Malevolent Designer - Creationism's Putative Desiger Designed A Way to Prevent Cancer Spreading - And Gave It To Sea Cucumbers!

A sugar compound found in sea cucumbers could hold the key to stopping the spread of cancer, according to a recent UM-led study published in Glycobiology.

Graphic by Stefanie Goodwiller
University Marketing and Communications

Sea Cucumbers Could Hold Key to Stopping Cancer Spread | Ole Miss

Imagine you're a designer, and you've created a species — humans — for whom you have a particular fondness. Only, something keeps going dreadfully wrong with your blueprint. A large number of them keep dying because their cells become cancerous when they fail to replicate properly, and these cancers then spread to other organs, which ultimately give up the ghost.

Now, you can’t quite work out why these cancers start. For some reason, you've included substances called glycans on the surfaces of cells, and — just to complicate things — you’ve made cancer cells produce an enzyme called Sulf-2, which alters these glycans to help the cancer spread. Your solution? A stroke of genius: create another enzyme that inhibits Sulf-2. And lo! It works.

So, who do you give this life-saving enzyme to?

If you're creationism’s supposedly super-intelligent designer, you don’t give it to your favourite species — the one made in your own image, no less. No, instead you bestow this miracle molecule upon… sea cucumbers. A species that, incidentally, doesn’t even have a problem with cancer.

This, if they actually understood the subject properly, is what Intelligent Design creationists consider compelling evidence of a supremely intelligent designer.

The discovery that sea cucumbers possess this enzyme was made by researchers at the University of Mississippi and Georgetown University in Washington, DC. Their findings are published in the journal Glycobiology and can be read here.

It’s also neatly summarised in a University of Mississippi news article:

Malevolent Design - The Sneaky Way TB Keeps On Making Us Sick

Credit: Md Ariful Islam

Study discovers DNA switch that controls TB growth – and could help unlock its antibiotic resistance secrets | University of Surrey

If you're an omniscient, omnipotent, malevolent designer of parasites — such as the bacterium that causes tuberculosis in humans — then you're hardly going to let a little thing like the immune system (which you supposedly also designed to protect them) or even the development of medical science and antibiotics spoil your fun in causing random suffering, are you? Naturally, you'd equip your creation with mechanisms to overcome these obstacles.

Within the framework of Intelligent Design creationism, that's precisely what this recent discovery should look like — at least to those creationists who don't simply ignore the obvious and pretend it isn't there. Scientists from the Universities of Surrey and Oxford have discovered that Mycobacterium tuberculosis uses a reversible process known as ADP-ribosylation to modify its DNA, controlling both replication and gene expression. This allows the bacterium to remain dormant for extended periods and reactivate when environmental threats, such as immune responses or antibiotics, have passed.

This presents a problem for creationists who insist on believing in a benevolent creator deity and simultaneously hold that features such as irreducible complexity and complex specified information are sure signs of intelligent design—claims promoted by Discovery Institute fellows Michael J. Behe and William A. Dembski. Since Mycobacterium tuberculosis displays these very characteristics, so either it was designed specifically to cause suffering, or those characteristics are not the reliable indicators of divine design that Behe and Dembski claim, and their entire argument collapses.

This discovery was recently published open access in The EMBO Journal, and further details are available in the University of Surrey press release:

Creationism Refuted - Exquisite Fossils From 226 Million Years Before 'Creation Week'

The Karoo Basin is a rich source of fossils for the Permian Period of life.

Image © WOLF AVNI/Shutterstock

Other life of this time included the lizard-like ancestors of tortoises, large amphibians that lurked like crocodiles just below the water surface, and forests dominated by a tree called Glossopteris with an understorey of spore-producing plants such as mosses, ferns and horsetails.

Photo: PEXELS

Exquisite new fossils from South Africa offer a glimpse into a thriving ecosystem 266 million years ago

In the realm of palaeontology, few discoveries are as illuminating as those that offer a window into ecosystems long vanished. A recent study published in The Conversation by palaeontologist Rosemary Prevec of Rhodes University, South Africa, unveils such a discovery: an exquisitely preserved fossil site in South Africa's Northern Cape province, dating back 266 million years to the middle Permian period. This site reveals a thriving ecosystem teeming with diverse plant life and a myriad of insect species, providing an unprecedented glimpse into pre-dinosaur terrestrial life.[1]

The significance of this find extends beyond its immediate scientific value; it directly challenges fundamental creationist assertions. By presenting concrete evidence of complex ecosystems existing millions of years before the advent of humans, it undermines the young-Earth creationist timeline that posits a 6,000 to 10,000-year-old Earth. The detailed stratigraphy and radiometric dating techniques employed corroborate the Earth's ancient history, aligning with the broader scientific consensus on geological and biological evolution.

Moreover, the discovery underscores the continuity and gradual progression of life forms, countering the notion of sudden creation. The intricate details preserved in these fossils—ranging from delicate insect wings to diverse plant structures—highlight the complexity and diversity of life well before the emergence of humans. Such findings reinforce the evolutionary narrative of life's development over hundreds of millions of years, offering tangible evidence against creationist models that reject evolutionary theory.

Rosemary Prevec's article in The Conversation is reprinted here under a Creative Commons licence, reformatted for stylistic consistency:

Creationism Refuted - Evolution By Advantageous Mutation

This gene variant contributed to the dietary and physiological evolution of modern humans | ScienceDaily

One of the enduring claims in creationist circles is that mutations are invariably harmful—deleterious at best, fatal at worst—and thus incapable of driving evolutionary progress. This notion underpins Michael J. Behe's concept of "devolution," which posits that genetic changes represent a decline from an assumed state of original perfection. Yet, this perspective fails to account for how such "inferior" mutations could supplant their "perfect" predecessors in a population. Moreover, if a genome were truly perfect, it would replicate without error, precluding any mutations—and, by extension, any evolutionary change.

A recent study published in Cell Genomics challenges this dogma by identifying a regulatory variant of the ACSF3 gene that appears to have played a significant role in human evolution . This variant, known as rs34590044-A, enhances the expression of ACSF3 in the liver, influencing both stature and basal metabolic rate (BMR). Notably, the effects of this mutation are amplified in individuals consuming meat-rich diets, suggesting a link between genetic adaptation and dietary shifts in human history.[1.1,2.1]

The ACSF3 gene encodes an enzyme involved in mitochondrial fatty acid synthesis, a critical process for energy metabolism. Increased expression of ACSF3 has been associated with improved mitochondrial function and bone formation, potentially contributing to greater height and higher BMR in modern humans. These findings underscore the role of beneficial mutations in human adaptation and evolution, directly contradicting the creationist assertion that mutations cannot produce advantageous traits.[3.1,4.1]

This discovery not only provides insight into the genetic factors influencing human physiology but also exemplifies how mutations can facilitate evolutionary advancements, thereby challenging the notion that all genetic changes are inherently detrimental.

The team from Human Phenome Institute, Zhongshan Hospital and School of Life Sciences, Fudan University, Shanghai, China with Mark Stoneking, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, have recently published their findings in the open access Cell Press journal, Cell Genomics.

Unintelligent Design - Bizarre Heath-Robinson Reproduction In A Marine Worm

[Body]

Close-up of female stolen – one of the independent reproductive units – from the worm Ramisyllis kingghidorahi. It has already sprouted eyes and is swimming free to find a stolon of the opposite sex with which to reproduce.

Information for the Media - Georg-August-Universität Göttingen

As a supposed product of intelligent design, the reproductive process of the branching marine worm Ramisyllis kingghidorahi is nothing short of bizarre—especially when one considers that many of its marine worm relatives manage perfectly well with far more straightforward, functional reproductive strategies, free from the Heath-Robinson complexity seen in R. kingghidorahi.

This remarkable worm comprises a branching network of segments, the ends of which can transform into free-living reproductive units known as stolons. These stolons firstly grow a pair of eyes then detach from the main body and swim off in search of a partner—another stolon of the opposite sex.

Yet the most pressing question for biologists isn’t why such a labyrinthine reproductive system evolved, but how it is controlled and coordinated across the worm’s sprawling body. This is precisely the mystery tackled by a team of researchers from Georg-August-Universität Göttingen, Germany.

Their research has just been published, open access, in the journal BMC Genomics.

Malevolent Or Incompetent Design? - Or Just Mindless Evolution?

Chikungunya virus has become a disease of global concern due to its potentially disabling consequences and its efficient transmission.

The Aedes mosquito is the primary vector for the Chikungunya virus

LJI scientists uncover clues to how a viral infection can lead to arthritis-like disease – lji.org

Scientists believe they have uncovered a mechanism by which a viral infection can trigger a persistent autoimmune response, leading to chronic and often severe pain.

If fully understood, this discovery poses a significant challenge to Intelligent Design (ID) creationism. Under the ID paradigm, such an outcome leaves us with two unpalatable options: either the designer is incompetent, having failed to foresee the consequences of a poorly calibrated immune system, or the suffering inflicted on random individuals is intentional—engineered by design.

This finding also reignites a long-standing issue for creationism: the existence of parasites, particularly viruses. According to criteria promoted by Discovery Institute fellows William A. Dembski ("complex specified information") and Michael J. Behe ("irreducible complexity"), viruses must be regarded as the product of intelligent design. Yet these same entities are responsible for making us ill—seemingly by the same designer who supposedly crafted our immune system to protect us from them. The contradiction is striking.

The explanation stems from recent work by a research team at the La Jolla Institute for Immunology and is published in Cell Reports Medicine.

Abiogenesis News - Closing Creationism's Favourite God-Shaped Gap - Still No God(s) Found

Diagram of an early cell membrane.

AI Generated image (ChatGPT4o)

How membranes may have brought about the chemistry of life on Earth | Department of Biology

Another hefty spadeful of science has just been shovelled into one of creationism’s favourite god-shaped gaps: the ever-shrinking mystery of abiogenesis. This is the gap that, through the intellectually dishonest tactic of the false dichotomy, creationists claim as evidence for their chosen deity.

Not only is this approach scientifically bankrupt, it also conveniently spares them the bother of providing any evidence or a testable mechanism of their own. For a target audience conditioned to see science as an attempt to disprove their god, the logic goes: if science is wrong—or even just incomplete—then “God did it!” wins by default.

But that dreaded moment for creationists, when science finally closes the gap and, like every other gap in history, finds no need for gods or magic in the explanation, draws ever nearer. The latest discovery bringing us closer comes in the form of new research into the origin and function of membranes—an essential step on the path from chemistry to life.

This particular piece of gap-filling comes from a paper published in PLOS Biology, authored by a team led by Professor Thomas Richards, Professor of Evolutionary Genomics in the Department of Biology at the University of Oxford. The researchers demonstrate that early cell membranes could not only have formed through natural processes, but also had the crucial ability to control what passed through them.

In doing so, they explain what had been something of a mystery and a favourite claim of ID creationists - the chirality of 'living' molecules where all amino acids have the same chirality. Creationists claim this shows the hand of an intelligent designer. This work shows it has a natural explanation.

Creationism Refuted - Now It's an Australian Tree Frog From 55 Million Years Before 'Creation Week'.

Artist’s reconstruction of the new species Litoria tylerantiqua (right) and previously described species Platyplectrum casca (left) from Murgon, south-eastern Queensland

Samantha Yabsley
https://www.instagram.com/s.h.y_art.

Clockwise from bottom: An artist’s reconstruction of a turtle Murgonemys braithwaitei, a bird Murgonornis archeri, a mammal Thylacotinga bartholomaii, a bat Australonycteris clarkae and a frog Platyplectrum casca from Murgon, south-eastern Queensland.

Peter Schouten

Australia’s oldest prehistoric tree frog hops 22 million years back in time

In addition to the recent discovery of early reptile tracks in Australia—dated to 350 million years before 'Creation Week'—creationists have just been given another reason to resent Australia: a 55-million-year-old fossil tree frog.

The discovery was made by three palaeontologists at the University of New South Wales in Sydney, NSW, Australia. Their findings have just been published, open access, in the Journal of Vertebrate Paleontology. It will no doubt take some of creationism's sharpest minds to devise excuses for dismissing this evidence, while continuing to cling to the childish fantasy that Earth was conjured into existence by a magical, immaterial deity just 6,000 to 10,000 years ago—along with all life, fully formed and without ancestors.

The first line of attack will likely involve misrepresenting the dating methods used, in an attempt to cast doubt on their reliability, followed by accusations that the scientists falsified their data to conform to evolutionary 'dogma' and secure publication.

What creationists must never do, however, is admit that the fossil really does date to 55 million years ago. To do so would be to concede that a literalist interpretation of the Genesis creation story is false—thereby undermining the entire premise that the Bible was written by, or inspired by, an all-knowing creator god.

Creationism Refuted - New Finding Shows That Reptiles Were Around At Least 350 million Years Before 'Creation Week'

Early amniote reconstruction.

Martin Ambrozik.

Fossil tracks revise march of early life on Earth – News

In a paper that creationists will no doubt feel compelled to ignore, misrepresent, or dismiss, scientists report the discovery of reptile tracks in 350-million-year-old Australian rocks. This remarkable find pushes back the earliest known trace of reptiles by some 40 million years.

For mainstream science, this discovery provides further clarification of the timeline for the evolution of terrestrial tetrapods. However, for creationists—who continue to compress Earth's 3.8-billion-year history into a mere 6,000 to 10,000 years in order to preserve a literal interpretation of Genesis—it presents yet another challenge to their beliefs.

It is the kind of evidence that science routinely uncovers, forcing creationists into ever more creative contortions to avoid confronting the reality of evolution.

The discovery was made by Professor John Long of Flinders University and colleagues, who have detailed their findings and their significance in a Flinders University press release. Additionally, Professor Long, together with Grzegorz Niedzwiedzki and Professor Per Ahlberg of Uppsala University, Sweden, has published an open-access article discussing the research in The Conversation.

Their article in The Conversation is reproduced here under a Creative Commons license, reformatted for stylistic consistency:

Malevolent Designer - How The Influenza Virus Appears To Be Intelligently Designed to Make Us Sick

Confocal microscopy of a cell (magenta, cell nucleus in blue) of the A549 cell line on immobilized influenza viruses (green).

© HZI / Broich

Influenza virus. 3D illustration showing surface glycoprotein spikes hemagglutinin purple and neuraminidase orange.

Image Credit: Kateryna Kon / Shutterstock.

HZI | How influenza viruses communicate with cells

In their attempts to pass creationism off as legitimate science, Discovery Institute fellows William A. Dembski and Michael J. Behe have unwittingly undermined their own case. Their arguments—largely based on a classic god-of-the-gaps fallacy and a false dichotomy—can just as easily be turned against the very idea that their supposed intelligent designer is the God of the Christian Bible.

While they stop short of making that claim explicitly, the infamous Wedge Document [1.1], which outlines the political aims and strategy of the Discovery Institute, leaves no doubt: their ultimate goal is a fundamentalist Christian theocracy governed by so-called "Christian principles" and that selling the idea that 'Intelligent Design' creationism is real science, is a fundamental aspect of that strategy because it would enable them to teach creationism to children at taxpayers' expense, under the guise of real science.

And yet, even within their own paradigm, the evidence points not to a benevolent deity but to something far more disturbing.

Take, for example, recent research from the Helmholtz Centre for Infection Research, which offers a striking illustration of what Dembski might call "complex specified information" and what Behe might regard as "irreducible complexity". The study reveals how the influenza virus is 'designed'—if one accepts their terminology—with remarkable sophistication to circumvent our defences and invade human cells. Ironically, these very defences are what the same creationists insist were intelligently designed to protect us—against, among other things, intelligently designed viruses. We are left, according to this worldview, with the absurd spectacle of a designer who engineers both the pathogens and the immune system meant to defend us from them—a system that, demonstrably, does not always work.

And this is held up as evidence of a supreme intelligence!

Far from supporting creationist claims, these findings align far more convincingly with what we would expect from a blind, indifferent process of evolution—one that requires no designer at all. Once again, creationists are faced with an uncomfortable dilemma: either accept the notion of a malevolent and inept designer or acknowledge the explanatory power of natural selection and evolutionary biology.

Refuting Creationism - More Pterrible News For Creationists As Scientists Track The Evolution of Terrestrial Pterosaurs

Quetzalcoatlus northropi (artist's impression)

Witton MP, Naish D (2008),
CC BY 3.0, Link

Ptero Firma: footprints pinpoint when ancient flying reptiles conquered the ground | News | University of Leicester

False-colour depth map revealing the shape and pressure of each step, showing that these creatures bore more weight on their hands while walking.

Most people—apart, perhaps, from creationists who deny such creatures ever existed—are aware that a group of reptiles evolved the ability to fly and took to the skies long before birds and bats emerged to exploit this medium.

What many people don’t know, however, is that some members of this group, including larger species, later returned to land and adopted a coastal wading lifestyle. We know this because their fossilised tracks have been found preserved in what was once coastal mud.

Young Earth creationists routinely point to geological formations derived from coastal or estuarine mud as 'evidence' of a supposed global flood, yet they consistently fail to explain how such a flood could have preserved so many footprints—left by waders such as ducks, geese, redshanks, and sandpipers—as well as delicate raindrop impressions. Even harder to explain is the evidence showing that these footprints were made at different times, spanning several million years, up until the mass extinction caused by an asteroid impact 66 million years ago.

And disconcertingly for creationists, a team of palaeontologists led by Robert Smyth, a doctoral researcher in the Centre for Palaeobiology and Biosphere Evolution (School of Geography, Geology and the Environment) at the University of Leicester, has demonstrated that these fossil footprints can be used to trace the evolutionary history of the pterosaurs that made them.

Refuting Creationism - Homing In On Consciousness - No Gods Involved

Landmark experiment sheds new light on the origins of consciousness - Allen Institute

Consciousness, like the Big Bang and abiogenesis, represents a gap in scientific understanding that creationists eagerly exploit as a place to insert their evidence-free deity — the classic “God of the gaps” fallacy. This false dichotomy is the lifeblood of creationism, which appeals to the scientifically illiterate and culturally chauvinistic creationists who view science as a rival to their preferred local religion. According to this view, if science cannot yet explain something, or if it has ever been wrong, then “God did it” wins by default.

However, a major new study suggests that science is closing in on a natural explanation for consciousness. The findings support the idea that consciousness is an emergent property of neurophysiology, leaving no room — or need — for supernatural explanations. In a landmark 2019 collaborative experiment involving human subjects, researchers from the Allen Institute tested two competing theories of consciousness against one another. They published their findings today in Nature, claiming the study marks a pivotal moment in the quest to understand this elusive phenomenon. Further details are available in an Allen Institute news article.

Creationism Refuted - Science Has Found Evidence of Life On A Planet Outside the Solar System

Artist's impression of the exoplanet K2-18b.

Credit: A. Smith/N. Mandhusudhan

Artists light-hearted impression of life on K2-18b.

AI-generated image

Strongest hints yet of biological activity outside the solar system

The day long anticipated by those who understand both science and theology may finally have arrived. Scientists have detected—with a 99.7% probability—the unmistakable signs of life on the distant exoplanet K2-18b.

Although this degree of certainty doesn't yet satisfy the rigorous standards of science, which typically require a confidence level of greater than 99.99994%, researchers anticipate surpassing that threshold within the next 16 to 24 hours (as of this article's publication).

The theological implications of this discovery are profound. If confirmed, as now seems highly likely, it would indicate that Earth is not unique as a cradle of life, directly challenging biblical narratives which position Earth exclusively as the divinely chosen habitat for humanity. The Bible remains thoroughly anthropocentric and geocentric, offering no indication that life or divine creation occurred elsewhere in the comparatively small and flat universe it describes.

For creationists, this finding significantly undermines their long-standing argument—summarised by the simplistic slogan, "You can't get life from non-life"—which claims life could only arise through divine intervention. The presence of life on K2-18b demonstrates that life can indeed emerge naturally under the right conditions, suggesting such events may be far more common across the universe than creationist arguments would allow. Indeed, with potentially trillions of planets sharing Earth-like conditions, life may not only be possible but prevalent.

This discovery also challenges creationist claims about Earth's position in the so-called 'Goldilocks zone'. Creationists frequently argue that Earth's precise placement around the Sun proves divine intent. However, the existence of life-supporting conditions on K2-18b shows that such habitable zones are not rare, singular phenomena but commonplace, existing around countless other stars across the cosmos.

The discovery, by astronomers, led by the University of Cambridge, using data from the James Webb Space Telescope (JWST), is the subject of an open access paper in The Astrophysical Journal Letters and is described in a Cambridge University press release by Sarah Collins:

Refuting Creationism - Filling The Gaps and Shrinking That Ever-Shrinking Little God

Helmetia expansa

Holotype of Helmetia expansa USNM 83952, dorsal view.

Jean-Bernard Caron and Sarah Losso.

Ancient fossil sheds big light on evolution mystery: solving a 100-year arthropod mystery | Department of Organismic and Evolutionary Biology

Creationist apologetics often involve attributing phenomena that science cannot yet explain to divine intervention, relying on the assumption that gaps in scientific knowledge serve as evidence for the existence of a deity. This approach frequently employs the false dichotomy fallacy, suggesting that if science lacks an explanation, then "God did it" by default. Such reasoning does not establish the existence of a god capable of addressing these gaps; instead, it often depends on the cultural biases of the audience to support this conclusion.

However, science continually seeks to fill these gaps with evidence-based explanations. A recent example is the formal description of the Cambrian fossil Helmetia expansa, which provides insights into arthropod evolution during the Cambrian Period. This period is often mischaracterized by creationist narratives as a time when multiple distinct body plans appeared suddenly without ancestral forms, purportedly indicating a single act of creation.

The study, published in the *Journal of Systematic Palaeontology* by Professor Sarah R. Losso and Javier Ortega-Hernández of Harvard University's Museum of Comparative Zoology and Department of Organismic and Evolutionary Biology, along with Jean-Bernard Caron of the Royal Ontario Museum's Department of Natural History (Palaeobiology Section) in Toronto, Canada, offers a comprehensive analysis of Helmetia expansa. Their research reveals that Helmetia expansa is an arthropod related to trilobites, shedding light on the evolutionary diversification of this group during the Cambrian. This finding provides evidence of gradual evolutionary processes, countering claims of abrupt appearance without ancestral lineage.

The study is further explained in a press release from Harvard University, which details how this research resolves a 100-year-old mystery surrounding this Cambrian arthropod.

Refuting Creationism - A New Denisovan Jaw Bone - From The Coast of Taiwan

A fishing vessel dredged this fossil jawbone, now confirmed as Denisovan, from the Taiwan Strait.

Yousuke Kaifu

AI-generated impression of a Denisovan male.

ChatGPT4o

Fossil jawbone reveals mysterious Denisovans lived in ancient Taiwan | Science | AAAS

The Denisovans—an enigmatic group of archaic humans known mostly through ancient DNA—just became a little less mysterious. In a groundbreaking discovery announced this month, researchers have confirmed that a robust fossilised jawbone recovered from the seabed near Taiwan belongs to a Denisovan.

While no recoverable DNA remained, scientists used protein analysis—specifically paleoproteomics—to identify the jaw as Denisovan, marking the most southerly and eastern confirmed presence of these ancient humans to date.

This discovery not only expands the known geographic range of Denisovans dramatically but also sheds light on their adaptability, dietary ecology, and evolutionary identity. It may even help pave the way for giving them an official scientific name.

Refuting Creationism - How Large Herds Of Rhino Roamed North America - 12 Million Years Before 'Creation Week'.

UC researchers discovered that prehistoric rhinos like these that shared a waterhole 12 million years ago lived in enormous herds.

Photo/John Haxby/The University of Nebraska State Museum

Ash from the eruption of a volcano in Yellowstone preserved more than 100 specimens of a prehistoric rhino at Nebraska's Ashfall Fossil Beds State Historical Park.

Photo/John Haxby/The University of Nebraska State Museum

UC study finds evidence that prehistoric rhinos lived in huge herds | University of Cincinnati

Recent research has presented yet another problem for young-Earth creationism, which asserts that the Earth is only a few thousand years old, and that all existing species were created simultaneously without ancestors.

A study conducted by paleontologists from the University of Cincinnati provides compelling evidence that large herds of the extinct rhinoceros species, Teleoceras major, inhabited North America approximately 12 million years before creationism's mythical 'Creation Week'.

This conclusion is derived from isotopic analyses performed on fossils of these rhinos, which were preserved in volcanic ash at the Ashfall Fossil Beds in Nebraska. The fossils represent individuals that perished together at a waterhole, suggesting herd behavior. The study, titled "Enamel carbon, oxygen, and strontium isotopes reveal limited mobility in an extinct rhinoceros at Ashfall Fossil Beds, Nebraska, USA," was published in the journal Scientific Reports on April 4, 2025.

The University of Cincinnati further elaborated on these findings in a news release by Michael Miller, highlighting the evidence that prehistoric rhinos lived in substantial herds.

Unintelligent Design - Another Failure By Creationism's Blundering Designer

Machine for repairing broken mtDNA.

AI-Generated image
(with apologies to William Heath Robinson)

The graphic shows images of a cell under mtDNA replication stress made using so-called Correlative Light and Electron Microscopy (for short: CLEM). The mitochondrial DNA (mtDNA, green) is ejected from the mitochondria (magenta) and taken up by a lysosome, which contains the retromer (cyan). The highlighted section was also analysed using 3D-CLEM to obtain volumetric information.

Fig.: HHU/David Pla-Martín.

Medicine: Publication in Science Advances

Yet Another Workaround for a Flawed Design.

Researchers led by Professor Dr David Pla-Martín of Heinrich Heine University Düsseldorf, alongside colleagues from the University of Cologne, have uncovered yet another complex but error-prone workaround—this time, to fix a problem that stems from an earlier design flaw.

They have identified a mechanism used to repair mitochondrial DNA (mtDNA) when it breaks. From an intelligent design perspective, mitochondria — once free-living bacteria—were supposedly the 'quick fix' to give eukaryotic cells the ability to efficiently convert glucose into adenosine triphosphate (ATP) using oxygen. ATP is the primary energy currency used in metabolic reactions, formed from adenosine diphosphate (ADP) and phosphate.

A truly intelligent designer, however, could have simply endowed cells with this biochemical machinery from the start—no need to incorporate foreign bacteria complete with their own DNA. But apparently, that would have been too simple.

This convoluted solution, predictably, comes with problems. Mitochondria often replicate their DNA imperfectly, or the DNA becomes damaged, leading to mitochondrial failure and a range of diseases. So, yet another layer of biological complexity has evolved to patch up the broken mtDNA. And, in classic Heath Robinson fashion, this repair mechanism is itself error-prone.

Refuting Creationism - The Long Pre-'Creation Week' Evolutionary History of Bacteria

The Great Oxidation Event

AI-Generated Image (ChatGPT4o)

Machine learning helps construct an evolutionary timeline of bacteria - UQ News - The University of Queensland, Australia

A helpful analogy employed by Richard Dawkins in Unweaving the Rainbow illustrates the vastness of evolutionary time:

Fling your arms wide in an expansive gesture to span all of evolution from its origins at your left fingertip to today at your right fingertip. All the way across your midline to well past your right shoulder, life consisted of nothing but bacteria. Multi-celled invertebrate life flowers somewhere around your right elbow. The dinosaurs originate in the middle of your right palm and go extinct around your last finger joint. The whole story of Homo sapiens and our predecessor Homo erectus is contained in the thickness of one nail-clipping.

We can construct such a timeline because, although microbial life leaves few conventional fossils, it does leave behind chemical signatures in ancient rocks—clues to how bacteria lived, metabolised, and evolved.

By correlating this geochemical record with genomic data, a multinational collaboration – led by researchers from the Okinawa Institute of Science and Technology, Japan, the University of Bristol, UK, Queensland University of Technology, Australia and the University of Queensland, Australia, has used machine learning to reconstructed an evolutionary tree of bacterial lineages. This allows us to trace how different taxa adapted to major environmental changes, such as the Great Oxidation Event (GOE). Remarkably, this study suggest that some microbes had already evolved the capacity to utilise oxygen even before it became abundant during the GOE.

The disturbing fact for creationists is not the evidence of common origins and descent with modification that this study reveals, but the fact that it all happened billions of years before their mythical 'Creation Week' when their god allegedly created a small flat planet with a dome over it in the Middle East. But then this is hardly surprising, since 99.9975% of the history of life on Earth happened before that alleged act of magic.

How the team of scientists conducted this study, and their conclusions are the subject of a research paper in Science and a news item from the University of Queensland, Australia:

Refuting Creationsm - Evolution By Loss of Genes, Horizontal Gene Transfer And Gene Duplication

Nitzschia sp

By Kristian Peters - Own work,
CC BY-SA 3.0,
Wikimedia

This article is best read on a laptop, desktop, or tablet

Nitzschia sing1 lives on the alginate in the cell walls of decaying brown algae.

A borrowed bacterial gene allowed some marine diatoms to live on a seaweed diet | PRESS-NEWS.org

A fundamental axiom of creationism is the claim that any loss of genetic information is invariably detrimental—so much so that any mutation resulting in such a loss would be fatal and could therefore play no role in evolution. A second axiom asserts that new genetic information cannot arise naturally and must instead be supplied by a supernatural intelligent designer.

Both of these assertions are demonstrably false. Nevertheless, they continue to feature in creationist apologetics, relying on the audience's ignorance and incredulity to pass as justification for belief in an intelligent creator.

To add further difficulty for creationist claims, scientists have now identified a marine diatom, Nitzschia sing1, that has not only lost the genes and organelles required for photosynthesis — present in its photosynthetic relatives — but has also adapted successfully without them. It achieved this by acquiring new genetic information through horizontal gene transfer from a marine bacterium. The transferred gene subsequently underwent extensive duplication and diversification into three gene families, each with complementary functions. Together, these 91 versions of the acquired gene enable N. sing1 to metabolise alginate, a carbohydrate found in the cell walls of brown algae such as kelp.

Refuting Creationism - People Of the Green Sahara - No Flood Noticed

View of the Takarkori rock shelter in Southern Libya.

© Archaeological Mission in the Sahara,
Sapienza University of Rome

View from the Takarkori rock shelter in Southern Libya.

© Archaeological Mission in the Sahara,
Sapienza University of Rome.

First ancient genomes from the Green Sahara deciphered

According to literal interpretations of biblical creationism, the first two humans were created approximately 6,000 years ago without any ancestors. Subsequently, around 4,000 years ago, the Earth was supposedly submerged by a global flood. According to this narrative, all present-day humans descended from the eight survivors who endured a year-long voyage in a large vessel accompanied by two (or, in some accounts, seven) individuals of each animal species. After the flood receded, these survivors are said to have repopulated a barren and sterile world in which all previously existing life had been destroyed.

In contrast, scientific evidence indicates that more than 7,000 years ago, human populations inhabited a Sahara region that was markedly different from today's desert. At the time, a wetter climate supported forests, grasslands, lakes, and rivers. These Saharan people were only distantly related to other non-African populations, as they had diverged from East and South African Homo sapiens around the same period—approximately 50,000 years ago—that modern non-African populations migrated out of Africa into Eurasia. Subsequently, the Saharan population remained largely isolated from both sub-Saharan African and Eurasian populations.

The critical distinction between these two accounts lies in their evidence base. Creationism relies solely on written narratives from a text of uncertain historical authenticity, whereas science relies upon verifiable, physical evidence, in this case DNA extracted from two mummified Saharan individuals discovered in Algeria.

This fundamental difference exemplifies the contrast between religion and science: religion typically relies on tradition, superstition, and narratives lacking empirical support, whereas science is grounded in observable evidence and logical deduction.

The evidence for the existence and origin of this Saharan population comes from the work of researchers at the Dept. of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. It's significance is that it argues against the green Sahara being one of the migration routes for modern humans out of Africa and a return migration back into Africa because the Saharan population were genetically distinct and have a very low level of Neanderthal DNA unlike the western Eurasian Homo sapiens.

The findings of the group are published open access in Nature. The research is described in a Max Planck Institute News release: