Thursday, 11 March 2021

Malevolent Designer News - Making SARS-CoV-2 a Better Killer

With the new variant already detected in more than 50 countries worldwide, the analysis provides crucial information to governments and health officials to help prevent its spread.
Research news - Variant B.1.1.7 of COVID-19 associated with a significantly higher mortality rate, research shows - University of Exeter

News today that should thrill every devoted worshiper of the supposed creator deity who made the SARS-CoV-2 virus to kill us with!

Research "by epidemiologists from the Universities of Exeter and Bristol, has shown that the SARS-CoV-2 variant, B.1.1.7, is associated with a significantly higher mortality rate amongst adults diagnosed in the community compared to previously circulating strains."

So, from the point of view of someone who believes in intelligent [sic] design, where nothing evolves and everything is the deliberate result of design by this creative deity, it looks like this designer was quick to produce a new modification, almost immediately human medical science seems to have come up with a vaccine that gave us the ability to defend ourselves from its deadly creation.

This from the University of Exeter press release:

Variant B.1.1.7 of COVID-19 associated with a significantly higher mortality rate, research shows


The highly infectious variant of COVID-19 discovered in Kent, which swept across the UK last year before spreading worldwide, is between 30 and 100 per cent more deadly than previous strains, new analysis has shown.

In the community, death from COVID-19 is still a rare event, but the B.1.1.7 variant raises the risk. Coupled with its ability to spread rapidly this makes B.1.1.7 a threat that should be taken seriously.

Dr. Robert Challen, Lead author
Postdoctoral research associate
College of Engineering, Mathematics and Physical Sciences,
University of Exeter, Exeter, UK
A pivotal study, by epidemiologists from the Universities of Exeter and Bristol, has shown that the SARS-CoV-2 variant, B.1.1.7, is associated with a significantly higher mortality rate amongst adults diagnosed in the community compared to previously circulating strains.

The study compared death rates among people infected with the new variant and those infected with other strains.

It showed that the new variant led to 227 deaths in a sample of 54906 patients – compared to 141 amongst the same number of closely matched patients who had the previous strains.

We focussed our analysis on cases that occurred between November 2020 and January 2021, when both the old variants and the new variant were present in the UK. This meant we were able to maximise the number of “matches” and reduce the impact of other biases. Subsequent analyses have confirmed our results.

SARS-CoV-2 appears able to mutate quickly, and there is a real concern that other variants will arise with resistance to rapidly rolled out vaccines. Monitoring for new variants as they arise, measuring their characteristics and acting appropriately needs to be a key part of the public health response in the future.

Professor Leon Danon, Senior author
Associate professor in infectious disease epidemiology and data analytics
Bristol Medical School, Population Health Sciences
University of Bristol, Bristol, UK
With the new variant already detected in more than 50 countries worldwide, the analysis provides crucial information to governments and health officials to help prevent its spread.

The study is published in the British Medical Journal on Wednesday, 10 March 2021.

Robert Challen, lead author of the study from the University of Exeter said: “In the community, death from COVID-19 is still a rare event, but the B.1.1.7 variant raises the risk. Coupled with its ability to spread rapidly this makes B.1.1.7 a threat that should be taken seriously.”

The Kent variant, first detected in the UK in September 2020, has been identified as being significantly quicker and easier to spread, and was behind the introduction of new lockdown rules across the UK from January.

The study shows that the higher transmissibility of the Kent strain meant that more people who would have previously been considered low risk were hospitalised with the newer variant.

Having analysed data from 54609 matched pairs of patients of all age-groups and demographics, and differing only in strain detected, the team found that there were 227 deaths attributed to the new strain, compared to 141 attributable to earlier strains.

It was fortunate the mutation happened in a part of the genome covered by routine testing. Future mutations could arise and spread unchecked

Ellen Brooks-Pollock, Co-author
Senior lecturer in veterinary public health
University of Bristol, Bristol Veterinary School, Langford, Bristol, UK
Leon Danon, senior author of the study from the University of Bristol said: “We focussed our analysis on cases that occurred between November 2020 and January 2021, when both the old variants and the new variant were present in the UK. This meant we were able to maximise the number of “matches” and reduce the impact of other biases. Subsequent analyses have confirmed our results.

“SARS-CoV-2 appears able to mutate quickly, and there is a real concern that other variants will arise with resistance to rapidly rolled out vaccines. Monitoring for new variants as they arise, measuring their characteristics and acting appropriately needs to be a key part of the public health response in the future.”

Ellen Brooks-Pollock from the University of Bristol expanded: “It was fortunate the mutation happened in a part of the genome covered by routine testing. Future mutations could arise and spread unchecked”.
The group's research was published open access yesterday in the BMJ:

Abstract


Objective To establish whether there is any change in mortality from infection with a new variant of SARS-CoV-2, designated a variant of concern (VOC-2020
12/1) in December 2020, compared with circulating SARS-CoV-2 variants.

Design Matched cohort study.

Setting Community based (pillar 2) covid-19 testing centres in the UK using the TaqPath assay (a proxy measure of VOC-202012/1 infection).

Participants 54 906 matched pairs of participants who tested positive for SARS-CoV-2 in pillar 2 between 1 October 2020 and 29 January 2021, followed-up until 12 February 2021. Participants were matched on age, sex, ethnicity, index of multiple deprivation, lower tier local authority region, and sample date of positive specimens, and differed only by detectability of the spike protein gene using the TaqPath assay.

Main outcome measure Death within 28 days of the first positive SARS-CoV-2 test result.

Results The mortality hazard ratio associated with infection with VOC-202012/1 compared with infection with previously circulating variants was 1.64 (95% confidence interval 1.32 to 2.04) in patients who tested positive for covid-19 in the community. In this comparatively low risk group, this represents an increase in deaths from 2.5 to 4.1 per 1000 detected cases.

Conclusions The probability that the risk of mortality is increased by infection with VOC-202012/01 is high. If this finding is generalisable to other populations, infection with VOC-202012/1 has the potential to cause substantial additional mortality compared with previously circulating variants. Healthcare capacity planning and national and international control policies are all impacted by this finding, with increased mortality lending weight to the argument that further coordinated and stringent measures are justified to reduce deaths from SARS-CoV-2.

It's obviously a measure of the acute embarrassment felt by the Creationism industry that (at least to my knowledge) not a single word has been uttered by any of the leaders of the movement or by the usual lickspittles of the Discovery Institute who invented the notion, on the subject of the coronavirus pandemic and how the origin and evolution of the SARS-CoV-2 virus fits into their preferred model of reality - where everything is the result of intentional design by a magic designer deity (who just happens to be identical to the god of the Christian Bible), and thus where the Bible's creation narrative is literally true.

Even when I have tried to raise this problem in online Creationist chat groups I have been met only with abuse and swiftly shown the door. Not a single Creationist has ever faced up to this problem and tackled it head on. The coronavirus pandemic is the stinking elephant turd in the middle of their room that continues to be ignored. So, in the full expectation of being ignored yet again, I'll ask again:

Why is evolution by natural selection the only explanation for the SARS-CoV-2 virus that doesn't make Creationism's putative designer god look like a pestilential, genocidal, misanthropic sadist who hates its creation and wishes to make it suffer and die?










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