July 2023
Mitochondria communicate intensively with their host, the higher (eukaryotic) cell.

Two mitochondria from mammalian lung tissue displaying their matrix and membranes as shown by electron microscopy
Four Scientists from Goethe University, Frankfurt, Germany have shown just how fully mitochondria have integrated into their endosymbiotic host cells over the course of their evolutionary history.
First a little background from ChatGPT3:
Mitochondria and how they evolved>
Mitochondria are double-membraned organelles found in the cells of most eukaryotic organisms, including plants, animals, fungi, and protists. They play a crucial role in cellular respiration, where they generate adenosine triphosphate (ATP), the primary energy currency of cells. Mitochondria are believed to have evolved from endosymbiosis, a process where one organism lives within another and both organisms benefit from the relationship.
The endosymbiotic theory suggests that mitochondria originated from a free-living bacterium that was engulfed by an ancient eukaryotic cell. Over time, the bacterium and the host cell developed a symbiotic relationship, where the bacterium provided energy through respiration, and the host cell provided protection and nutrients. Eventually, the bacterium lost some of its independence and became a specialized organelle within the host cell – the mitochondrion.