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In a striking demonstration of the theory of evolution in practice — and something that will have creationists once again insisting on redefining evolution as a theory about one creature turning into an entirely unrelated taxon — an experiment aboard the International Space Station has shown how subtle changes in the environment can dramatically alter an evolutionary trajectory. It also illustrates another major embarrassment for Intelligent Design creationists: evolutionary arms races. Arms races are, of course, utterly incompatible with the idea of an intelligent designer, since running to stand still in a race with yourself is a neat definition of insanity.
Unlike the creationist parody of evolution — carefully engineered to be unprovable because it does not describe what actually happens and what no biologist has ever claimed — the real scientific definition of evolution is simply a change in the frequency of different alleles in a population over time. A definition that creationists know to be irrefutable, hence their persistent attempts to redefine it so that they have something to attack.
The experiment, which had a parallel control on Earth, was designed to observe how bacteriophage viruses that parasitise bacteria and their hosts co-evolved in the microgravity environment of space.
The results have just been published in PLOS Biology. They show that both the T7 phage virus and the E. coli bacteria developed marked genomic differences compared with the Earth-bound populations. The space-station phages gradually accumulated specific mutations that enhanced infectivity or improved their ability to bind receptors on bacterial cells. Meanwhile, the space-station E. coli accumulated mutations that improved resistance to phages and enhanced survival in near-weightless conditions. In other words, what was observed was a genuine evolutionary arms race — and because the environments differed between the space-station populations and the Earth-bound populations, the divergence can be attributed directly to differences in gravity.
The results highlighted another intriguing angle: the mutations that phages and bacteria acquire in space don’t just reveal fundamental evolutionary dynamics, they can also have practical applications for human health on Earth. After 25 days aboard the ISS, both organisms returned with novel mutations not commonly seen under terrestrial gravity, including changes to bacterial surface proteins and corresponding phage adaptations to bind those altered surfaces.
Researchers then engineered phages carrying these space-derived mutations and tested them against bacterial pathogens responsible for urinary tract infections — many of which are now resistant to antibiotics — finding the space-influenced phages were notably effective at killing these otherwise resistant strains. This suggests that the unique selection pressures of microgravity may reveal evolutionary pathways that could be harnessed to design improved therapies for antibiotic-resistant infections back on Earth.














































