationsm - Evolution By Loss of Genes, Horizontal Gene Transfer And Gene Duplication

Nitzschia sp

By Kristian Peters - Own work,
CC BY-SA 3.0,
Wikimedia

This article is best read on a laptop, desktop, or tablet

Nitzschia sing1 lives on the alginate in the cell walls of decaying brown algae.

A borrowed bacterial gene allowed some marine diatoms to live on a seaweed diet | PRESS-NEWS.org

A fundamental axiom of creationism is the claim that any loss of genetic information is invariably detrimental—so much so that any mutation resulting in such a loss would be fatal and could therefore play no role in evolution. A second axiom asserts that new genetic information cannot arise naturally and must instead be supplied by a supernatural intelligent designer.

Both of these assertions are demonstrably false. Nevertheless, they continue to feature in creationist apologetics, relying on the audience's ignorance and incredulity to pass as justification for belief in an intelligent creator.

To add further difficulty for creationist claims, scientists have now identified a marine diatom, Nitzschia sing1, that has not only lost the genes and organelles required for photosynthesis — present in its photosynthetic relatives — but has also adapted successfully without them. It achieved this by acquiring new genetic information through horizontal gene transfer from a marine bacterium. The transferred gene subsequently underwent extensive duplication and diversification into three gene families, each with complementary functions. Together, these 91 versions of the acquired gene enable N. sing1 to metabolise alginate, a carbohydrate found in the cell walls of brown algae such as kelp.

Unintelligent Design - Why Humans Are Not Intelligently Designed for Modern life

"Now look what you've done! The place is not fit to live in anymore!"

Humanity's Real Problem: Accelerating Evolutionary Mismatch | Psychology Today

A sure sign of unintelligent design is one that completely fails to anticipate the future. Biologically speaking, poor design occurs when an organism is adapted to an environment at a specific moment but becomes increasingly maladapted as the environment evolves. This happens either because the organism fails to adapt quickly enough or because it was never designed with future changes in mind in the first place.

A good, intelligent designer, especially one equipped with the power of foresight, would not just design for today but for tomorrow, next year and for the foreseeable future. Failure to do so is incompetence, indolence or sheer malevolence in putting its design on course for ultimate disaster.

In my book, The Body of Evidence: How the Human Body Refutes Creationism, I highlight numerous examples where the human body evolved for past environments — previous diets, predators, and social pressures — leaving us today with various vulnerabilities and compromises.

Human evolution moves at a glacial pace, barely noticeable even over many generations, while our environment has dramatically transformed within just a few decades.

Consider the technology available to our parents and grandparents compared to what we now take for granted—steam trains, landline telephones, no internet or colour TV, no central heating or air conditioning beyond an open fire or window, no satellite navigation, and no instant global communication. Further back, major societal shifts arose from mechanised farming, factory work, innovations in textile manufacturing, and even improvements in wheat milling for bread. Later still came automobiles and mass transit.

Yet, genetically speaking, our recent ancestors who navigated these revolutionary changes remain nearly identical to us today.

Now, we stand on the threshold of another seismic shift: artificial intelligence. Just a decade ago, writing this introduction would have involved considerable time researching, fact-checking, and carefully drafting paragraphs that still might not have fully conveyed my intended message. Today, I can draft my thoughts, then leverage the vast processing power of AI (like ChatGPT-4.5) to refine and clarify my ideas effortlessly. These introductory paragraphs are precisely the outcome of such a collaboration.

The core issue, however, remains that human culture is evolving at a rate several orders of magnitude faster than our biological capacity to adapt, creating an ever-widening gap between how we need to respond to new challenges and how we're inherently equipped to do so.

The consequences of this accelerating mismatch are thoughtfully explored in an article by Mike Brooks, Ph.D., in Psychology Today, Humanity's Real Problem: Accelerating Evolutionary Mismatch.

Refuting Creationism - People Of the Green Sahara - No Flood Noticed

View of the Takarkori rock shelter in Southern Libya.

© Archaeological Mission in the Sahara,
Sapienza University of Rome

View from the Takarkori rock shelter in Southern Libya.

© Archaeological Mission in the Sahara,
Sapienza University of Rome.

First ancient genomes from the Green Sahara deciphered

According to literal interpretations of biblical creationism, the first two humans were created approximately 6,000 years ago without any ancestors. Subsequently, around 4,000 years ago, the Earth was supposedly submerged by a global flood. According to this narrative, all present-day humans descended from the eight survivors who endured a year-long voyage in a large vessel accompanied by two (or, in some accounts, seven) individuals of each animal species. After the flood receded, these survivors are said to have repopulated a barren and sterile world in which all previously existing life had been destroyed.

In contrast, scientific evidence indicates that more than 7,000 years ago, human populations inhabited a Sahara region that was markedly different from today's desert. At the time, a wetter climate supported forests, grasslands, lakes, and rivers. These Saharan people were only distantly related to other non-African populations, as they had diverged from East and South African Homo sapiens around the same period—approximately 50,000 years ago—that modern non-African populations migrated out of Africa into Eurasia. Subsequently, the Saharan population remained largely isolated from both sub-Saharan African and Eurasian populations.

The critical distinction between these two accounts lies in their evidence base. Creationism relies solely on written narratives from a text of uncertain historical authenticity, whereas science relies upon verifiable, physical evidence, in this case DNA extracted from two mummified Saharan individuals discovered in Algeria.

This fundamental difference exemplifies the contrast between religion and science: religion typically relies on tradition, superstition, and narratives lacking empirical support, whereas science is grounded in observable evidence and logical deduction.

The evidence for the existence and origin of this Saharan population comes from the work of researchers at the Dept. of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. It's significance is that it argues against the green Sahara being one of the migration routes for modern humans out of Africa and a return migration back into Africa because the Saharan population were genetically distinct and have a very low level of Neanderthal DNA unlike the western Eurasian Homo sapiens.

The findings of the group are published open access in Nature. The research is described in a Max Planck Institute News release:

Malevolent Designer News - How Monkeypox Is Being Redesigned to Infect More People

Mpox could become a serious global threat, scientists warn | University of Surrey

Science has just dealt creationism another body blow.

Researchers from the University of Surrey, UK, have demonstrated that the monkeypox virus has undergone a mutation that enhances its ability to spread more readily from person to person through direct contact. This increased transmissibility raises the concern of a potential global pandemic.

Since this mutation confers a benefit to the virus, it aligns with William A. Dembski's concept of 'specified complexity', which he uses to argue for intelligent design. By extension, Dembski’s argument suggests evidence of an intelligent designer, whom his intended audience typically identifies as the Christian God.

However, because the mutation has resulted in a greater prevalence of the mutated form of the virus compared to non-mutated forms, this clearly demonstrates evolution through natural selection. Consequently, it contradicts the notion of 'devolution' proposed by Michael J. Behe, who suggests that parasites and pathogens represent biological deterioration rather than adaptive evolution.

Therefore, the new variant of the monkeypox virus presents either evidence supporting creationism's deity — which would imply intentional creation of viruses specifically designed to cause illness—or clear evidence supporting evolution through natural selection.

Unintelligent Design - The Heath-Robinson Machine That Keeps Rogue DNA Under Control

How a critical enzyme keeps potentially dangerous genes in check – lji.org

The human body, like those of most multicellular organisms, exhibits numerous instances of suboptimal design. These imperfections arise from evolutionary processes that balance competing demands, often prioritizing immediate reproductive success over long-term well-being and efficiency. As a result, many biological structures and functions are prone to errors, which tend to accumulate and manifest more prominently with age.

These inherent imperfections have driven the evolution of additional layers of complexity aimed at mitigating potential failures. Such complexity would likely be unnecessary if these biological systems had been optimally designed from the outset. Therefore, the presence of intricate mechanisms to counteract inherent errors serves as compelling evidence for evolution and challenges the notion of intelligent design. Examples of these compensatory complexities are abundant across all multicellular organisms.

A pertinent example involves the regulation of transposable elements (TEs), often referred to as "jumping genes." These DNA sequences can move within the genome, potentially causing significant disruptions if not properly controlled. In healthy cells, TEs are kept in check within heterochromatin — a tightly packed form of DNA that serves as a "prison" for these elements. Recent research led by Professor Anjana Rao, Ph.D., at the La Jolla Institute for Immunology, published in Nature Structural & Molecular Biology, has shed light on this control mechanism. The study reveals that the enzyme O-GlcNAc transferase (OGT) plays a crucial role in suppressing TE activity by restraining TET enzymes, thereby maintaining genomic stability.

This intricate system of checks and balances underscores the evolutionary arms race within our genomes, highlighting the complexity that arises from natural selection's ongoing efforts to mitigate the potential harms posed by transposable elements.

Refuting Creationism - Stone Tool Manufacture in China, 40-50,000 Before 'Creation Week'.

Quina technology was found in Europe decades ago but has never before been found in East Asia.

Ben Marwick

Discovery of Quina technology challenges view of ancient human development in East Asia | UW News

What may present a fascinating puzzle for science often deals a fatal blow to creationism — if only its adherents would acknowledge it. However, creationism remains a "brain-dead zombie", artificially kept alive by the manoeuvres of creationist leaders whose power and income rely upon it.

For instance, the recent discovery in China of stone tools exhibiting 'Quina technology', typically associated with Neanderthals, raises intriguing questions for archaeologists and anthropologists. Neanderthals were previously thought to have inhabited primarily western Eurasia, yet these Chinese artefacts, dated to between 50,000 and 60,000 years ago, suggest their influence or presence extended much farther east than previously known. These findings pose fascinating questions regarding ancient human migration and technological exchange.

However, these same discoveries directly contradict creationist beliefs that the Earth is merely 6,000 to 10,000 years old and that humans appeared through a special creation without ancestral links. While science thrives on unanswered questions and continuously adapts its theories based on new evidence, creationism relies rigidly on dogma. When its foundational claims are refuted, the entire belief system crumbles. Religion insists upon unreasonable certainty, whereas science flourishes through reasonable uncertainty.

The discovery of this evidence of Quina Technology was made at the Longtan archaeological site in southwest China by an international group of archaeologists, which included Professor Ben Marwick of Washington University, USA. It is first such discovery in Asia of a technology known to have existed in Middle Palaeolothic Europe and associated there with Neanderthals.

The question is, does this show that Neanderthals were more widespread than we thought, or has their technology been shared with other hominins such as the Denisovans? Or did the same technology arise independently in China?