Evolution In Progress - How Honey Bees Are Evolving - Another Move In The Arms Race

Southern California hybrid honeybee hive hanging from a tree in the wild.

Boris Baer/UCR

Varroa destructor on a honeybee

Jon Gascoyne/Flickr

SoCal honeybees can fend off deadly mites | UCR News | UC Riverside

A new paper in Scientific Reports by Genesis Chong-Echavez and Boris Baer of the University of California, Riverside, casually refutes creationism by showing evolution in progress. It describes how honeybees, Apis mellifera, are evolving to survive in the presence of a serious parasite, the Varroa mite, Varroa destructor. And, no doubt to the consternation of any creationists who understand the implications, it also illustrates how evolutionary arms races are a major driver of adaptation. Both parasites and arms races are deeply embarrassing for creationism because they make little sense as the products of an intelligent designer. Indeed, parasites conform to the Discovery Institute’s supposed “proof” of intelligent design only if that designer is malevolent; yet if parasites are dismissed as evidence of design, creationists are simply abandoning one of their own favourite arguments.

In other words, a parasite-host arms race is a paradox that creationism cannot resolve, whereas evolutionary theory not only explains it, but is strengthened by it. The paper concerns a Southern Californian hybrid population of honeybees with ancestry from Western European, Eastern European, Middle Eastern, and African lineages. These bees are showing resistance to the Varroa mite, a parasite that has played a major role in the catastrophic losses of managed honeybee colonies in the United States, where beekeepers reported losses of up to 62% in 2025.

The researchers monitored 236 colonies over four years and found that the Californian hybrid colonies consistently had lower mite infestation rates than colonies headed by commercial queens. In the UCR summary of the work, the hybrid colonies are described as having about 68% fewer mites on average and as being more than five times less likely to cross the treatment threshold at which chemical control becomes necessary. Laboratory experiments also showed that the mites were less attracted to larvae from these hybrid bees, especially at the stage when mites would normally be most likely to invade brood cells.

The usual creationist response to examples like this is to retreat into a parody definition of evolution involving a change in “kind”, with “kind” carefully left undefined, or to fall back on Bible-literalist theology and explain parasites as the result of “sin”, by some unexplained mechanism against which their creator appears curiously powerless. But the problem of arms races remains. On that view, creationism’s single designer seems to be competing with itself, continually redesigning solutions to problems of its own making, ad infinitum. Evolutionary biology, by contrast, has no such difficulty. It predicts exactly this kind of reciprocal adaptation between parasite and host.

Malevolent Design - A Parasitic Fly With All Creationism's Hall Marks for Intelligent Design Is Heading For The USA

Lava of the New World screwworm, Cochliomyia hominivorax.

By John Kucharski - via Wikipedia

The New World screwworm, Cochliomyia hominivorax.

Judy Gallagher, CC BY

An article in The Conversation by Richard Wall, Emeritus Professor in the School of Biological Sciences at the University of Bristol, should remind creationists—if they had the wit to understand why—of the theological quagmire into which their favourite leaders have led them.

The Discovery Institute and its fellows, with their reliance on notions such as irreducible complexity and complex specified genetic information, have taken creationism to a point where the only escape lies in three almost equally unacceptable options:

• They can abandon the very arguments they present as proof of intelligent design, and so admit that they have no proof at all.
• They can accept that the designer god they traditionally equate with the god of the Bible and Qur'an is in fact an evil god, relentlessly designing ever more ingenious ways to increase suffering in the world.
• Or they can retreat into theology and Bible-literalist fundamentalism, abandoning any pretence that intelligent design is genuine science rather than simply rebranded creationism, by blaming everything on 'The Fall'. But in doing so they must also admit the existence of some other creative force with powers sufficient to rival their creator god—one to which their god is either powerless or indifferent. That, of course, destroys the basic principle of Judeo-Christian monotheism: a single omnipotent ruling deity. Ironically, the Discovery Institute was established for the very purpose of persuading US legislators and state education officials that intelligent design is real science.

This problem for creationism arises because the notions of irreducible complexity and complex specified genetic information apply just as well—if not better—to parasites and pathogens as they do to those aspects of nature that creationists like to present as evidence of their god's existence and benevolence; in other words, anything that happens to benefit them.

Professor Wall's article concerns a parasitic fly, the New World screwworm, Cochliomyia hominivorax, whose larvae feed on open wounds in cattle and sometimes humans, often with fatal consequences. The fly is currently extending its range northwards through Mexico and has now reached states bordering Texas. His article is reproduced here under a Creative Commons licence, reformatted for stylistic consistency:

Refuting Creationistm - An Evolutionary Trap That No Intelligent Designer Would Blunder Into

Sceptobius beetles in an ant colony

The evolutionary trap that keeps rove beetles alive

A new study reported in Cell describes an extraordinary example of evolutionary adaptation unfolding right under our noses — and it will make uncomfortable reading for anyone still clinging to the creationist fantasy that living systems were neatly “designed” in their present form a few thousand years ago.

Researchers from the Division of Biology and Biological Engineering, California Institute of Technology, CA. USA, investigating the symbiotic relationship between certain rove beetles and their ant hosts have shown how these beetles have evolved the ability to infiltrate ant colonies by chemically disguising themselves as ants. Far from being “created” to live harmoniously together, this is an evolutionary arms-race in miniature: ants have evolved sophisticated chemical recognition systems to detect intruders, while the beetles have evolved equally sophisticated counter-measures to bypass those defences.

And the details are exactly the sort of thing intelligent design advocates never seem to anticipate. The beetles do not simply possess some magical, pre-installed “ant colony access” trait. Instead, evolution has shaped them into something far stranger and far less tidy: they suppress their own scent production and acquire the colony’s chemical signature directly from the ants themselves. In effect, they become living imposters — accepted not because the ants were “meant” to host them, but because natural selection has honed the beetles’ ability to exploit a biological loophole.

Malevolent Design - The Malaria Parasite Is Irreducibly Complex And Has Complex Specified Genetic Information - Oops!

Blood smear showing P. falciparum parasites.

CDC/Dr. Mae Melvin Transwiki approved by: w:en:User:Dmcdevit
This media comes from the Centers for Disease Control and Prevention's
Public Health Image Library (PHIL), ID #2704
Public Domain, Link

Malaria: Newly Identified “Crown” Stage Controls Parasite Reproduction

Researchers from the Hebrew University of Jerusalem have uncovered yet another layer of exquisite molecular sophistication in one of humanity’s most persistent and lethal parasites, Plasmodium falciparum, the chief cause of malignant malaria. Their findings, reported in a recent press release and published in the peer-reviewed Journal of Cell Biology, describe a newly identified regulatory “crown” checkpoint that controls parasite reproduction with remarkable precision.

It is difficult to imagine a discovery more awkward for Intelligent Design creationists, because Plasmodium falciparum is precisely the sort of organism that embodies everything Michael Behe and William Dembski insist cannot arise by evolution. Here is complex specified genetic information, tightly regulated developmental choreography, and interlocking biochemical machinery operating across multiple life stages — the very definition, we are told, of “irreducible complexity”.

Unfortunately for the Discovery Institute, this irreducible complexity does not produce a bird’s wing, a human eye, or some uplifting example of divine craftsmanship. It produces malaria — a parasite responsible for immense suffering and hundreds of thousands of deaths every year, mostly children. If complexity is meant to be a hallmark of intelligent design, then the designer’s portfolio includes some rather grim specialities.

The problem is compounded by the fact that Michael Behe has already made malaria central to his arguments. In The Edge of Evolution, he famously pointed to the parasite’s resistance to anti-malarial drugs as an example of the supposed limits of Darwinian evolution, claiming that multiple coordinated mutations were beyond the reach of natural selection. Yet malaria has since become one of the clearest demonstrations that evolution not only occurs, but does so rapidly and repeatedly, exploiting enormous population sizes and intense selection pressures to produce exactly the adaptations Behe claimed were improbable.

As Kenneth Miller pointed out, Behe's mathematical sleight of hand was to assume resistance had to evolve as a single event in a single cell, not across a large population over time - a fallacy of which any good microbiologists should have been aware.

This newly described “crown” stage is simply the latest reminder that biological complexity is not evidence of supernatural design. Evolution predicts complexity wherever it confers survival advantage — including in parasites, pathogens, and diseases. The only real surprise is that creationists continue to present complexity as a theological virtue, when nature so often deploys it in the service of exploitation rather than benevolence.

As ever, none of this will deter creationists from repeating their familiar articles of faith. Faced with an organism whose life cycle resembles a biochemical symphony — regulated checkpoints, specialised invasion machinery, host-cell remodelling, immune evasion, and reproductive stages split between mosquito and human — they will insist that this is not evidence for evolution but evidence against it. The argument, such as it is, runs that complexity must have been present from the start, because it could not have arisen gradually.

But this is simply the old “irreducible complexity” claim in a new disguise: the assertion that because creationists personally cannot imagine intermediate stages, no such stages could have existed. Science, of course, is not obliged to conform to the limits of anyone’s imagination. Evolution does not require that complex systems appear in a single leap. It proceeds by modification of what already exists — co-option, duplication, repurposing, and incremental refinement over deep time — producing the layered complexity we observe today.

Another common retreat is the insistence that this is merely “microevolution”, the trivial shuffling of genes within some mythical created “kind”. Yet Plasmodium falciparum is not merely adjusting the colour of its spots. It is evolving novel biochemical strategies, repeatedly acquiring drug resistance, fine-tuning developmental regulation, and exploiting host environments with extraordinary efficiency. If this is “only microevolution”, then the term has been drained of all meaning.

Malevolent Design - How The Toxoplasma Parasite Looks Intelligently Designed - To A Creationist

Toxoplasma gondii cyst in brain cell.

A) Toxoplasma gondii tachyzoites, the rapidly multiplying form of the parasite. B) A bradyzoite cyst containing Toxoplasma gondii within a muscle fiber, showing the cyst wall and individual bradyzoites. C) Histological section of tissue with Toxoplasma gondii cysts. D) Microscopic image of a Toxoplasma gondii oocyst, responsible for environmental transmission.

source.

Scientists find hidden diversity inside common brain parasite | UCR News | UC Riverside

Another example of a nasty little parasite that bears all the hallmarks of the Discovery Institute’s supposed *“proof”* of intelligent design was unveiled today, when scientists from the University of California, Riverside published the results of their investigation into the common brain parasite, Toxoplasma gondii, which infects up to a third of the global population. Their paper was published open access in Nature Communications. It has been released unedited to provide early access to the findings.

Ask Discovery Institute (DI) fellow Michael J. Behe for proof of intelligent design and he will produce multiple examples of what he terms “irreducible complexity”, claiming that such systems could not have evolved step by step and therefore must have been designed by a supernatural intelligent designer. Similarly, ask another DI fellow, William A. Dembski, for proof of intelligent design and he will produce examples of what he calls “complex specified genetic information”, which he claims likewise could not have evolved naturally and therefore must have been provided by a supernatural designer.

Curiously, however, when biologists point to examples of “irreducible complexity” or “complex specified genetic information” in pathogens or parasites — organisms whose sole apparent purpose is to make us ill or kill us, or at the very least to increase suffering in the world - as evidence that, if the ID creationists’ argument were granted, it would imply malevolent intent on the part of the intelligent designer, the response is either silence or retreat into theology. More often than not, the blame is shifted to “the Fall”, while the insistence remains that intelligent design is a genuine scientific alternative to “Darwinism”, and not merely Bible-literalist Christian fundamentalism under another name.

At this point, their supposed “proof” of intelligent design quietly evaporates. Behe will even attempt to argue that the random process he calls “genetic entropy” is responsible, thereby conceding that random processes can generate what Dembski describes as complex specified genetic information — while simultaneously insisting that such information cannot have evolved through random processes at all.

The UC Riverside team have now shown that Toxoplasma gondii is even more complex than previously thought. It was already known that the parasite invades the brain and other tissues, where it forms dormant cysts that can later be reactivated. Its preferred hosts are members of the cat family, and humans are most commonly infected via cats. In some secondary hosts, it has been shown to manipulate behaviour in ways that make them more likely to be eaten by a cat, thereby completing its life cycle. Infected mice, for example, actively seek out the presence of domestic cats, while chimpanzees develop a fascination with the scent of leopard urine. It is possible that effects observed in humans are an echo of this behaviour-modifying mechanism inherited from our evolutionary past.

The new research shows that these cysts are far more complex than simple dormant copies of the parasite. Instead, they are intricate assemblages of multiple sub-types, each with distinct biological functions. In this respect, the cyst exhibits some of the characteristics of a multicellular organism, including a degree of cellular specialisation.

Unintelligent Design - Why Some People Suffer More From The Common Cold Than Others - Incompetent or Malevolent Design - Or Evolution?

Electron micrograph showing a human nasal epithelial cell releasing rhinovirus (blue).

Credit: Julien Amat, Bao Wang

Electron micrograph of differentiated human nasal epithelial organoids with cilia of multiciliated cells accentuated in blue.

Credit: Julien Amat, Bao Wang.

Why the same cold can be a sniffle for some and a crisis for others | Yale News

You might expect an intelligently designed system, created by an omnibenevolent designer, to work just as effectively for everybody and not badly for some and only just adequately for others. And yet, as so often with creationism, the facts are not at all what the theory predicts. In science this would be called falsification, but for creationists it is just another inconvenient fact to be ignored or blamed on ‘the Fall’ — or even on the victim.

According to a paper just published in Cell Press Blue, the reason some people suffer more from a cold caused by a rhinovirus is not so much because of differences in the virus, but because their bodies react differently. Some take control and prevent the spread of viruses to adjacent cells of the mucous membrane lining the nasal passages, whereas other people’s bodies fail to prevent the virus spreading.

The paper is by a team at Yale School of Medicine, New Haven, CT, USA, led by Associate Professor Dr Ellen F. Foxman, PhD.

By growing organoids in vitro and infecting them with rhinoviruses, the team were able to show that whether the infection spreads depends on how quickly the infected cells are able to mount an interferon response. A good response limits the infection to just a few cells and the cold does not develop beyond a ‘sniffle’. Where the response is weak, the infection spreads and, in cases where the victim has an underlying respiratory condition such as asthma or COPD, the cold can develop into a serious illness.

Why the interferon response differs between individuals is not known with any certainty, but it could be due to a number of factors, including genetics. However, it is known that in patients with pre-existing respiratory conditions, the interferon response is inhibited.

That, of course, begs the question for ID creationists: why a system supposedly designed to protect us gets downgraded when it is most needed, and, if the difference is due to underlying genetics, why some people got better genes in this respect than others. Under the ID creationist paradigm, genes that produce any given output are deemed to hold ‘complex specified genetic information’ and, as such, are evidence for intelligent design.

Leaving aside the question of why any omnibenevolent designer would design viruses to make us sick and then design an immune response to prevent them doing so, we are left with the question of why this immune system does not always work very well and why some people have a worse version than others. If an omnibenevolent designer can design an effective immune system, why did it not give it to everyone? Does it actually want those people to suffer more from the viruses it supposedly designed?

The evolutionary explanation is, of course, straightforward, with none of the theological conundrums that plague creationism. Evolution does not seek out perfection and has no interest in equity. In the environment of an evolutionary arms race with viruses, the results are inevitably suboptimal and unevenly distributed throughout the population unless there is particularly strong selection pressure to drive the ‘best’ solution to fixation. It is also in the survival interests of viruses to tone down their victim’s responses, thereby reducing that selection pressure. The resulting trade-off and compromise is what we see today in the different responses to the same virus.

Malevolent Design - Creationists Dogged By Parasites Again - Evolution or Malevolence?

Cross section of a dog's heart showing heartworm.

The University of Sydney

Ancient ‘spaghetti’ in dogs’ hearts reveals surprising origins of heartworm | EurekAlert!

An international team of researchers led by scientists at the University of Sydney, NSW, Australia, have just published a paper in Communications Biology which reshapes our understanding of a widespread canine parasitic nematode, the heartworm, Dirofilaria immitis. It is also more bad news for creationists, and for the intelligent design cult in particular.

In particular, the team have shown that this parasite has probably been co-evolving with dogs since before they were domesticated. It had previously been assumed that human activity was responsible for the spread of these worms.

Applying all the criteria traditionally cited by ID creationists as ‘proof’ of intelligent design, any designer of this parasite emerges as a grotesque malevolence determined to make dogs suffer. There is also the problem, for ID creationists, of clear evidence of a co-evolutionary arms race — the hallmark of mindless evolution and the antithesis of intelligent design.

Heartworms are complex organisms, with a complex life cycle involving both the primary host — dogs — and a vector — mosquitoes — all of which must be present for the parasite to survive, thus conforming neatly to Michael J. Behe’s supposed ‘evidence for intelligent design’: irreducible complexity. There is also evidence of resistance both to the dog’s immune system and, more recently, to the veterinary drugs used to treat the infection, conforming equally well to William A. Dembski’s proposed ‘evidence for intelligent design’: complex specified genetic information. So, within the ID paradigm, the conclusion becomes unavoidable — heartworms have been intelligently designed and are being actively redesigned in order to continue making dogs suffer and to stay ahead in their arms race with veterinary science.

But of course, the biological evidence shows that these parasites are the product of a co-evolutionary process in which neither magic nor intent were involved. Nematode genes have no concern for the suffering they cause, nor for whether their host lives or dies, so long as it survives long enough to pass the parasites on to the next generation of dogs.

Although the evidence conforms exactly to what the Theory of Evolution predicts — and evolution remains the most parsimonious explanation, absolving any deities of responsibility — for some inexplicable reason the ID cult would prefer people to believe that these, and thousands of other parasites, were the handiwork of their favourite deity, who thus emerges as a divine malevolence; a complete contrast to the supposedly omnibenevolent god of the holy books that creationists worship.

Refuting Creationism - Two Ancient Eurasians Carried Human Papillomavirus (HPV16) - Long Before 'Creation Week' and 'The Fall'

A facial reconstruction of Ötzi the Iceman.

Image credit: Reconstruction by Kennis © South Tyrol Museum of Archaeology, Foto Ochsenreiter

Ötzi the Iceman mummy carried a high-risk strain of HPV, research finds | Live Science

Palaeontologists at the Federal University of São Paulo, Brazil have analysed the DNA recovered from two ancient humans and discovered that they were both carriers of the Human Papillomavirus HPV16, a virus implicated in several cancers. They have presented their evidence, ahead of peer-reviewed publication in the pre-print server, bioRxiv.

The interesting thing from the point of view of virology is that this discovery shed considerable light on when HPV entered the human virome and commenced co-evolving with us, with one theory being that we acquired them from Neanderthals. From the point of view of creationists however, the news could scarcely be worse.

The first sample, obtained from the famous 'Ötzi the Iceman', the 5,300 year-old mummified body recovered from a glacier on the Italian-Austrian border, is probably not too much of a problem for creationists as it just about falls within the timeline of the Bible mythology, apart from the little problem of it being from before they believe the was a general reset of Earth's biosphere in a genocidal flood which would have destroyed the glacier and everything in it, so Ötzi should not have been there.

But, the second is a massive problem, since it was recovered from a leg of a man, Ust'-Ishim man, recovered from western Siberia and dated to 45,000 years BP - way before creationists believe Earth existed, and tens of thousands of years before the mythical 'Fall', when creationists believe viruses didn't exist. This specimen provided the oldest complete human genome so far recovered and the DNA contains the unmistakable genome of HPV16. Creationist mythology just keeps getting further and further from reality as exposed by science using real-world evidence.

Traditionally, creationists claim Earth is 6,000 - 10,000 years old and was created perfect in every way, with no deaths or diseases, so no viruses, parasites or pathogens, bodies that always functioned perfectly and genomes that never failed to replicate perfectly. Then, along came 'sin' which, by some mysterious process, was able to thwart the omnipotent creator god's perfect plan and create viruses and other pathogens and make perfect physiology begin to malfunction and genomes to fail to replicate perfectly, causing variations and genetic weaknesses, etc.

Why a reputedly omnipotent creator failed to anticipate the effects of 'sin' and make its creation robust enough to resist them is never explained, although, apparently, it provided immune systems in preparation for something that, although omniscient, and even claimed to have created 'evil' (Isiah 45:7), it then failed to anticipate. But, as though those myths aren't too ridiculous for any adult with even a basic education to believe, creationists have to continually think of ways to ignore the evidence and continue holding plainly absurd beliefs, under the child-like delusion that their ability to do so is a sign of strength.

The paper itself sets out to address a long-standing question in human virology: how long oncogenic human papillomaviruses have been associated with our species, and whether their origins lie in relatively recent cultural changes or deep evolutionary history.

Refuting Creationism - Another of Those 'Living Fossils' For Creationists To Misrepresent

Adult marine shell-boring spionid polychaete.

Vasily Radishevsky/
Far Eastern Branch of the Russian Academy of Sciences

Spionid traces on fossilized bivalve shells.

Javier Ortega-Hernandez/Harvard University.

Half-billion-year-old parasite still threatens shellfish | UCR News | UC Riverside

It’s Coelacanth time for creationist disinformers again.

Hilariously, I’ve known creationists claim that the 'fact' that coelacanths haven’t changed for 200 million years somehow proves the “evilutionists” are wrong and that Earth is only 6,000–10,000 years old. How they managed to examine the genome of a 200-million-year-old fossil remains a mystery, but DNA appears to play no part in a creationist’s definition of evolution.

So, for an alternative fallacious argument, here’s an even older fossil that’s still around today, apparently in much the same form as it was almost half a billion years ago. It’s a parasitic worm that attacks oysters. The details have just been published in the journal iScience by scientists led by University of California, Riverside palaeobiologist Karma Nanglu, with colleagues from Harvard.

The parasitic, soft-bodied bristle worm belongs to a group called the spionids. It’s common in today’s oceans and feeds on the shells of mussels and oysters, leaving a characteristic question mark-shaped track in their shells. Their parasitism doesn’t kill the shellfish but probably shortens their lifespan.

Malevolent Designer News - A Newly-Designed Way To Increase Suffering Is Having Major Success in Southern China

Chikungunya Virus Replication Cycle

BioRender Science Templates

Guangdong faces largest chikungunya outbreak on record | EurekAlert!

An open-access report in the journal Biocontaminant [PDF] describes a sudden, large increase in the number of infections with the chikungunya virus in southern China, with more than 4,000 cases in Foshan City, Guangdong Province, and over 3,600 cases in Shunde District. The initial spread of the outbreak was observed in this region and quickly escalated into a major public health concern. These cases have not only been documented in Guangzhou, Shenzhen, Yangjiang, and Zhanjiang within Guangdong Province but have also emerged in Macao and Hong Kong.

Let’s pretend for a moment that Intelligent Design Creationism accurately describes reality — that a supernatural entity, indistinguishable from the supposedly omnibenevolent god of the Bible, is continually intervening in living organisms to ensure they conform to a divine plan for the world, particularly for human life.

Let’s also assume that William A. Dembski, Michael J. Behe, and other “CDesign proponentsists” are correct in asserting that the presence of “irreducible complexity” and particularly “complex specified genetic information” is evidence of the work of this putative designer.

How, then, does this announcement about the increase in cases of chikungunya in southern China fit into that worldview?

Chikungunya is a virus transmitted to humans only through the bite of a female Aedes mosquito when she takes a blood meal — in much the same way that Zika, yellow fever, and malaria are transmitted. Once infected, a person develops a sudden-onset fever with painful joints and acts as a reservoir for the virus, enabling the next mosquito to pick it up and continue the chain of infection.

The recent increase in cases is believed to be due to two main factors:

• More viruses circulating in the population
• More Aedes mosquitoes, with a northward spread driven by global warming

The genetic information in the chikungunya virus genome is clearly enabling the virus population to increase in response to environmental change. If this doesn’t qualify as “complex specified information”, it’s difficult to imagine what would.

Furthermore, the feeding strategy of the Aedes mosquito is a striking example of a finely tuned process: if any part of it fails, the entire transmission cycle collapses. By Michael J. Behe’s own definition, this appears to meet the criteria for “irreducible complexity” and, within that framework, would be touted as conclusive evidence of “intelligent design”.

The inescapable conclusion, then — if we accept the Intelligent Design worldview, in which a divine intelligence is the only possible explanation for such genetic information and irreducibly complex systems — is that both the virus and the mosquito have been intelligently designed to cause human suffering. They seem to have no other purpose than to reproduce themselves and increase infection levels within the population. In other words, according to the logic of ID creationism, this virus was designed with malevolent intent.

Creationism Refuted - Blood suckers Were Around Long Before Creationist Frauds - Leeches are 200 Million Years Older Than We Thought

Macromyzon siluricus Ancient leech, 473 million years old

Rare fossil reveals ancient leeches weren’t bloodsuckers | UCR News | UC Riverside

Artist's reconstruction of the ancient Macromyzon siluricus leech.

EK Chan.

Unlike creationist frauds, leeches haven’t always been blood-sucking parasites. Around 473 million years ago, they were probably marine predators preying on small creatures.

It had previously been assumed that leeches evolved around 150–200 million years ago, but this fossil, found in the Waukesha biota — a geological formation in Wisconsin —might more than double that timeline to 473 million years, if confirmed. This extended timescale makes sense, as the complex adaptations required for a blood-sucking lifestyle would have had longer to evolve. However, the classification is disputed and may be an example of convergent evolution. This fossil shows the large posterior sucker that modern leeches still possess, but lacks the anterior suctorial mouthparts used by leeches today to pierce their victims’ skin and suck blood.

The fossil was discovered by researchers from Ohio State University, but was initially unrecognised for what it was until it was identified by Karma Nanglu, a palaeontologist with the University of California, Riverside, during the early pandemic years. Nanglu collaborated with researchers from the University of Toronto, the University of São Paulo, and Ohio State University on a paper describing the fossil, which is now published in PeerJ.

Malevolent Designer News - How Candida Albicans (Thrush) Is Cleverly Designed to Infect Your Mouth - Evolution Or Malevolent Design?

The yeast fungus Candida albicans (blue) breaks out of human immune cells (red) by forming long thread-like cells called hyphae. The part of the hypha that has already left the immune cells is coloured yellow.

© Erik Böhm, Leibniz-HKI

The dose makes the difference - Leibniz-HKI

As has often been pointed out in these blog posts, the "evidence" offered by Discovery Institute fellows William A. Dembski and Michael J. Behe for an intelligent designer can, by the same logic and using the same evidence, be interpreted as pointing to a theologically awkward malevolent designer. This is a line of reasoning routinely ignored by the "Cdesign proponentcists", who prefer to overlook the many examples of parasites and pathogens—and the evolutionary traits that make them so successful at invading and surviving within their hosts.

A fresh example that creationists will either have to ignore or blame on "The Fall" comes from researchers at the Leibniz Institute for Natural Product Research and Infection Biology. They have shown that the fungus Candida albicans, which causes thrush, has evolved a highly sophisticated and "finely tuned" mechanism for infecting the human mouth while evading the immune system.

The stock creationist response is to shift responsibility onto the biblical myth of "The Fall," retreating into Bible literalism. Yet this is precisely the kind of literalism the Discovery Institute has been at pains to insist is not essential to the notion of intelligent design, which it markets as a scientific alternative to evolutionary theory—or "Darwinism," as they prefer to call it. This rhetorical sleight of hand was central to the Institute’s "Wedge Strategy," devised after the 1987 US Supreme Court ruling in Edwards v. Aguillard, which confirmed that teaching creationism in public schools violated the Establishment Clause of the First Amendment.

The new research reveals that C. albicans produces a toxin called candidalysin in carefully regulated doses that allow it to infiltrate the mucous lining of the mouth. Too little candidalysin, and the fungus would fail to establish itself; too much, and it would trigger an immune response strong enough to destroy it. Normally, C. albicans exists in a round, yeast-like form, but under the "right" conditions it can switch into the filamentous hyphal form typical of fungi. This transformation allows it to penetrate host tissues and, in immune-compromised patients, become life-threatening. It is in this invasive hyphal state that C. albicans produces candidalysin.

The production of hyphae, and therefore candidalysin, is controlled by the gene EED1. By any definition, EED1 would qualify as an example of "complex specified information" according to Dembski’s own formulation — evidence, according to the Discovery Institute, of supernatural intelligent design.

Malevolent Design - How The Poxvirus is 'Intelligently Designed' To Rapidly Multiply

A Survival Kit for Smallpox Viruses - Universität Würzburg

The tRNA ensures the cohesion of the polymerase and the associated factors; without it, they would not arrange themselves in this way.

Image: Clemens Grimm.

Researchers at Julius Maximilian University of Würzburg (JMU) have discovered that poxviruses have developed a unique strategy to multiply rapidly after infecting a host cell. They achieve this by assembling a large protein complex with the help of a transfer RNA (tRNA) molecule. Remarkably, this is the first known example of a ‘chaperone’ function being carried out by a tRNA rather than a protein. Each component of the assembly plays a specific role in the production of new poxviruses. Crucially, the complex only functions when all parts are correctly assembled, and the tRNA is indispensable for this construction.

In other words, the tRNA provides the essential element of the complex, which some might describe—using the Discovery Institute’s own terms—as containing “complex specified information” and forming an “irreducibly complex” system essential to the virus’s success.

By that same logic, it follows that the viruses responsible for smallpox and mpox (monkeypox) must have been intelligently designed. This leaves creationists with an unenviable dilemma:

• Accept the Discovery Institute’s definitions and admit their designer created deadly viruses — theologically awkward.
• Claim another intelligence designs life, beyond their god’s control — even more awkward.
• Abandon the Institute’s “evidence” for intelligent design — politically awkward.

Creationism Refuted - Fossil Record Of Fatal Pathogens In Brazil - 80 Million Years Before Creation Week

Arrows indicated by BL point to the lesion caused by osteomyelitis. HB is the unlesioned part, and MB is the bone marrow.

Tito Aureliano et al. (2025)

Fossils with signs of bone disease were from sauropods, of the same order as Tambatitanis

illustration: Palaeotaku/Wikimedia Commons.

Deadly bone disease wiped out long-necked dinosaurs in what is now the interior of the state of São Paulo, Brazil

According to creationist dogma — though not explicitly stated in the Bible but added later to patch over awkward evidence — death did not enter the world until Eve’s sin somehow allowed it to. Along with death, so the story goes, came parasites, pathogens, and anything else creationists find inconvenient. And, of course, all of this supposedly happened just 6,000–10,000 years ago.

The problems with that are two-fold:

• Firstly, there is the question of what Adam and Eve, and the animals allegedly created for their use, ate. Did the plants they consumed remain alive as they passed through the digestive system, nutrients extracted but the plant cells excreted still living? Or did none of them eat anything at all? Obviously, the myth’s authors didn’t understand that plants are just as alive as animals.
• Secondly, the entire narrative collides with the fossil record, which shows long-dead animals preserved in strata dated to tens or even hundreds of millions of years before the mythical ‘Creation Week’—during the 99.9975% of Earth’s history that creationism simply erases. Those animals had metabolisms dependent on consuming living or dead tissues, and their fossils often show evidence not only of death, but of predation, parasitism, and disease. Many evolved armour plating, spines, and other defences that make sense only in the presence of predators and pathogens.

And here’s a paradox creationists often tie themselves in knots over: did God design humans with an immune system, or was it a post-Fall upgrade? If it was there from the start, then God was already planning for parasites and pathogens—hardly the “perfect” world creationists claim. If it was added later, then God wasn’t omniscient, as he failed to foresee a future need. Either way, the story collapses under its own contradictions.

It is therefore no surprise that researchers from the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) and the Regional University of Cariri (URCA) in Crato, Ceará, Brazil, have found evidence of dinosaurs being infected—and killed—by osteomyelitis around 80 million years before ‘Creation Week’. Fossils of sauropod dinosaurs show clear signs of active osteomyelitis, with no signs of healing, indicating that the disease proved fatal.

Malevolent Design - A Paradox Creationists Pretend Not to See

The ancient city of Jerash, Jordan, epicentre of the Justinian Plague

Progress of the Black Death in Europe

By Flappiefh - Own work from:Natural Earth  Cesana, D.; Benedictow O.J., Bianucci R. (2017). "The origin and early spread of the Black Death in Italy: first evidence of plague victims from 14th-century Liguria (northern Italy)". Anthropological Science 125 (1): 15–24. DOI:10.1537/ase.161011. ISSN: 0918-7960. (page 17),
CC BY-SA 4.0, Link

USF, FAU researchers solve 1,500-year-old mystery: The bacterium behind the first pandemic

The notion of intelligent design — the current flagship of creationism’s attempt to replace scientific realism with magical superstitions and Bible literalism dressed up as “alternative science” — contains a blatant paradox its advocates must ignore: the very same “logic” used to argue that the God of the Bible created living organisms can just as easily be used to argue that any such designer is a malevolent sadist who deliberately increases suffering in the world while ignoring countless ways to reduce it.

The theological problems this raises are never discussed in polite creationist circles, except for the lazy fallback of blaming everything on “The Fall.” But this move exposes intelligent design for what it really is — Bible-literalist religion in disguise. And that sits awkwardly against over half a century of insistence by the Discovery Institute that ID is not a religious idea, but rather a scientific one that should be taught in American public schools at taxpayer expense — a direct violation of the Establishment Clause and the U.S. Supreme Court’s ruling in Edwards v. Aguillard (1987).

The paradox lies in the fact that the very same so-called evidence — Michael J. Behe’s “irreducible complexity” and William A. Dembski’s “complex specified genetic information” — can be found in the genomes, structures, and processes of parasites and pathogens, making them devastatingly effective at exploiting and destroying their hosts. In fact, Behe himself has, probably without realising it, used precisely such examples. The bacterial flagellum he highlights enables E. coli to move efficiently through our gut, causing sometimes fatal food poisoning. And his example of resistance to anti-malarial drugs in Plasmodium parasites illustrate how evolution equips them to continue killing hundreds of thousands of children every year while condemning millions more to cycles of malarial fever.

Now, new research has highlighted another gruesome example. The bacterium Yersinia pestis — responsible for multiple waves of plague throughout the Middle Ages — has been shown to have evolved into its highly lethal form only in relatively recent human history. Beginning with the “Plague of Justinian” about 1,500 years ago, Y. pestis unleashed pandemics that killed between 30% and 50% of Europe’s population.

An interdisciplinary team at the University of South Florida (USF) and Florida Atlantic University (FAU), with collaborators in India and Australia, has now confirmed genomically that the Justinian plague was indeed caused by Y. pestis, as long assumed. Analysing DNA from plague victims buried in a mass grave at the ancient city of Jerash, Jordan — the epicentre of that pandemic — one group identified the culprit, while another team traced the bacterium’s evolutionary changes that made it one of history’s most notorious killers.

Malevolent Designer - How Creationism's Divine Malevolence Is Actively Killing Children With Malaria - If You Belive ID Creationists

Novel Maneuver Helps Malaria Parasite Dodge the Immune System | Newsroom | Weill Cornell Medicine

Here’s one of those discoveries in biological science that should have ID creationists jumping up and down yelling, "Told you so!". It’s news that the parasite that causes malaria shows both what they call 'irreducible complexity' and 'complex specified genetic information'. According to Discovery Institute fellows Michael J. Behe and William A. Dembski, that would mean it is intelligently designed and, by implication, designed to do exactly what it does — by the Christian God.

But, for reasons which can only be guessed at — and probably not a million miles from the fact that this conclusion would mean the Christian god is actively designing ways to kill people, particularly children, and especially in Africa — creationists tend to ignore it. After all, that’s the very antithesis of the compassionate, benevolent, loving god of the Bible.

Instead, they quietly sidestep the inconvenient reality that examples of their supposed 'proof of intelligent design' are found just as often in parasites and pathogens as in their hosts. This is precisely what evolutionary biology predicts: a host–parasite relationship invariably leads to an evolutionary arms race, producing sophisticated and complex systems that equip the parasite to survive in the host and to infect new victims.

And, true to form, we now have another such example in the major cause of malaria, Plasmodium falciparum, which killed some 569,000 people in Africa in 2023:

Key Facts:

• Globally in 2023, there were an estimated 263 million malaria cases and 597,000 malaria deaths in 83 countries.
• The WHO African Region carries a disproportionately high share of the global malaria burden.
• In 2023, the WHO African Region was home to 94% of malaria cases (246 million) and 95% (569,000) of malaria deaths (432,400 children under 5).
• Children under 5 accounted for about 76% of all malaria deaths in the Region.

Malevolent Design - How 'Intelligent Design' Exposes Divine Malevolence

Schistosoma mansoni

Schistosoma mansoni

Parasitic Worms Evolved to Suppress Neurons in Skin - AAI News

It gets tedious repeating this point so often, but so long as creationists keep using what they claim is irreducible complexity and/or complex specified genetic information as evidence for intelligent design, they need to be reminded that the same argument can also be used as evidence of their putative designer’s malevolence.

Creationists, of course, ignore the fact that parasites are no less “designed” than humans and have structures and processes that are “irreducibly complex” and depend on “complex specified information” in order to succeed in their environments. Yet their existence, and how they interact with and even manipulate their hosts, inevitably increases suffering in the world – a theological problem that creationist disinformation organisations such as the Discovery Institute avoid like the plague.

Parasite–host relationships also inevitably involve evolutionary arms races – the antithesis of intelligence if both “sides” are supposedly designed by the same designer.

So, to keep reminding them: if their justification for designating their god as the designer of living systems holds true, then it is also justification for designating the same god as the cause of suffering. Here is another example of a parasite that falls within their definition of an organism “designed” to do what it does and to participate in an arms race with its host in order to do so. This concerns the discovery that the parasitic worm Schistosoma mansoni, which causes schistosomiasis, is able to suppress neurons in the skin to evade detection as it burrows into its victim’s body (usually the leg).

Malevolent Design - Has Creationism's Intellgent Designer Favoured a Goulish Parasite?

The jewel wasp, Nasonia vitripennis

Nasonia vitripennis female drilling into a host pupa (Calliphora vomitoria)

Wasps may hold the secret to slowing down the ageing process | News | University of Leicester

The jewel wasp, Nasonia vitripennis, is as striking as its name suggests — a tiny, glittering insect that, at first glance, might seem like a textbook example for creationists eager to claim “intelligent design.” Their reasoning, as usual, rests on little more than ignorant incredulity, a lack of understanding of evolution over deep time, and a confusion between the appearance of design and actual evidence for it.

But that enthusiasm evaporates when the facts crawl out. This insect’s life cycle is anything but beautiful — in fact, it’s the sort of thing that would make an all-loving creator god look more like a sadistic tinkerer. The jewel wasp is a parasitoid, laying its eggs inside the pupae of parasitic carrion flies such as blowflies. When the eggs hatch, the larvae devour the pupa from within, eventually emerging as adults, leaving behind only an empty shell.

It takes a particularly selective creationist to ignore this grisly reality and still point to the wasp’s jewel-like beauty as proof of divine craftsmanship, viewed through the narrow lens of human aesthetic tastes.

Now, researchers at the University of Leicester have discovered that — if creationist claims were taken seriously — these wasps have been uniquely blessed with the power to suspend ageing during their parasitic phase, a privilege denied to other organisms.

Refuting Creationism - Ancient Viruses Hidden in Bird Genomes Reveal Evolution in Action

Phylogenomics Unveils the Complex Evolution of Retroviruses in Birds | Molecular Biology and Evolution | Oxford Academic

Information about endogenous retroviruses is normally unwelcome news for creationists because they form phylogenies which exactly map onto the evolution of different species from common ancestry. This is no less true of a new research paper published by four researchers from the College of Life Sciences, Nanjing Normal University, Nanjing, Jiangsu, China, published in Molecular Biology & Evolution.

Endogenous retroviruses for part of the 'junk' (non-coding/non-regulatory) DNA, but some of it have been exapted for other functions over the years and some of it has placed an evolving taxon onto a new evolutionary trajectory. For example, one exapted retrovirus with immuno-suppressive qualities has made placental mammals possible without the growing embryo being treated as a parasite and attacked by the mother's immune system.

The researchers have uncovered the complex evolutionary history of retroviruses in birds by analysing their genetic “fossils” — endogenous retroviruses (ERVs) — embedded in bird genomes. They scanned the genomes of 758 bird species and identified more than 470,000 ERV sequences, revealing a vast and previously underestimated diversity of retroviruses. These sequences are the remnants of ancient viral infections that became part of the host DNA, passed down from generation to generation.

Creationism Refuted - Complex Specified Information in 'Spanish Flu' Virus Makes ID Creationists Sick

Emergency hospital in Zurich’s Tonhalle during the so-called “Spanish flu” in November 1918

Image: Schweizerisches Nationalmuseum, Inventarnummer LM-102737.46

Swiss Genome of the 1918 Influenza Virus Reconstructed | UZH

A major stumbling block that non-biologist Christian fundamentalist theologian William A. Dembski has blundered into is that his so-called ‘proof of intelligent design’ (i.e., the Christian god) also, by the same reasoning, constitutes evidence for malevolent design — something found in virtually every genome of every parasite and pathogen. This presents CDesign proponentsists with a fatal paradox: either their ‘proof of intelligent design’ also proves the existence of an evil designer, or ‘complex specified information’ is not the definitive evidence for design they like to claim it is.

A classic example — and another blow to creationist reasoning—has just been described in a study by researchers from the Swiss universities of Basel and Zurich. They have recovered and analysed the genome of the virus responsible for the 1918–1920 ‘Spanish flu’ pandemic, which killed more people than were killed in the First World War. In fact, the term ‘Spanish flu’ is a misnomer; the virus is now believed to have originated in a U.S. military base in Kansas and was brought to Europe by American soldiers.

The Swiss team discovered that from the outset, the virus appears to have been pre-adapted for infectivity and immune evasion. They identified three key mutations that remained unchanged as the virus evolved over the course of the pandemic. Two of these mutations made the virus resistant to an antiviral component of the human immune system, while the third enabled it to bind more effectively to receptors on the surface of human cells, allowing it to enter and infect them more readily. These mutations were so effective that victims frequently died within hours of the onset of symptoms.