Genetic variants for skin color in African Americans linked to vitamin D deficiency, City of Hope study finds
Here is a nice piece of science for people who have fallen for the Intelligent [sic] Design hoax to ponder on. It begs the question, Is God a malevolent Racist?
It is a paper by researchers at Beckman Research Institute of City of Hope, showing the link between skin colour in African Americans and the problems associated with the resultant vitamin D deficiency that 70% of them suffer from - an increased risk for cancers and cardiovascular diseases. African Americans have a 14% greater risk from cancers than do white Americans.
First, a little background information, from a blog post I wrote some years ago:
Religion, Creationism, evolution, science and politics from a centre-left atheist humanist. The blog religious frauds tell lies about.
Saturday, 20 February 2021
Evolution News - Evolution Before Abiogenesis

Fig. 1.
Templated ligation of random sequence DNA 12-mers. (A) Before cells evolved, the first ribozymes were thought to perform basic cell functions. In the exponentially vast sequence space, spontaneous emergence of a functional ribozyme is highly unlikely, therefore preselection mechanisms were likely necessary. (B) In our experiment, DNA strands hybridize at low temperatures to form three-dimensional complexes that can be ligated and preserved in the high temperature dissociation steps. The system self-selects for sequences with specific ligation site motifs as well as for strands that continue acting as templates. Hairpin sequences are therefore suppressed. (C) Concentration analysis shows progressively longer strands emerging after multiple temperature cycles. The inset (A-red, T-blue) shows that, although 12-mers (88,009 strands) have essentially random sequences (white), various sequence patterns emerge in longer strands (60-mers, 235,913 strands analyzed). (D) Samples subjected to different number (0 to 1,000) of temperature cycles between 75 °C and 33 °C. Concentration quantification is done on PAGE with SYBR poststained DNA.
News today that research physicists at Ludwig-Maximilians-Universität, München, Germany (LMU) may have solved one of the key questions relating to abiogenesis - how did order begin to emerge from the chaos of random organic chemicals? It appears that this was the result of Darwinian evolution of molecules!
In the words of the LMU New release:
Before life emerged on Earth, many physicochemical processes on our planet were highly chaotic. A plethora of small compounds, and polymers of varying lengths, made up of subunits (such as the bases found in DNA and RNA), were present in every conceivable combination. Before life-like chemical processes could emerge, the level of chaos in these systems had to be reduced. In a new study, LMU physicists led by Dieter Braun show that basic features of simple polymers, together with certain aspects of the prebiotic environment, can give rise to selection processes that reduce disorder.In common with many researchers in this field, the LMU team placed abiogenesis in "narrow, water-filled chambers within porous volcanic rocks on the sea bottom", in other words in the porous rocks around deep ocean hydrothermal vents.
These studies showed that, in the presence of temperature differences and a convective phenomenon known as the Soret effect, RNA strands could locally be accumulated by several orders of magnitude in a length-dependent manner. “The problem is that the base sequences of the longer molecules that one obtains are totally chaotic“, says Braun. Evolved ribozymes (RNA-based enzymes) have a very specific base sequence that enable the molecules to fold into particular shapes, while the vast majority of oligomers formed on the Early Earth most probably had random sequences. “The total number of possible base sequences, known as the ‘sequence space’, is incredibly large,” says Patrick Kudella, first author of the new report. “This makes it practically impossible to assemble the complex structures characteristic of functional ribozymes or comparable molecules by a purely random process.” This led the LMU team to suspect that the extension of molecules to form larger ‘oligomers’ was subject to some sort of preselection mechanism.
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Friday, 19 February 2021
Termite Gut Microbes Could Aid Biofuel Production

Credit: ABS Natural History/Shutterstock.com
Termite gut microbes
Credit: mantismundi
Another example today of why maintaining biodiversity on Earth may be vitally important to ours and the planet's survival. A microbe in the gut of termites could hold the key to producing biofuels from sustainable plant sources.
Termites are incapable on their own of digesting cellulose and the other main structural material of the wood and tough plant matter they feed on - lignin. Instead, they are entirely dependent on a diverse population of bacteria and protozoa that live symbiotically in their gut and which do the digestion for them. Very many of these organisms are unique to the guts of termites.
Now scientists at Toulouse Biotechnology Institute, TBI, Université de Toulouse, France with colleagues from the Research Institute for Sustainable Humanosphere, Kyoto University, Japan, and the Laboratory of Food Chemistry, Wageningen University, The Netherlands, have shown that these organisms from the guts of four species of termite, Nasutitermes ephratae, N. lujae, Microcerotermes parvus, and Termes hospes, can turn wheat straw into a useable biofuel.
The findings were published a few days ago in the American Chemical Society's journal, ACS Sustainable Chemistry & Engineering, regrettably behind a firewall and the ACS refuse permission to reprint even the abstract, which can, be read here. However, the ACS News Service press release gives full details:
Evolution News - Reversal for Creationists

This dramatic paleoclimate change – which was hallmarked with widespread auroras – could help explain other evolutionary mysteries, like the extinction of Neandertals.
Photo: Unsplash.
One of the major problems Creationist frauds have to cope with is the regularity with which natural records contradict their preferred time-line. One such series of records is that of frequent geomagnetic reversals, when Earth's North and South magnetic poles flipped. These events are recorded in the magnetic alignment of particles in the mid-ocean ridges, which record the polarity of Earth at the moment they solidified from the magma welling up from the cracks in the mantle as the tectonic plates pull apart.
Another is in the indirect record in the amount of radiocarbon preserved in ancient tree rings, which increases at the point of reversal as Earth loses the protection from solar radiation provided by its magnetic field.
These records, of course, contradict Creationism's childish claims of a young Earth of just a few thousand years old. This one shows a magnetic reversal about 40,000 years ago - some 30,000 plus years before the Universe existed, according to Creationists.
Scientist from the University of New South Wales, Australia, have found evidence of a period of major climate change associated with the last geomagnetic reversal 42,000 years ago - when Earth's North and South magnetic poles changed places. This period, which they have called the ‘Adams Transitional Geomagnetic Event’, or ‘Adams Event’ for short, after Douglas Adams of 'Hitchhiker's Guide to the Galaxy' fame. Douglas Adam's famously said the answer to life the universe and everything was 42!
This magnetic reversal was a period of mass extinction that saw the demise of the Neanderthals. Evidence for this change was found in the remains of ancient New Zealand kauri trees which have been preserved in sediment for over 40,000 years.
As the UNSW press release explains:
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Thursday, 18 February 2021
Evolution News - The How and Why of Seahorse Evolution
How sessile seahorses managed to speciate and disperse across the world’s oceans | News and media | University of Konstanz
We have news today showing how the biological world we see now only makes sense in the context of the Theory of Evolution, and showing how well the TOE meshes with other strands of scientific evidence, in this case, genetics, plate techtonics and oceanography.
It was produced by an international research collaboration, involving a research team led by evolutionary biologist Professor Axel Meyer of the University of Konstanz, Germany and researchers from China and Singapore, which was able to identify factors that led to the success of the seahorse from a developmental biology perspective: its quickness to adapt by, for example, repeatedly evolving spines in the skin and its fast genetic rates of evolution.
Their results were published, open access, on 17 February 2021 in Nature Communications.
From the Konstanza Universität press release:
We have news today showing how the biological world we see now only makes sense in the context of the Theory of Evolution, and showing how well the TOE meshes with other strands of scientific evidence, in this case, genetics, plate techtonics and oceanography.
It was produced by an international research collaboration, involving a research team led by evolutionary biologist Professor Axel Meyer of the University of Konstanz, Germany and researchers from China and Singapore, which was able to identify factors that led to the success of the seahorse from a developmental biology perspective: its quickness to adapt by, for example, repeatedly evolving spines in the skin and its fast genetic rates of evolution.
Their results were published, open access, on 17 February 2021 in Nature Communications.
From the Konstanza Universität press release:
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Wednesday, 17 February 2021
How Science Works - Telling a Consistent Story of Crocodile Evolution

Image: José Avila-Cervantes.
Once in a while we get a piece of scientific research that shows how science, and the answers science provides, all mesh together to give a much larger picture, showing how several different branches of science all work to support one another and confirm our conclusions about what happened in the past to produce what we see today.
In this case, evidence from genetics, geology and climatology all work to explain what can be observed in the evolution of the American crocodiles either side of the Panamanian isthmus. It was provided by researchers from McGill University, Quebec, Canada who initially set out to see how far the Caribbean and Pacific populations of crocodiles had diverged from one another in the 3 million years since the Isthmus of Panama rose up and joined North and South America but separated the Atlantic and Pacific Oceans.
The news release from McGill University explains:
Evolution News - The Evolution of 'Selfish' Altruism
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Red paper wasp, Polistes canadensis Polistes colonies offer windows into the evolution of co-operation. Image: P Kennedy |
One of the things Creationists pretend to find hard to understand is how 'selfish' genes, or an evolutionary process that means individuals with certain beneficial mutations have an advantage over those who don't, can produce altruism. It probably tells us something about Creationists, that they don't understand how something which isn't purely selfish can improve the chances of survival of the species over all, or why this should be beneficial.
It may also help explain the recent finding that fundamentalist evangelical Christians tend to have a low regard for the health and welfare of others, as we are seeing by their selfish behaviour during the coronavirus pandemic.
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Evolution News - A Gift From Our Neanderthal Cousins

Readers may remember how, back last October, I reported on a paper from researchers at Karolinska Institutet and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, which showed that a gene carried on chromosome 3, which we inherited from our Neanderthal cousins, is a significant risk factor for severe Covid-19.
Now the same team have shown that Neanderthals also contributed a protective variant, carried on chromosome 12, that helps us fight RNA viruses. Genes known as OAS, from this region of chromosome 12, code for protein enzymes that break down viral RNA. People with this Neanderthal variant have a 20% lower chance of needing intensive care in hospital if they become infected with the SARS-CoV-2 coronavirus. This allele is present in half the non-African population of the world, showing in conveys a significant benefit and so has been steadily increasing in the human gene pool.
Tuesday, 16 February 2021
Trumpanzee News - How Trump Split the GOP
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QAnon conspiracy theorists in the failed coup d'etat |
Everything Donald J Trump does ends in failure. His businesses go bankrupt; his presidency was a monumental failure in which not a single one of his pre-election promises were kept and his handling of the coronavirus pandemic was probably the worst of any state, resulting in 25% of all cases world-wide being in America, peaking at 250,000 a day with 2,000 deaths, the measures scientists were urging to control it becoming political issues with widespread flouting of social distancing and mask-wearing and now deep suspicion about the safety and even the real purpose of the vaccine.
And now we discover that the party he led - the Republican Party of Lincoln - is deeply divided and practically in a state of civil war, as the evangelical Christian faction has become ever more extreme and mainstream, pushing the moderate Republicans out to the side-lines.
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Old Dead Gods - Stonehenge Rebuilt
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Stonehenge, Wiltshire, UK |
Stonehenge, that ancient monument in the middle of the Salisbury Plain in Wiltshire, England, may have been built first, about 5,000 years ago, in the Preseli Hills of South Wales, and then been dismantled, transported to its present site and re-erected. This is the conclusion of archaeologists from University College London (UCL) who have published a paper in the journal Antiquity.
The smaller, inner, stones or 'blue stones' are already known to have come from the Preseli Hills and to have been erected before the larger, outer ring of local 'sarsen' stones was erected. Now archaeologists led by Professor Mike Parker Pearson of the UCL Institute of Archaeology, have identified an ancient quarry and the remains of a stone circle nearby, which may have been dismantled and transported 140 miles away, possibly by migrants.
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Monday, 15 February 2021
Evolution News - On the Origin of Our Species

This cranium from Jebel Irhoud in Morocco is often called a modern human
ancestor. The meaning of that ancestry is discussed and disentangled in a
new study by Bergstrom and colleagues.
© Chris Stringer
As I have said before, despite Creationist fraudulent assertions that there are no transitional fossils in the human ancestral lineage, the reality is that there are, if anything too many of them. This has led to a confusing picture and a 'tree' more resembling of a bush than a neat tree with nicely spaced-out branches. But then nature has no obligation to provide us with neat, easy to understand data, especially when the reality is fuzzy and complicated.
Now a group of paleoanthropologists from the Natural History Museum, London, UKThe Francis Crick Institute, London, UK and the Max Planck Institute for the Science of Human History, Jena, Germany have joined forces to try to sort out the confusion and debunk a few misunderstanding that have arisen, even in scientific circles.
The Max Planck Institute news release explains:
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Christian Talibangelical Trumpanzees for Violence
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Attempted coup d’état by Trumpanzees, 6th January, 2021 |
In its American Perspective Survey, The Survey Center on American Life has revealed a post-Trump America deeply divided and with a large number of people, especially evangelical white Christians, ready to resort to violence to achieve their political ambitions.
But even as pride in America has taken a battering because of the antics of Trump and his supporters, the belief in American exceptionalism, that many of us non-Americans find so arrogant and worryingly nationalistic, still remains strong.
Although Trump retains considerable support, especially amongst the Republican rank and file, most Americas expressed relief that he had finally gone. There is also broad support for investigating the possible wrongdoings by his administration.
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Sunday, 14 February 2021
Creationist Failure News - Yes! It's Another of Those Commonplace 'Non-Existent' Things!
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Cantabrigiaster fezouataensis from the Lower Ordovician (Tremadocian) Fezouata Shale, Zagora Morocco Credit: Collection of Yale University |
Researchers from Cambridge University's Earth Sciences and Zoology Departments have identified an Ordovician period fossil, about about 450-million-years-old, from Morocco's Anti-Atlas Mountains as intermediate between the sea lilies or Crinoids and modern starfish. The Ordovician was a period of rapid diversification starting about 485.4 million years ago immediately after the Cambrian and lasting until about 443.8 million years ago.
Regular find like this must be acutely embarrassing for the Creationist frauds who tell their credulous dupes that the absence of these transitional forms in the fossil record means Darwin's TOE is falsified!
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Friday, 12 February 2021
Evolution News - How a Single Gene Alteration May Have Separated Modern Humans From Cousin Species
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Modern Human skull (L) compared to Neanderthal skull (R) |
Researchers at UC San Diego, led by Alysson R. Muotri, PhD, believe they have shown that a mutation in a single gene could have altered the way our ancestors' brains were wired, enabling them to develop complex social structures, language, adaptability, creativity and use of technology, all of which appear to have arisen over a very short period of time, by evolutionary standards.
The mutation involved a single base-pair substitution - the simplest of all mutations!
They did this by growing brain 'organoids' in Petri dishes from modified stem cells. The UC San Diego news release explains:
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Thursday, 11 February 2021
Trumpanzee Fruitloop News - "God Didn't Say Trump Lost, So He Won Really!"
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Amanda Grace, "All part of God's plan to make eveyone think Joe Biden won" |
Self-declared "prophetess" and Talibangelical grifter, Amanda Grace, normally bases her 'prophesies' on what the voices in her head say. This time, however, she's going with what they don't say.
In this case, despite wrongly telling her Trump would win last November, so far, 'God' hasn't told her Trump lost - so he must have won really and is still president! Or so she told a delighted right-wing author, commentator, and leading Trumpanzee cultist, Eric Metaxas, on The Eric Metaxas Radio Show.
Apparently believing that it's not the final tally of the votes cast, the certification of the count by state officials, the votes of the Electoral College and finally, certification of the result by Congress, that determines the outcome of American elections, but what her personal voices say, that determines them, she said:
There has been a delay for a reason. It’s not over, and it’s far from over with what the Lord is going to do with President Trump, what the Lord is going to do to the wicked of this nation, including the media. You know, I prophesied from the Lord in October about the media suffering the biggest crisis they ever had in 2021 for their crimes, so I’m watching for that to unfold.She also 'revealed' that it is all part of God's plan to make everyone think Joe Biden won, so there will be no doubt it is God's miracle when Trump is reinstalled in the White House.
But the real clincher is the fact that Trump is being impeached for a second time. Grace has declared, despite legal opinion to the contrary, that it is only possible to impeach a president in office, and not after he has been deposed, therefore, impeachment 'proves' he is still president, really:
There’s been a delay because I believe God is trying to get people’s eyes on him. He wants all eyes on him right now for the demonstration he’s going to put on. Just like when the Jews were at the Red Sea, and they’re there, and Egypt’s at their back, and it’s all eyes on God because either the Lord is going to do this, or it’s not going to happen. And when they thought there was a dead end, God saw a path through that water. So, God’s ways are much higher when he sees how to make a path when people don’t think there is a way.
The Lord has never said to me [Trump is] not going to serve a second term. Sometimes what the Lord doesn’t say is as important as what he says. And he never said to me, ‘President Trump is not going to serve a second term.’ However, I do believe, because I prophesied this last night from the Lord, a surprise is coming with this impeachment because you can’t impeach a citizen. So something is very interesting here going on, because they’re trying to impeach a citizen right now, if he really is a citizen. You can only impeach a sitting president, so this is like we have dueling presidents right now. This is what it is: dueling presidents.
People’s actions speak louder than their words. These wicked peole right now in Congress—who the Lord is going to deal severely with, by the way—you can only impeach a president. If he is really a citizen right now, how are you impeaching him? You can’t impeach a regular citizen. It’s not possible, not according to the law, not according to the Constitution. So their action—sometimes the actions of the wicked will give them away—are pointing that something is not quite kosher going on with who’s the president.
You actually can impeach a former President, FWIW
— Matt Gaetz (@mattgaetz) December 4, 2019
Rep. Matt Gaetz (R-Fla.), himself a lawyer, though not a constitutional scholar, also disagrees with 'Prophetess' Grace. Answering criticism of his call to impeach Obama in December 2019, he assured Jake Sherman, "You actually can impeach a former president, FWIW".
Not that anyone need take fruitloop, Amanda Grace's opinion on the niceties of US constitutional law, seriously, but there is actually some unsettled debate on the matter of impeaching former officials, unsettled partly because it's never really been tested at this level before. The argument is over the interpretation and the intent of two Articles:
- Article II, Section 4 of the Constitution, says, “The President, Vice President and all civil officers of the United States, shall be removed from office on impeachment for, and conviction of, treason, bribery, or other high crimes and misdemeanors.”
- Article I, Section 3, says, “Judgment in cases of impeachment shall not extend further than to removal from office, and disqualification to hold and enjoy any office of honor, trust or profit under the United States.”
So, those convicted face two penalties - removal from office, and disbarment from holding future office, the latter being the only relevant penalty for a former official, meaning the purpose of impeachment is not solely to sack a corrupt official, but also to prevent them from ever holding office again.
The other argument is over the intent of the people who framed these articles, and it surely can't have been their intention to build in a massive loophole that would render the entire thing moot and unusable - namely, by offering the escape route of resignation to avoid the penalty of being disbarred in the future, and the ignominy of being convicted.
Be that as it may, the reality is that Congress has the right to bring articles of impeachment against a former office holder, and has decided to do so, as is their constitutional right; and the Senate now has a constitutional duty to hold a formal trial once articles of impeachment have been brought before them, to which they are bound by their oath of office. The argument over whether the Senate can then convict under the Constitution is a separate one altogether.
The moral of this story is, if you want to understand the US Constitution and the powers of the legislature, ask a constitutional lawyer, not a deluded fruitloop who hears voices and even understands what they mean when they don't say anything - especially when what they don't say is what she doesn't want them to say anyway.
What is the probability that she is just plain lying because she is too embarrassed about making false prophesies to admit she made them up too and got it wrong?

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The Fundamentalist Christian Child Pornographer and Trump Aide.
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Christmas at the White House with Trump's Ad designer, child pornographer and paedophile rapist, Ruben A. Verastigui. |
Of course it would be wrong to suggest that all Trump's supporters and staffers share his lack of moral scruples in sexual matters, but this one certainly did.
In fact, when he was working for the Senate Republican Conference and Christian pro-life groups, and designing social media ads for Donald Trump's Make America Great Again Committee and Donald J Trump for President, Inc., Ruben A. Verastigui was also trading in child pornography and telling his online pal and fellow paedophile:
Well like I said babies are some of my biggest turn-ons and beast. Young rape… Fuck I love all that.According to this report in The Daily Beast:
D.C. Metropolitan Police arrested Ruben A. Verastigui on Friday after an investigation revealed he allegedly “distributed, received, and possessed images of child pornography” between March 2020 and February 2021. Jared Holt, resident fellow at the Atlantic Council’s Digital Forensic Research Lab, first reported Verastigui’s arrest on Twitter.
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Wednesday, 10 February 2021
Trump's Legacy - How Trump Made America Hate Again
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Police clash with a mob of Trump supporters who breached security and stormed the U.S. Capitol building on Jan. 6, 2021. Photo: Mostafa Bassim/Anadolu Agency via Getty Images |
What happens when an advanced nation elects an incompetent oaf with a narcissistic personality disorder and the emotional maturity and self-control of an over-privileged adolescent, gives him a Twitter account and his own room and tells him he runs the world?
We spent the last 4 years finding out when America did just that in 2016. As this article by Michael Dimock and John Gramlich of the Pew Research Center, based largely on Pew Research polling over the period, shows, it left American society and the Republican Party deeply divided and at one point on the brink of violent insurrection, and America massively diminished in the eyes of the world.
Trump became the first world leader to try to govern (with his idea of government) through a Twitter account. Policies were announced and people were sacked not after discussions with colleagues and attempts to reach consensus but on a whim, often in the small hours of the morning by a Twitter tweet in response to an item on one of the right-wing disinformation TV networks, such as Fox News.
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Tuesday, 9 February 2021
Evolution News - Our Common Ancestry in Fish
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Polypterus bichir |
Humans, like all terrestrial tetrapods, have a couple of major differences with the bony fish we are all believed to be descended from via an intermediate species such as Tiktaalik roseae, which crawled out onto land about 370 million years ago; the major differences being our jointed limbs and our lungs, all thought to be adaptations to walking on land and breathing air.
However, researchers at the University of Copenhagen believe they have found evidence to show that these structures could have been present in our ancestral fish some 50 million years before that. In fact, lungs may be the forerunner of the swim-bladder found in bony fish, rather than the swim-bladder being the forerunner of lungs.
The conventional view is that bottom-feeding fish, in low-oxygen environments, used their swim-bladder as a fresh-air supply by gulping air from the surface. The swim-bladder is connected to the gut. This, over time, evolved into the lungs and enabled this bottom-feeders to use the limbs they were evolving to crawl around in the silt, to come out onto land.
This research challenges that view by suggesting that some early bony fish may have had lungs that later evolved into swim-bladders in fish that needed to vary their buoyancy while some retained them as functional lungs which server the purpose of a fresh air store for foraging in an anoxic environment.
Monday, 8 February 2021
Evolution News - Evolution of Skin, Fur and Feather Colours

Summary of Current Understanding of the Location of Melanosomes in Different Body Tissues and Organs and Putative Functions in Major Vertebrate Classes.
Functions of Melanin in Ancient Vertebrates
A team of palaeontologists from University College Cork (Coláiste na hOllscoile Corcaigh), Ireland have uncovered how melanin, the pigment that now gives mammals and birds the colours in their skin, fur and feathers, once had a different function in our evolutionary ancestors, but, because of one of those effects of the utilitarian 'design' process of evolution by natural selection, it was also toxic. Unless, as a creationist who believes in intelligent [sic] design, you believe toxicity was a problem deliberately created so it could be solved with a clunky work-around later.
Of course, the work debunks intelligent [sic] design creationism simply by revealing the facts, especially its latest ploy - evolution = devolution!
Melanin initially evolved as part of a mineral storage system which also played a role in immunity, and was stored in several internal organs in the bodies of early amphibians and reptiles. But it has a tendency to produce free radicles and is thus mildly toxic. The benefits of a functional, albeit primitive, immune systems outweighed the damage done, but as later animals evolved improved immune systems - given added impetus by the toxic melanin, the dynamic shifted so that the net result of melanin in the internal organs was detrimental, producing selection pressure to remove it to a place of safety - namely, outside the body in the outer layer of the skin, in hair and feathers of the evolving mammals and birds.
This in turn created selection pressure favouring colouration for camouflage, display, etc, as well as protection from harmful solar radiation, so we now have a rich diversity in hair and feather patterns in the mammals and birds.
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Sunday, 7 February 2021
Religion Declining Even in Former Devout Islamic and Catholic Countries

The increasing rejection of religion which we have seen in most of the predominantly former Christian Western industrialised world since the mid 20th century, is now also being seen in the predominantly Moslem parts of the Middle East according to a poll conducted by the Arab Barometer, a research group based in Princeton University and the University of Michigan. The poll was the subject of a recent article in The Economist.
Coincident with, or maybe because of, this loss of faith, there is a corresponding fall in the trust of political parties and religious leaders who, in some countries are one and the same.
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