Unintelligent Design - Another Failure By Creationism's Blundering Designer

Machine for repairing broken mtDNA.

AI-Generated image
(with apologies to William Heath Robinson)

The graphic shows images of a cell under mtDNA replication stress made using so-called Correlative Light and Electron Microscopy (for short: CLEM). The mitochondrial DNA (mtDNA, green) is ejected from the mitochondria (magenta) and taken up by a lysosome, which contains the retromer (cyan). The highlighted section was also analysed using 3D-CLEM to obtain volumetric information.

Fig.: HHU/David Pla-Martín.

Medicine: Publication in Science Advances

Yet Another Workaround for a Flawed Design.

Researchers led by Professor Dr David Pla-Martín of Heinrich Heine University Düsseldorf, alongside colleagues from the University of Cologne, have uncovered yet another complex but error-prone workaround—this time, to fix a problem that stems from an earlier design flaw.

They have identified a mechanism used to repair mitochondrial DNA (mtDNA) when it breaks. From an intelligent design perspective, mitochondria — once free-living bacteria—were supposedly the 'quick fix' to give eukaryotic cells the ability to efficiently convert glucose into adenosine triphosphate (ATP) using oxygen. ATP is the primary energy currency used in metabolic reactions, formed from adenosine diphosphate (ADP) and phosphate.

A truly intelligent designer, however, could have simply endowed cells with this biochemical machinery from the start—no need to incorporate foreign bacteria complete with their own DNA. But apparently, that would have been too simple.

This convoluted solution, predictably, comes with problems. Mitochondria often replicate their DNA imperfectly, or the DNA becomes damaged, leading to mitochondrial failure and a range of diseases. So, yet another layer of biological complexity has evolved to patch up the broken mtDNA. And, in classic Heath Robinson fashion, this repair mechanism is itself error-prone.

Refuting Creationism - The Long Pre-'Creation Week' Evolutionary History of Bacteria

The Great Oxidation Event

AI-Generated Image (ChatGPT4o)

Machine learning helps construct an evolutionary timeline of bacteria - UQ News - The University of Queensland, Australia

A helpful analogy employed by Richard Dawkins in Unweaving the Rainbow illustrates the vastness of evolutionary time:

Fling your arms wide in an expansive gesture to span all of evolution from its origins at your left fingertip to today at your right fingertip. All the way across your midline to well past your right shoulder, life consisted of nothing but bacteria. Multi-celled invertebrate life flowers somewhere around your right elbow. The dinosaurs originate in the middle of your right palm and go extinct around your last finger joint. The whole story of Homo sapiens and our predecessor Homo erectus is contained in the thickness of one nail-clipping.

We can construct such a timeline because, although microbial life leaves few conventional fossils, it does leave behind chemical signatures in ancient rocks—clues to how bacteria lived, metabolised, and evolved.

By correlating this geochemical record with genomic data, a multinational collaboration – led by researchers from the Okinawa Institute of Science and Technology, Japan, the University of Bristol, UK, Queensland University of Technology, Australia and the University of Queensland, Australia, has used machine learning to reconstructed an evolutionary tree of bacterial lineages. This allows us to trace how different taxa adapted to major environmental changes, such as the Great Oxidation Event (GOE). Remarkably, this study suggest that some microbes had already evolved the capacity to utilise oxygen even before it became abundant during the GOE.

The disturbing fact for creationists is not the evidence of common origins and descent with modification that this study reveals, but the fact that it all happened billions of years before their mythical 'Creation Week' when their god allegedly created a small flat planet with a dome over it in the Middle East. But then this is hardly surprising, since 99.9975% of the history of life on Earth happened before that alleged act of magic.

How the team of scientists conducted this study, and their conclusions are the subject of a research paper in Science and a news item from the University of Queensland, Australia:

Refuting Creationsm - Evolution By Loss of Genes, Horizontal Gene Transfer And Gene Duplication

Nitzschia sp

By Kristian Peters - Own work,
CC BY-SA 3.0,
Wikimedia

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Nitzschia sing1 lives on the alginate in the cell walls of decaying brown algae.

A borrowed bacterial gene allowed some marine diatoms to live on a seaweed diet | PRESS-NEWS.org

A fundamental axiom of creationism is the claim that any loss of genetic information is invariably detrimental—so much so that any mutation resulting in such a loss would be fatal and could therefore play no role in evolution. A second axiom asserts that new genetic information cannot arise naturally and must instead be supplied by a supernatural intelligent designer.

Both of these assertions are demonstrably false. Nevertheless, they continue to feature in creationist apologetics, relying on the audience's ignorance and incredulity to pass as justification for belief in an intelligent creator.

To add further difficulty for creationist claims, scientists have now identified a marine diatom, Nitzschia sing1, that has not only lost the genes and organelles required for photosynthesis — present in its photosynthetic relatives — but has also adapted successfully without them. It achieved this by acquiring new genetic information through horizontal gene transfer from a marine bacterium. The transferred gene subsequently underwent extensive duplication and diversification into three gene families, each with complementary functions. Together, these 91 versions of the acquired gene enable N. sing1 to metabolise alginate, a carbohydrate found in the cell walls of brown algae such as kelp.

Refuting Creationism - People Of the Green Sahara - No Flood Noticed

View of the Takarkori rock shelter in Southern Libya.

© Archaeological Mission in the Sahara,
Sapienza University of Rome

View from the Takarkori rock shelter in Southern Libya.

© Archaeological Mission in the Sahara,
Sapienza University of Rome.

First ancient genomes from the Green Sahara deciphered

According to literal interpretations of biblical creationism, the first two humans were created approximately 6,000 years ago without any ancestors. Subsequently, around 4,000 years ago, the Earth was supposedly submerged by a global flood. According to this narrative, all present-day humans descended from the eight survivors who endured a year-long voyage in a large vessel accompanied by two (or, in some accounts, seven) individuals of each animal species. After the flood receded, these survivors are said to have repopulated a barren and sterile world in which all previously existing life had been destroyed.

In contrast, scientific evidence indicates that more than 7,000 years ago, human populations inhabited a Sahara region that was markedly different from today's desert. At the time, a wetter climate supported forests, grasslands, lakes, and rivers. These Saharan people were only distantly related to other non-African populations, as they had diverged from East and South African Homo sapiens around the same period—approximately 50,000 years ago—that modern non-African populations migrated out of Africa into Eurasia. Subsequently, the Saharan population remained largely isolated from both sub-Saharan African and Eurasian populations.

The critical distinction between these two accounts lies in their evidence base. Creationism relies solely on written narratives from a text of uncertain historical authenticity, whereas science relies upon verifiable, physical evidence, in this case DNA extracted from two mummified Saharan individuals discovered in Algeria.

This fundamental difference exemplifies the contrast between religion and science: religion typically relies on tradition, superstition, and narratives lacking empirical support, whereas science is grounded in observable evidence and logical deduction.

The evidence for the existence and origin of this Saharan population comes from the work of researchers at the Dept. of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. It's significance is that it argues against the green Sahara being one of the migration routes for modern humans out of Africa and a return migration back into Africa because the Saharan population were genetically distinct and have a very low level of Neanderthal DNA unlike the western Eurasian Homo sapiens.

The findings of the group are published open access in Nature. The research is described in a Max Planck Institute News release:

Refuting Creationism - Stone Tool Manufacture in China, 40-50,000 Before 'Creation Week'.

Quina technology was found in Europe decades ago but has never before been found in East Asia.

Ben Marwick

Discovery of Quina technology challenges view of ancient human development in East Asia | UW News

What may present a fascinating puzzle for science often deals a fatal blow to creationism — if only its adherents would acknowledge it. However, creationism remains a "brain-dead zombie", artificially kept alive by the manoeuvres of creationist leaders whose power and income rely upon it.

For instance, the recent discovery in China of stone tools exhibiting 'Quina technology', typically associated with Neanderthals, raises intriguing questions for archaeologists and anthropologists. Neanderthals were previously thought to have inhabited primarily western Eurasia, yet these Chinese artefacts, dated to between 50,000 and 60,000 years ago, suggest their influence or presence extended much farther east than previously known. These findings pose fascinating questions regarding ancient human migration and technological exchange.

However, these same discoveries directly contradict creationist beliefs that the Earth is merely 6,000 to 10,000 years old and that humans appeared through a special creation without ancestral links. While science thrives on unanswered questions and continuously adapts its theories based on new evidence, creationism relies rigidly on dogma. When its foundational claims are refuted, the entire belief system crumbles. Religion insists upon unreasonable certainty, whereas science flourishes through reasonable uncertainty.

The discovery of this evidence of Quina Technology was made at the Longtan archaeological site in southwest China by an international group of archaeologists, which included Professor Ben Marwick of Washington University, USA. It is first such discovery in Asia of a technology known to have existed in Middle Palaeolothic Europe and associated there with Neanderthals.

The question is, does this show that Neanderthals were more widespread than we thought, or has their technology been shared with other hominins such as the Denisovans? Or did the same technology arise independently in China?

Refuting Creationism - How A Couple of Chance Mutations Led to Big Brains in Humans

Microscopic image of a section of an electroporated, genetically modified chimpanzee brain organoid. Cell nuclei in blue, precursor cells in magenta, electroporated, genetically modified cells in green and dividing cells in orange.

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Homo habilis is an extinct hominid species that lived between 2.8 and 1.5 million years ago. It is considered to be one of the earliest members of the genus Homo, and its name means "handy man" in Latin, reflecting its ability to make and use tools.

How did the large brain evolve? | DPZ

Creationists often struggle to explain why closely related species share identical genes located at the same locus on the same chromosome, typically resorting to the argument of common design rather than common descent. Even more challenging for creationists is when these shared genes exhibit slight modifications that result in significant differences between species, strongly supporting descent with modification.

A compelling recent example involves two genes, NBPF14 and NOTCH2NLB, identified by researchers from the German Primate Center - Leibniz Institute for Primate Research (DPZ) and the Max Planck Institute of Molecular Cell Biology and Genetics. These genes, modified specifically in humans, appear to explain the larger and more complex human brain compared to chimpanzees and bonobos. The research shows that NBPF14 and NOTCH2NLB act synergistically: one gene increases the production of neural progenitor cells, while the other facilitates their transformation into neurons capable of forming more extensive neural connections.

Together, these genetic modifications account for the remarkable increase in the size and complexity of the human brain relative to our closest primate relatives.

For an explanation of how two mutations with a low probability can quickly spread through the gene pool when they act synergistically, see my book Twenty Reasons To Reject Creationism: Understanding Evolution, pages 17-20, in which, using the example of a bacterium and two beneficial mutations acting synergistically, I show that the time take for 50% of the population to have both mutations is actually shorter than the time for 50% of the population to have just one mutation because, the accelerating effect of synergy increases the probability of both being inherited together.

This can explain why a large-brained archaic hominin appeared relatively suddenly in the fossil record. As we shall see, the fact that at least one of our ancestral species went through a narrow genetic bottleneck was ultimately highly beneficial because this reduces the time taken for the whole gene pool to acquire a neutral mutation by genetic drift alone.

Refuting Creationism - How Earth Was Really Formed

Impression of molten Earth at 300 million years old

AI-Generated image (Chat GPT4.5)

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Artistic view of Earth’s interior during mantle solidification in the first hundreds of millions of years of Earth’s history. Gravitational segregation of dense, iron-rich magma (in orange) likely formed a basal magma ocean atop the core, that can explain the present-day structure of the lower mantle.

York U research sheds light on earliest days of Earth’s formation - News@York

According to creationist mythology, approximately 6,000 to 10,000 years ago, a supernatural entity conjured Earth into existence out of nothing. This planet, according to the myth, was initially a small, flat surface covered by a dome, centred around the vicinity of the Middle East.

In stark contrast to this mythological narrative, scientific evidence reveals a completely different history — one so profoundly distinct that any metaphorical interpretation of the myth quickly collapses under scrutiny. The Earth is neither flat nor limited to a small region around the ancient Canaanite hills; nor does it possess a dome overhead. No amount of linguistic gymnastics can transform that ancient depiction into anything remotely resembling Earth, although it may well have resembled the perception of Earth from the point of view of scientifically illiterate Bronze Age pastoralists who had never travelled more than a day or two's walk from their homeland and who though the sky was blue because of all the water above the transparent dome overhead.

As though any more refutation of the idea that the Bible contains an inerrant account of actual history, a recent study by a research team led by Assistant Professor Charles-Édouard Boukaré from the Department of Physics and Astronomy at York University in Toronto, Canada, sheds new light on Earth's early geological development. Their research demonstrates how Earth gradually cooled over its first 100 million years, providing valuable insights into the planet’s current thermochemical internal structure.

Refuting Creationism - Students Discover How The Mammalian Immune System Evolved.

Nebraska undergrads uncover ancient secrets of human immunity | Nebraska Today

(C–F) Expanded views of the interaction interface between STAT2 CCD and IRF9 IAD for mouse (C), human (D), Hypanus sabinus (E), and Stegostoma tigrinum (F). The interactions are observed in the crystal structure of the mouse STAT2-IRF9 complex (PDB ID: 5OEN) [19.1]. For humans and the two cartilaginous fishes, the interactions are based on the modeled structures of the STAT2-IRF9 complex. The key residues involved in the interface are labeled. The phenylalanine (F) on the STAT2 protein is colored in green. The four residues forming the cleft on the IRF9 protein are colored in magenta. The corresponding sequences of the interface area and other details are found in Supporting Information S1: Figure S3.

Recent research conducted by undergraduate students at the University of Nebraska–Lincoln has provided compelling insights into the evolutionary development of the human immune system. Under the guidance of Professor Luwen Zhang, students Vanessa Hubing, Avery Marquis, and Chanasei Ziemann co-authored two significant studies published in the Journal of Medical Virology. Their work elucidates the progression of immune regulatory mechanisms in vertebrates, highlighting the transition to more complex systems with the evolution of jaws. Additionally, they explored how a pseudogene, potentially introduced into primate DNA via a retrovirus approximately 60 million years ago, may have enhanced ancestral immune responses.

These findings offer robust evidence supporting the theory of evolution by demonstrating the gradual and adaptive changes in genetic material that have led to sophisticated immune functions in humans. The identification of a pseudogene's integration into primate DNA and its subsequent role in immunity exemplifies natural selection's influence on genetic composition over millions of years. Such evidence challenges creationist perspectives by providing concrete examples of evolutionary processes shaping complex biological systems, underscoring the dynamic nature of genetic evolution in response to environmental pressures.

During the course of evolution, these factors have evolved as additional layers of complexity to improve and refine a system which, as the product of an unplanned, utilitarian evolutionary process was a suboptimal compromise between the tendencies to over-react to some infections and fail to respond to others. An intelligently-designed sytem would need no such regulatory mechanisms. This is how we can tell that such overly-complex systems were not intelligently designed.

Malevolent Designer News - How C. difficile is Designed to Kill Off Competition in Our Gut

C. diff uses toxic compound to fuel growth advantage VUMC News

Like all organisms, and particularly pathogenic parasites that colonise our intestines, Clostridioides difficile (C. diff) must compete with other organisms for nutrients. This competition inevitably fuels evolutionary arms races.

For devotees of creationism’s ‘intelligent designer’, C. diff might appear to be a cunning response to medical science's successful use of antibiotics against bacterial pathogens. This is because C. diff is equipped with multiple antibiotic-resistance genes, allowing it to thrive in hospital environments. It often infects patients who are already vulnerable due to other health conditions or compromised immunity, making it a significant medical challenge.

Furthermore, if one follows William A. Dembski's reasoning, the ‘complex specified information’ in C. diff’s genome, which grants it a competitive edge, must logically be attributed to an intelligent designer. Michael J. Behe’s attempt to absolve his version of an intelligent designer by blaming ‘sin’, ‘genetic entropy’, or alleged ‘devolution’ fails here. A mutation that clearly provides an adaptive advantage cannot logically be termed a ‘devolution’ from a supposedly more ‘perfect’ ancestral state.

If creationism’s intelligent designer intended to kick people when they were down, it could hardly have done better than designing C. diff.

How C. diff competes for resource in our gut by waging chemical warfare against the other gut biota is the subject of a paper in the journal Cell Host & Microbe by researchers at Vanderbilt University Medical Center (VUMC). Their findings are described in VUMC News:

Refuting Creationism - Common Origins - Like Humans, Chimpanzees Use Engineering Skills to Make Tools

A Gombe chimpanzee using a termite fishing tool to fish termites.

Credit: Dr Alejandra Pascual-Garrido

A Gombe chimpanzee using a termite fishing tool to fish termites.

Credit: Dr Alejandra Pascual-Garrido

Research into chimpanzee ‘engineers’ has implications for understanding human technological evolution | University of Oxford

Not so long ago, it was commonly claimed that humans were exceptional due to their supposedly 'unique' ability to make and use tools. This assertion was often used to reinforce the idea that humans occupied a special position at the pinnacle of creation, justifying the biblical concept of human dominion over the rest of nature.

However, this claim was never credible to anyone observing nature carefully. It was largely promoted by religious authorities to foster a sense of human uniqueness and importance. This, in turn, reinforced belief in a creator god, supported the authority of religious institutions and their clerics, and justified their claims to the right to create laws governing human behaviour.

Scientific research has increasingly exposed the fallacy of this notion of human exceptionalism. Tool-making and tool use in humans are indeed more sophisticated than in other animals, but this ability is far from unique. Many other species demonstrate these abilities, notably chimpanzees—our closest living relatives. The widespread occurrence of tool use in nature strongly suggests this trait was present in a common ancestor we share with other primates. Furthermore, the independent evolution of tool use in species as diverse as birds, bees, and octopuses demonstrates that this capability is not unique to humans but rather a result of natural evolutionary processes.

Another human characteristic, traditionally cited by religious authorities as evidence for special creation and human exceptionalism, has, once again, been shown by science to be better explained as evidence of our evolutionary heritage within the natural world.

And today we have evidence that chimpanzees not only make and use tools but employ sophisticated 'engineering' skill in their choice of the right materials for their construction. It comes in the form of a paper published, open access, in iScience by a team of researchers led by Dr Alejandra Pascual-Garrido, of the School of Anthropology and Museum Ethnography, University of Oxford, UK.

The Unintelligent Designer - Another Error-Prone Bungle to Compensate for a Bungled Design

William Heath Robinson

Peacekeeper cells protect the body from autoimmunity during infection | Biological Sciences Division | The University of Chicago

A significant issue with our immune system is that it is poorly "designed." If it were truly the product of an intelligent designer, as creationists claim, that designer would hardly be competent enough to design a simple household item, let alone a complex biological system.

Because our immune system is so disorganized and inefficient, multiple layers of complexity have evolved to mitigate its worst shortcomings. However, these added layers themselves remain prone to errors, as they reflect the same flawed foundation. The central problem arises because the immune system must balance two contradictory requirements: it needs to be sensitive enough to identify and eliminate genuine threats, yet not so sensitive that it mistakenly attacks the body's own tissues.

While an omnipotent, supremely intelligent designer should have easily resolved such a contradiction, the reality is that our immune system frequently fails on both counts. It often permits pathogens and parasites to invade, and it also frequently turns against the body itself, leading to autoimmune diseases such as lupus, diabetes, multiple sclerosis, arthritis, and kidney or liver failure, among numerous other debilitating conditions that cause immense suffering.

Like the whimsical contraptions created by cartoonist William Heath Robinson — complex machines built from objects originally intended for entirely different purposes - the mammalian immune system is not designed top-down from a clear blueprint. Rather, it's built up gradually from one makeshift adaptation piled onto another, each new solution attempting to compensate for the shortcomings of earlier ones. Eventually, this process results in a ramshackle system so intricate that its complexity itself creates new opportunities for failure. Such complexity is not indicative of intelligent, purposeful design, which would typically favour simplicity and efficiency. Instead, it reflects an ad hoc, utilitarian approach driven by evolutionary constraints and an inability to anticipate future challenges.

And of course, this embarrassment for creationism is made worse by the fact that, according to Michael J. Behe, pathogenic parasites such as E. coli and Plasmodium falciparum are examples of irreducible complexity, so are, in creationist circles, unarguable 'proof' of intelligent design, so the immune system is allegedly designed by the designer of these pathogens to protect us from them.

It seems creationists have no difficulty in believing the same designer would design parasites to make sick, then design a system to protect us from its pathogenic designs, and even though that system doesn't work very well, it is nevertheless evidence of supreme intelligence.

Refuting Creationism - LECA Was An Asgard Archaea

An artist’s depiction of an Asgard archaeon, based on cryo-electron tomography data: the cell body and appendages feature thread-like skeletal structures, similar to those found in complex cells with nuclei.

Graphic: Margot Riggi,
Max Planck Institute of Biochemistry

Asgard tubulin.

Origin of Life: How microbes laid the foundation for complex cells | ETH Zurich

Recent research indicates that the last universal common ancestor of complex (eukaryotic) cells, which encompass all multicellular plant and animal life, likely originated from the Asgard group of archaea. This ancestor is believed to have formed a symbiotic relationship with an alphaproteobacterium, which eventually evolved into the mitochondrion.

The initial nature of this symbiotic relationship—whether parasitic or predatory—remains uncertain. However, its establishment was pivotal in setting the evolutionary course that led to the diversity of life on Earth. Compelling evidence supporting the Asgard archaea hypothesis has been uncovered by Professor Martin Pilhofer and his team at the Eidgenössische Technische Hochschule (ETH) Zurich, Switzerland. Their findings have been published in the journal Cell and is explained in an ETH news item by Peter Rüegg:

What Our Prophets Never Told Us - Because Our Prophets Hadn't Got A Clue

Euclid’s view of the Cat’s Eye Nebula

ESA - Euclid opens data treasure trove, offers glimpse of deep fields

A point I never tire of making because it contrasts so vividly what the authors of the Bible thought the Universe was like and what science is showing us it is really like, is the ludicrously naive description of a small, flat planet with a dome over it, with the moon, sun and starts attached to the dome.

Don't take my word for it. Open your Bible and read the first few pages:

And God said, Let there be a firmament in the midst of the waters, and let it divide the waters from the waters. And God made the firmament, and divided the waters which were under the firmament from the waters which were above the firmament: and it was so. And God called the firmament Heaven. And the evening and the morning were the second day. And God said, Let the waters under the heaven be gathered together unto one place, and let the dry land appear: and it was so. And God called the dry land Earth; and the gathering together of the waters called he Seas: and God saw that it was good. (Genesis 1.6-10)

And God made two great lights; the greater light to rule the day, and the lesser light to rule the night: he made the stars also. And God set them in the firmament of the heaven to give light upon the earth, And to rule over the day and over the night, and to divide the light from the darkness: and God saw that it was good.(Genesis 1.16-18)

How the Bible's authors saw the Universe.

Now compare that with the view of just a small fragment of the universe that the European Space Agency's space telescope, Euclid, has revealed today:

Unintelligent Design - How 'Selfish' Genes Can Act Like Killer Parasites

Fluorescent microscopy images of highly variable wtf genes’ poison proteins (Wtf^poison) exhibit similar aggregation and distribution within yeast cells.

Graphical illustration showing rules for effective and ineffective neutralization of poison proteins. Yeast cells are “rescued” when wtf^poison and wft^antidote specifically co-assemble and localize toward the vacuole (left panel). Otherwise, yeast cells are destroyed (right panels).

Stowers scientists uncover… | Stowers Institute for Medical Research

As Richard Dawkins explained in his influential book, The Selfish Gene, all genes can be thought of as "selfish" in the sense that natural selection favours those most effective at surviving and replicating. Such genes persist over generations at the expense of rival alleles. Even when genes form cooperative alliances, as they commonly do, it ultimately serves their own evolutionary success. Of course, genes are merely chemical entities - mindless, emotionless, and incapable of intention or planning - so the concept of "selfishness" is simply a metaphor designed to illustrate gene-cantered evolution.

However, within the genomes of many multicellular organisms, certain genes can more literally be described as selfish. These genes act parasitically, exploiting the host cell’s replication machinery solely to propagate themselves, despite having no beneficial function and often harming their host by reducing its fertility. The mechanisms behind this parasitic behaviour have puzzled scientists since these genes were first discovered.

Refuting Creationism - Our Ancestry In Africa Was More Complex Than We Thought

Early Homo sapiens in Africa

AI-generated image (ChatGPT4.5)

Plaster reconstructions of the skulls of human ancestors

Jose A. Bernat Bacete via Getty Images

Genetic study reveals hidden chapter in human evolution | University of Cambridge

Traditionally, creationists have been fascinated by complexity, wrongly assuming that intricate biological systems are definitive evidence of intelligent design. In reality, simplicity is typically a hallmark of efficient, intelligent design, whereas complexity often emerges from evolutionary processes that accumulate layers of adaptation, frequently to compensate for earlier suboptimal features.

However, one particular form of complexity is likely to provoke considerable confusion among creationists: the evolutionary history of our own species in Africa. Once imagined as a straightforward, linear progression - from Australopithecines through transitional species like Homo erectus, which then migrated out of Africa into Eurasia - the true narrative has proven far more intricate. Homo sapiens evolved within Africa, and subsequently some populations ventured into Eurasia, encountering and interbreeding with the descendants of earlier migrations, notably Neanderthals and Denisovans, who had evolved independently from Homo erectus.

Given our species' propensity to interbreed with closely related hominins - likely facilitated by sexual activity serving recreational and social bonding purposes alongside procreation, a trait possibly shared by our ancestral and cousin species - recent research indicates a highly complex evolutionary pattern. Rather than a simple linear progression, the evolution of humans involved multiple episodes of diversification, genetic isolation, subsequent renewed contact, and interbreeding within Africa's vast landscapes, creating a rich mosaic of genetic heritage.

Refuting Creationism - How Chimpanzees Have Evolved For Different Parasites, Including Malaria

Mother and baby chimpanzee in Uganda.

Kevin Langergraber, The Ngogo Chimpanzee Project.

Chimpanzees are genetically adapted to local habitats and infections such as malaria | UCL News - UCL – University College London

It can't be easy making a living as a creationist grifter when science continually undermines your claims, exposing your misrepresentation of evolutionary biology and eroding your credibility — even among the faithful supporters you count on to pay for confirmation of their biases. It must be a relief that your target will rarely, if ever fact check your claims, making them easy victims of your disinformation.

So, you can take comfort in the fact that none of your marks will read this piece of research that shows how chimpanzees are closely related to humans and have evolved over time to adapt to a number of different environments, much the way the ancestors of modern humans adapted when their environment changed from forest to savannah, some 6 million years ago.

Included in the study is how chimpanzees, who have been suffering from malaria for much longer than humans, humans having acquired their most deadly species of the plasmodium parasites from chimpanzees only some 300,000 years ago and possibly as recently as 50,000 years ago, have evolved resistance to the parasite so they now show almost no signs of infection.

Malevolent Design - How a Design Blunder Caused Parkinson's Disease - Or Was It Malevolence?

Two PINK1 proteins are shown attached to the membrane of a mitochondrion for the first time.

Scientists solve decades-long Parkinson’s mystery | WEHI

One of the causes of Parkinsonism is the accumulation of defective mitochondria in neurone leading to the death of these cells and reduced neurotransmitter production. Under normal circumstances, a protein known as PTEN-induced putative kinase 1 (PINK1) attaches to the surface of damaged mitochondria and facilitates their destruction, but when a mutation causes PINK1 to malfunction, this cell hygiene mechanism fails.

The question for creationists is why this cell hygiene process is needed in the first place when an intelligent designer could have designed more robust mitochondria, and why does it depend on an error-prone process where a simple mutation is the gene for a key protein can cause the whole thing to fail?

In fact, of course, what we have here is an example of a layer of complexity being necessary because a fundamental process is suboptimal, when a well-designed process would need no such additional layer of complexity. Additional complexity simply multiplies that opportunity for failure, especially when the additional complexity is itself suboptimal.

As an example of putative intelligent design, the result is exactly what we would expect a mindless, unintelligent process to produce.

Refuting Creationism - Common Ancestry Of Mosses and Algae - 600 Million Years Before 'Creation Week'.

The star-shaped algae Zygnema circumcarinatum shows similar stress reactions to the moss

Photo: Tatyana Darienko

The branching moss Physcomitrium patens, which the researchers used to study stress reactions and compare them to algae.

Photo: Tatyana Darienko.

600 million years of stress: plants retain shared gene hubs - Georg-August-Universität Göttingen

Like animals, plant life originated in the sea and only colonized land once they evolved the necessary adaptations. For animals, this meant developing mechanisms for breathing air and terrestrial locomotion. For plants, the primary challenge was desiccation, creating strong selection pressure for traits that mitigated water loss. This led to the evolution of a highly connected network of genes, known as a 'hub,' that regulates responses to environmental stress.

So fundamental is this genetic hub to plant survival that it has remained highly conserved throughout evolutionary history.

What information do you have on the evidence for the evolution of land plants and their divergence from marine algae? The evolution of land plants from their algal ancestors is one of the most significant transitions in Earth's history. Multiple lines of evidence, including molecular phylogenetics, comparative genomics, palaeobotany, and developmental biology, support the hypothesis that land plants (embryophytes) evolved from a group of green algae, specifically within the Charophyte clade. Below is a summary of the key evidence:

1. Molecular and Phylogenetic Evidence
   • Shared Genetic Markers: Molecular phylogenetic studies show that land plants are most closely related to charophyte algae, such as Chara and Klebsormidium.
   • Chloroplast DNA Similarities: Land plants and charophytes share specific gene arrangements in their chloroplast DNA, supporting common ancestry.
   • Cellulose Synthase Genes: The enzyme responsible for cellulose biosynthesis (CesA) has similar genetic sequences in charophytes and land plants.
   • Regulatory Genes: Some transcription factors crucial for land plant development, such as KNOX and BELL genes, have homologs in charophyte algae.
2. Morphological and Structural Evidence
   • Cell Division Similarities: Charophyte algae and land plants share a phragmoplast-based cell division mechanism, distinct from other algal groups.
   • Sporopollenin Protection: Spores of early land plants and some charophytes are encased in sporopollenin, a tough biopolymer that protects against desiccation.
   • Plasmodesmata: Both groups have plasmodesmata, cell-to-cell communication channels that enable coordinated growth.
   • Branching Growth: Some charophyte algae, such as Coleochaete, show apical growth similar to land plants.
3. Fossil Evidence
   • Ordovician and Silurian Microfossils (470-440 Ma): Fossilized spores with sporopollenin coatings appear before macroscopic land plant fossils, indicating early adaptation to terrestrial environments.
   • Rhynie Chert (Early Devonian, ~407 Ma): Preserves some of the earliest land plants (Rhynia, Aglaophyton), showing vascular tissue development.
   • Cooksonia (Silurian-Devonian Transition, ~430-410 Ma): One of the earliest known vascular plants, showing transition from bryophyte-like ancestors to tracheophytes.
4. Biochemical and Physiological Adaptations
   • Desiccation Tolerance: Early land plants and some charophytes can survive drying out, an adaptation to terrestrial life.
   • Hormonal Pathways: Land plants and charophytes use similar hormones, such as auxin and abscisic acid, for growth and stress response.
   • Symbiosis with Fungi: Fossil evidence and molecular studies suggest that early land plants formed mutualistic associations with mycorrhizal fungi (Glomeromycota) to obtain nutrients.
5. Transitional Forms
   • Zygnematophyceae as a Key Group: Recent genomic studies suggest that the Zygnematophyceae, a subgroup of charophyte algae, are the closest relatives of land plants. These algae lack complex multicellularity but share stress tolerance genes with land plants.
   • From Simple Algae to Complex Embryophytes: Gradual increase in structural complexity, from filamentous and parenchymatous algae to early non-vascular land plants, suggests a stepwise transition to terrestrial life.

Conclusion

The divergence of land plants from marine algae is well-supported by multiple independent lines of evidence. The transition was driven by adaptations to terrestrial challenges such as desiccation, nutrient acquisition, and reproduction. The evolutionary path likely involved early colonization by freshwater charophyte algae, which evolved desiccation tolerance, protective spores, and symbiotic relationships that facilitated the transition to permanent land-based life.

Now a team of researchers from Georg-August-Universität, Göttingen, Germany, led by Professor Jan de Vries, Göttingen University, who led the research, explains: has shown that this same 'hub' is present in both mosses and algae, even though they diverged 600 million years ago, the mosses having evolved out of simple algae.

Refuting Creationism - A Fossil Mammal From 62-Million-Years Before 'Creation Week'

Mixodectes pungens (foreground), small mammals that inhabited western North America 62 million years ago, weighed about 3 pounds, dwelled in trees, and largely dined on leaves. They inhabited the same forests as early primates like Torrejonia wilsoni (background).

Illustration by Andrey Atuchin.

A 62-million-year-old skeleton sheds light on an enigmatic mammal | Yale News

Sometimes, I almost feel sorry for creationists struggling to cling to their childish counter-factual superstition in the face of this constant deluge of contrary scientific evidence. Then I realise they are architects of their own defeat by consciously and conscientiously ignoring this contrary evidence. Remaining ignorant and so remaining wrong is a choice that they don't have to choose just to maintain the self-delusion that they are more expert than the experts.

So, I have no conscience about reporting yet another example of incontrovertible evidence of evolution on an Earth which is much older than creationists prefer to believe. It comes in the form of a reassessment of a 65-million-year-old fossil of an early mammal from the same branch of the evolutionary tree as primate, so is a distant cousin on humans.

Refuting Creationism - A Mass Extinction 252 Million Years Before 'Creation Week' - And Why Some Survived It

The End-Permian Mass Extinction

Ai-Generated Image (ChatGPT4)

Mastodonsaurus

Image: Mark P. Witton

March: Amphibians bounce-back from Earth’s greatest mass extinction | News and features | University of Bristol

The thing about mass extinctions, apart from the fact that they occurred so long before creationists dogma says there was even a universe, is that they refute any notions of a planet fine-tuned for life, or any notions of a perfect creator creating all life as it is today. In fact, it was the growing interest in palaeontology and the growing realisation that the fossil record contained so many extinct species, which caused people to start to question the notion of divine creation by a perfect god.

It was also the existence of so many intermediate fossils and series showing progressive change over time that fostered the idea of evolutionary change, although, until Darwin and Wallace thought of evolution by natural selection, how it worked was a matter of speculation.

The end-Permian mass extinction was one of the most significant events in the history of life on Earth - a history, 99.9975% of which occurred before creationists think their little god created the small flat planet with a dome over it in the Middle East, that creationists like to imagine was the entire universe.

However, fortunately for subsequent life on the planet, and without whom it is unlikely that humans would exist, a handful of species survived, most notably some amphibians.