Monday, 6 February 2023

How Science Works - Changing Minds When the Evidence Changes

How Science Works

Changing Minds When the Evidence Changes
Auditorium Cave near Bhopal, India
Credit: Joe Meert

Mistaken fossil rewrites history of Indian subcontinent for second time - News - University of Florida

It's a source of embarrassment to the scientists concerned, and no doubt a small crumb of comfort to those anti-science extremist propagandists trying to fool scientifically illiterate simpletons into thinking science is unreliable, that scientists have discovered a major mistake.

To those who understand science and how scientific opinion is always contingent and subject to revision and where nothing is ever cast in tablets of stone; where the only certainty is that there are no certainties, it is always rewarding and reassuring when mistakes are discovered and corrected because this shows the scientific method is working.

Just such an example came to light recently when scientists revisited the site where a fossil, thought at the time it was first discovered to be highly significant, had been found. What they discovered was that the ‘’ not only was nothing of the sort, but was actually in an advanced state of decay and peeling off the wall of the cave in which it had been found about a year earlier - things no self-respecting fossil should be doing.

It turned out that the 'fossil' was the recent remains of a wild honeybee (Apis dorsata) hive which, when discovered, bore a remarkable resemblance to an Ediacaran fossil, Dickinsonia tenuis, only previously known from South Australia. The implications for the age of the rock formation in which it was appeared to solve the problem of accurate dating of the rock formation and its origins in the ancient supercontinent, Gondwanaland, some 550 million years ago.

Sunday, 5 February 2023

Secular News - UK Now a Majority Non-Christian Country

Secular News

UK Now a Majority Non-Christian Country

Religion, England and Wales - Office for National Statistics

For the first time in a census of England and Wales, less than half of the population (46.2%, 27.5 million people) described themselves as “Christian”, a 13.1 percentage point decrease from 59.3% (33.3 million) in 2011; despite this decrease, “Christian” remained the most common response to the religion question.

Pie chart of major religions UK 2021
The main England & Wales religious demographics
Source: ONS
Figures released recently by the UK Office of National Statistics (ONS) show that in the 2021 census, in answer to a voluntary question, less than half (46.2%) of the 56.0 million people who answered (94%) self-identified as 'Christian'. This represents a 13.1 percentage point decrease from the figure for 2011 for the same voluntary question.

The second most common answer was 'no religion', up by 12 percentage points from 25.2% (2011) to 37.2%.

Religious Abuse - How Religion Deprives Children of Their Human Rights in Northern Ireland

Religious Abuse

How Religion Deprives Children of Their Human Rights
in Northern Ireland

Political map of Northern Ireland
Political divide in Northern Ireland
Reports: Rights of children in NI undermined by religion - National Secular Society

Reports recently submitted to the United Nations Committee on the Rights of the Child (UNCRC) by the Northern Ireland based child rights advocacy group, The Children's Law Center (CLC) demonstrate how religion continues to poisoning community relations, maintain divisions and hostility and deprive people of basic human rights, in Northern Ireland.

Despite years of progress following the end of the 'troubles' with the 'Good Friday' Belfast Agreement and the establishment of a power-sharing executive to administer devolved political power, the major source of intercommunal tension continues to be religion. The single most important barrier to the removal of religion as a source of hostility is the de facto segregation of primary and secondary education because of the insistence by the main Christian churches that they are not only influential in, but have control of education.

Despite a poll in 2012 which showed that 71% of the people of Northern Ireland believe an integrated education system should be the "primary model for the education system" and a 2016 UNCRC recommendation that Northern Ireland "actively promote a fully integrated education system" to facilitate "social integration, 93% of children in the province still attend faith schools while the few fully integrated schools can't meet the demand. In effect, parents have no choice but to send their children to be indoctrinated into one or other of two mutually hostile camps.


In 2016, the UNCRC also recommended ending the legally mandated collective worship in Northern Ireland schools where, unlike in England and Wales, even children over the age of 16 have no right to withdraw themselves from collective worship. Last year the High Court in Northern Ireland agreed that this situation is incompatible with the European Convention on Human Rights. Although parents can withdraw their children from collective worship, the process is often difficult, and children rarely receive an alternative period of equal educational value. Children are also required to reveal details of their beliefs, in violation of their right to privacy, and often face stigmatisation and prejudice.

As part of their religious education syllabus, faith schools are permitted to include their religion's orthodox teaching on relationships and sex education, leaving LGBTQ+ students feeling that they are the victims of homophobic bullying and demonisation, again in violation of their basic human rights.

There is no requirement for Northern Ireland's schools to teach evolution in science class and, unlike in England, where state-funded schools are forbidden from teaching scientifically discredited superstitions like creationism and intelligent design as science, no such bar exists in Northern Ireland where creationism in its various forms can be presented to children as a valid alternative to the scientific view, and the Christian Bible can be taught as real science and history.

Indeed, the state is complicit in misleading children and depriving them of a sound, evidence-based education, or an objective view of religions, because schools are required to teach RE "based on the holy scriptures", with the syllabus designed by the "four main Christian churches", without non-religious, or non-Christian input. Religions besides Christianity are described as "other religions", illustrating Christianity's privileged position. There is no provision to objectively evaluate the claims of the various religions or make an meaningful comparison between them and the non-religious view of the world.

Despite the diminishing role and influence of religion in both the Republic of Ireland and the United Kingdom, religion continues to hold sway in Northern Ireland, and in doing so, continues to foment and encourage intercommunal tension and strife while pretending to be peacemakers. Clearly, the interests of the priests and the churches is paramount and the interests of the people comes way down the list of priorities.

Wednesday, 1 February 2023

Creationism in Crisis - Leading Scientist Still Reject God

Creationism in Crisis

Leading Scientists Still Reject God
"Adam and Eve,” detail, by Giulio Clovio, 1546
from the Book of Hours of Cardinal Alessandro Farnese.
Pierpont Morgan Library,
New York City, USA


Leading scientists still reject God | Nature

I'm grateful to David Edwards whose comment on my blog post, Creationism in Crisis - How the Bible Narrative Misled 19th Century Palaeontologists drew my attention to this correspondence published in Nature a few years ago.

It is yet more bad news for those few dupes who still believe the absurd Creationist lie that the Theory of Evolution is a theory in crisis and about to be replaced by their childish superstition complete with magic and unproven supernatural entities.

In their correspondence, the authors, Edward J. Larson, of the Department of History, University of Georgia, Athens, Georgia, USA and Larry Witham of Burtonsville, Maryland, USA, report on the findings of a survey which shows that disbelief [in a god] is almost total amongst "top natural scientists".

The authors repeated the survey conducted in 1914 by the eminent psychiatrist, James H. Leuba, in which he found that 58% of 1000 randomly selected scientist expressed doubt or disbelief in the existence of God and that this figure rose to near 70% among the 400 "greater" scientists in his sample.

On repeating his survey 20 years later in 1933 (published in 1934), Leuba found that these percentages had risen to 67 and 85, respectively. He attributed this higher level of disbelief in the "greater" scientists to their "superior knowledge, understanding, and experience". This view was echoed by Peter Atkins of Oxford University in his comment on Larson's and Witham's 1996 paper, in which he said, "“You clearly can be a scientist and have religious beliefs. But I don't think you can be a real scientist in the deepest sense of the word because they are such alien categories of knowledge.”

It was in response to this and similar comments that Larson & Witham decided to rerun the second phase of Leuba's study to compare the religious beliefs of "greater" and "lesser" scientists. They defined "greater" scientists as those belonging to the US National Academy of Sciences:

Tuesday, 24 January 2023

Creationism in Crisis - How the Bible Narrative Misled 19th Century Palaeontologists

Creationism in Crisis

How the Bible Narrative Misled 19th Century Palaeontologists

Reconstruction of the ceremonial burial
Credit: Natalia Klimczak
© National Museum of Wales

Paviland Cave, Gower, South Wales
Paviland Cave (Goat’s Hole), Gower Peninsula
Red Lady of Paviland: the story of a 33,000 year-old-skeleton – and the calls for it to return to Wales

The significance of the discovery of human remains in a Welsh cave almost exactly 200 years ago to the day, on 18 January, 1823, was entirely missed because the Oxford University Palaeontologist, William Buckland, was also an Anglican priest who believed the Bible to be the inerrant word of a creator god and so literal history.

Today, this is something only believed by scientifically illiterate Creationists and those made too afraid by childhood indoctrination to question it or acknowledge the evidence to the contrary.

After changing his mind several times, Buckland concluded on scant evidence that the skeletal remains were that of a female prostitute who had drowned in the Biblical flood and whose body had got washed into the cave along with the other animal remains found there, because this was the only way he could think of to fit the facts into the Bible narrative.

In fact, the body is that of a man of about 25-28, who died about 33,000 years ago and so is the earliest example of a ceremonial burial in Western Europe. In taking the remains, together with the artifacts found with them, back to Oxford and failing to recognise their cultural significance to Wales, he so deprived Wales of a cultural icon.

The story of how the Bible, or rather the mistaken belief that the Bible is literal history, mislead 19th Century palaeontologists is told by Ffion Reynolds, Honorary Research Fellow, and Jacqui Mulville, Professor in Bioarchaeology and Head of Archaeology and Conservation, both of Cardiff University, in an article in The Conversation. The article is reprinted here under a Creative Commons license, reformatted for stylistic consistency.

Monday, 23 January 2023

Creationism in Crisis - Humans Carry Traces of Ancestral Species

Creationism in Crisis

Humans Carry Traces of Ancestral Species
A reconstruction of the permian synapsid
Dimetrodon grandis

Branchiostoma lanceolatum
Branchiostoma lanceolatum

We can still see these 5 traces of ancestor species in all human bodies today

Your genes haven't always been human. In fact most of them have spent far more time not being human than they have being human.

This is because you inherited them from your parents and their parents before them, going right back to before your ancestors were human; before they were mammals, before they were vertebrates, and even before they were multicellular organisms.

To quote from my book, What Makes You So Special? From the Big Bang To You:
You are the product of billions of passes through the sieve of selection and at every pass your gene-line passed the fitness test. Your genes are good at surviving; and you are unique in the history of the cosmos. The likelihood of you being alive at all is almost vanishingly small and yet here you are. Never before has anyone with your combination of genes, your collection of atoms and your history existed.

And you never will again.

Almost all your genes have spent much longer being something else than they have being human. Your ancestors were there when Europe and Africa split off from the Americas. They were there as small mammal-like reptiles when dinosaurs ruled the earth. They saw pterodactyls flying overhead. They survived the mass-extinction which ended the dinosaurs’ reign and they saw the birds and the bats grow wings and take to the air.

Your ancestors swam in the Cambrian seas and crawled out onto the land as early air-gulping fish destined to become four–legged animals with lungs. Your ancestors lived through the Carboniferous era when dense forests of tree ferns grew in steaming jungles where dragonflies with meter-wide wings flew. They saw the trees fall and form the piles of vegetation destined to be coal as the climate changed and the Carboniferous forests collapsed. They saw the first flowering plants as plants and insects formed their mutual-benefit society.

Your ancestors lived through the first great toxic waste disaster when the cyanobacteria produced oxygen and triggered a mass extinction; and they learned to turn it to their advantage by evolving aerobic respiration.

Your ancestors were bacteria; maybe they were archaea; they may have been the strange Ediacarans which were the earliest known multi-cellular organisms. In almost every one of your cells, in your genes, you carry a record of your evolution, of the entire human evolution story, and of a great deal of the evolution story of every other living thing.

Your journey through space and time has been an adventure of disasters, adaptation, survival and recovery, many, many times you will have been on the brink of extinction - the fate of 99% of all known ancient species - yet your ancestors survived and because they were good at surviving you are here and now.
In the following article, reprinted from The Conversation under a Creative Commons licence, Alice Clement, Research Associate in the College of Science and Engineering, Flinders University, Australia, identifies five key features we have inherited from remote ancestors. These are:
  1. Bipedal walking, including changes to our pelvis - inherited from archaic hominins.
  2. Openings in our skull, inherited from our synapsid ancestors, which includes relatives of the Dimetrodon.
  3. Five fingers and toes, inherited from our fish ancestors that first emerged onto land.
  4. Teeth, inherited from early jawed fish from the Silurian, about 14 million years ago.
  5. The spinal chord and vetebrae, inherited from early chordates which evolved a 'notocord', some 500 million years ago.
The original article has been reformatted for stylistic consistency.

Sunday, 22 January 2023

Malevolent Designer News - How Creationism's Divine Malevolence Capriciously Choses Random Victims

Malevolent Designer News

How Creationism's Divine Malevolence Capriciously choses Random Victims

Study reveals new genetic disorder that causes susceptibility to opportunistic infections | VUMC Reporter | Vanderbilt University

Creationists are obliged by the dogma of their cult to believe that nothing in genetics happens by chance, so everything about an individual’s genetic makeup is the deliberate creation of their putative designer. Indeed, this creator choses the exact sperm that will fertilise the ovum to produce the intended individual complete with the precise genetic makeup of that individual, including any mutations that arise in the creation of the sperm and ovum.

So it must come as something of a shock to creationists to discover that their putative creator appear to randomly create individuals with genes that predispose them to genetic defects and illnesses that mean they will inevitably suffer through no fault of their own, and apparently regardless of how they have lived their lives. In fact, since these are inherited at conception, the predisposition must be at the capricious will of the creator of it.

One such genetic condition was recently discovered by an international team of researchers co-led by immunogeneticist Rubén Martínez-Barricarte from Vanderbilt University Medical Center who have discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.
The consortium's finding is reported, open access, in Science Immunology.

According to a news release by Bill Snyder of Vanderbilt University:

Evolution News - Neanderthals In France Unaffected by Climate Change

Evolution News

Neanderthals In France Unaffected by Climate Change
Artist's representation of Neanderthals hunting a mammouth

Spear in hand

Credit: Matteo De Stefano/MUSE, CC BY-SA
In the Neanderthal site of Combe-Grenal, France, hunting strategies were unaffected by changing climate: Hunted animals at Combe-Grenal consistently came from open tundra-like habitats -- ScienceDaily

In a very neat example of how much information can be obtained by forensic examination and deductive logic, a team of paleoarchaeologists have shown that because climate change, profound though it was at times, never changed the food or distribution of the animals they hunted, Neanderthals in France never needed to change their hunting strategies.

This conclusion was arrived at after examining the microwear on the surface of the teeth of the remains of hunted animals found at the Combe-Grenal site in France. This microwear showed that, during the few weeks before they were killed, they ate the same vegetation regardless of the climate on the European tundra as the climate fluctuated widely during the Middle Palaeolithic from around 150,000 to 45,000 years ago when Neanderthals intermittently occupied the site.

The scientists' findings are published open access in PLoS ONE.

According to information supplied by PLOS:

Biodiversity News - In The Chinese Year of the Rabbit, Several Related Species are Endangered

Biodiversity News

In The Chinese Year of the Rabbit, Several Related Species are Endangered
European brown hare, Lepus europaeus

European hare,
In the Year of the Rabbit, spare a thought for all these wonderful endangered bunny species

The once common European brown hare, Lepus europeaeus has declined by 80% in the UK in recent years, and, as the Chinese year of the Rabbit is about to begin, it's not the only threatened species of the order Lagomorpha, to which rabbits, hares and other related species belong.

In the following article, reprinted from The Conversation under a Creative Commons license, Emma Sherratt, Senior Research Fellow in Ecology & Evolutionary Biology, University of Adelaide, Australia, list just a few of the 108 lagomorphs, two-thirds of which were already threatened by climate change. Now the number endangered has risen from 13 to 16.

Her original article has been reformatted for stylistic consistency.

Friday, 20 January 2023

Evolution in Crisis - Wild Animals Are Evolving Faster Than Anybody Thought

Creationism in Crisis

Wild Animals Are Evolving Faster Than Anybody Thought
Eurasian blue tit, Cyanistes caeruleus

Great tit, Parus major
Great tit, Parus major, one of the species studied

Wild animals are evolving faster than anybody thought

In a paper published in Science last May, a team of research biologists led by Timothée Bonnet of the Australian National University presented evidence that should create consternation and anguish amongst Creationist frauds intent on convincing their cult members that the Theory of Evolution is somehow in crisis and being increasingly rejected by research biologists in favour of their childish origin myth. It reports the finding that evolution is proceeding even faster than anyone previously thought.

Of course, the definition they used for evolution is the standard scientific one of change in allele frequency over time, not the absurd Creationist notion that it means one species suddenly changing into another, or even organisms changing into humans via a few 'intermediate species'.

One of the studies, on great tits, was carried out just a stones throw from where I live, in Wytham Wood, near Oxford, one of the most intensively studied areas of woodland in the world, belonging as it does to Oxford University. The research and its significance were reported in an article in The Conversation written by lead author, Timothée Bonnet, researcher in evolutionary biology (DECRA fellow), Australian National University. The article is reprinted here under a Creative Commons licence. It is reformatted for stylistic consistency.

Creationism in Crisis - Watching Evolution Down Under

Creationism in Crisis
Watching Evolution Down Under

Could feral animals in Australia become distinct species? It's possible – and we're seeing some early signs

Australian feral domestic cat
Australian feral domestic cats are getting bigger
Evolution is defined as change in allele frequency in a population over time. It is not a single event but a slow process which often needs a long period of time to be observed. Speciation may be the incidental result of this process of change over time but it is not the purpose of it, nor is it required for evolution to be occurring.

It doesn't seem to matter to a Creationist that observable examples of evolution in progress, in other words, examples of observed change in allele frequency in the population over time, can be found throughout nature, because they will simply dismiss it by redefining evolution as the childish notion of a sudden change of one species into another. So, for example, evolutionary changes in Australian feral domestic cats will be dismissed as, "But they're still cats!"

In fact, feral domestic cats are not the only species that can be observed evolving in Australia where a combination of the founder effect, genetic drift and natural selection in the unique Australian environment are causing introduced species to diverge from their ancestral species. In the following article, Bill Bateman, Associate professor, Curtin University, Perth, Western Australia, describes a number of examples of observable evolutionary change.

Creationists who have been fooled into believing that evolution is a theory in crisis and biologists are abandoning it in favour of their childish superstition including magic and a supernatural entity should note the complete lack of any evidence for that idiotic notion. The article describes evolutionary changes and the causes of them which are entirely consistent with the scientific Theory of Evolution. No-where are magic or supernatural entities invoked to explain the observations.

The article is reprinted from The Conversation under a Creative Commons license, reformatted for stylistic consistency.

Monday, 16 January 2023

Creationism in Crisis - How Humans Evolved to Live in Cold Climates

Creationism in Crisis

How Humans Evolved to Live in Cold Climates
Most humans haven't evolved to cope with the cold, yet we dominate northern climates – here's why

Turku, Finland in Winter
Turku, Finland in Winter

Jarmo Piironem/Eyem/Getty Images
With the exception of only a few, relatively minor, changes to our genome, such as loss of skin pigmentation and changes to hair and eye colour, and the ingression of Neanderthal and Denisovan genes, non-African humans differ little from the first Homo sapiens to venture out of Africa, where they had evolved as a tropical species. Today, humans are the only Great Ape to live outside of the tropics.

And yet we have managed to live in northern climates with shorter days in winter and sub-zero temperatures in which the earliest members of our species would probably not survive a night without special measures.

With our physical and physiological makeup differing so little from our African forebears, what has enabled us to survive in these hostile conditions to which we were so mal adapted? The answer is that an additional layer of evolution is operating alongside genetic evolution - memetic, or cultural, evolution - so-called gene-meme co-evolution.

Memetic evolution has taken us from the bands of hunter-gatherers huddled round a campfire and sheltering in caves and rock overhangs, to a modern urbanised, hi-tec species living in centrally heated buildings or dressing in warm clothing and entirely dependent on science and technology for our survival. Put us naked out in the open on a cold winter night and few of us would survive, let alone thrive, and survival without cloths and shelter would be impossible on the arctic tundra even in summer.

In the following article, reprinted from The Conversation, Laura Buck, Lecturer in Evolutionary Anthropology, and Kyoko Yamaguchi, Senior Lecturer in Human Genetics, both of Liverpool John Moores University, explain how we and our cousin species, the Neanderthals adapted to the very non-African conditions they found themselves in.

The article has been reformatted for stylistic consistency; the original can be read here.

Sunday, 15 January 2023

Creationism in Crisis - How Our Immune Systems Have Evolved Over the Last 10,000 Years

Creationism in Crisis

How Our Immune Systems Have Evolved Over the Last 10,000 Years
Using paleogenomics to elucidate 10,000 years of immune system evolution | Institut Pasteur
Explanatory diagram
Explanatory diagram.
© Gaspard Kerner, Institut Pasteur
By analysing the genomes of more than 2,800 individuals who lived in Europe over the last 10,000 years, scientists at the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France, in collaboration with the Imagine Institute and The Rockefeller University, USA, have traced how the European human immune system has evolved over that period. The increase in frequency of most of the mutations that are advantageous in defending against pathogens were dated to after the Bronze Age, 4,500 years ago.

The scientists also observed that most of the mutations conferring a higher risk of developing inflammatory disorders have become more frequent over the past 10,000 years, suggesting that there is an evolutionary trade-off between greater immunity and greater risk of auto-immune, inflammatory disorders.

This trade-off, is, of course, something that we would not expect to see if the immune system had been improved by an intelligent designer, unless the designer malevolently intended us to suffer from auto-immune conditions.

The evolutionary explanation for this is simply that most of the benefit of a strong immune system manifests in childhood and early adulthood, before the individual has been exposed to environmental pathogens and built up a library of antibodies, and before they have had chance to produce offspring, when selection pressures are thus higher, whereas most of the detriment of auto-immune inflammatory conditions tends to occur in later life, after the individual has reproduced, when the selection pressure is thus much lower.

The research has just been published open access in the journal Cell Genomics.

The research and its significance are explained in a news release from the Institut Pasteur:

Creationism in Crisis - Perto Rican Lizards Evolving

Urban Lizards Share Genomic Markers Not Found in Forest-Dwellers
Puerto Rican crested anole, Anolis cristatellus
Puerto Rican crested anole, Anolis cristatellus
Photo credit: Kristin Winchell
Unlike creationism which, because it depends on magic and unproven, unfalsifiable magic supernatural entities, is incapable of making falsifiable predictions, the Theory of Evolution by Natural Selection (TOE) predicts that, from the same starting point, the same environmental changes will produce the same or very similar phenotypic changes, such as that recently reported for populations of lizards in Puerto Rico.

A paper recently published in Proceedings of the National Academy of Science (PNAS), reports on a case of parallel evolution between populations of the Puerto Rican crested anole, Anolis cristatellus, where unconnected populations in urban areas have evolved very similar adaptations to an urban environment compared to those living in a forest environment. The paper reports the findings of a team of researchers led by assistant professor of biology, Kristin Winchell, of New York University (NYU), NY, USA.

The NYU news release explains the research and its significance:

Saturday, 14 January 2023

Trumpanzee News - What Causes People to Fall For Conspiracy Theories?

Bullying, power and control: why people believe in conspiracy theories and how to respond
QAnon conspiracists in the failed insurrection
A supporter of President Donald Trump, seen wearing a QAnon shirt, is confronted by Capitol Police officers outside the Senate Chamber during the invasion of the U.S. Capitol
Credit: AP Photo/Manuel Balce Ceneta
It's probably hard for rationl people to understand why some people fall for such ludicrous conspiracy theories as the QAnon hoax that Donald Trump was fighting the Satanic cannibalistic paedophile ring led by Hillary Clinton and Barak Obama that is secretly running the 'deep state', or that the 2020 election was stolen (apparently without leaving a trace of evidence that would stand up in court). The same fruit loops have also been convinced that the odious liar, crook, serial adulterer, and incompetent narcissist, Trump was send by God to fight Satan and that God had told various self-appointed 'prophets' that Trump would win by a landslide in 2020, so he must have done really.

As it became more and more apparent just how badly Trump lost, being the only presidential candidate in American political history to lose the popular vote twice and that Joe Biden had won it by a record margin, so the conspiracy theories became more and more lurid.

So why do some credulous fools fall for these unlikely theories, usually involving vast secret conspiracies such as the entire scientific community together with all their technical and administrative staff and everyone involved in publishing scientific books, periodicals and papers, or senior military leaders and heads of government of even hostile states, together with their advisors and civil service?

In the following article, reprinted from The Conversation under a Creative Commons license, Daniel Jolley, Assistant Professor in Social Psychology, University of Nottingham, UK and Anthony, Lantian, Associate Professor in Psychology, Université Paris Nanterre – Université Paris Lumières, France, explain the psychology and the social causes of this gullibility and readiness to believe the patently absurd. The article, the original of which can be read here, is reformatted for stylistic consistence.

Malevolent Designer News - Creationism's Divine Malevolence is Getting Better At Killing People

The 'kraken' COVID variant XBB.1.5 is rising quickly in the US – here's what it could mean for the UK
Credit: peterschreiber.media/Shutterstock

As is entirely predictable from the Theory of Evolution, the SARS-CoV-2 virus that has caused the ongoing COVID-19 pandemic, has mutated to produce an even more infectious version - a subvariant of the Omicron variant, given the variant name XBB.1.5 and nicknames 'kraken', under the suggested new protocol of naming significant variants after Greek mythological creatures instead of letters of the Greek alphabet..

This appears to have originated in the USA where a large number of people have resisted getting vaccinated due to the politically-motivated antivaxx campaign by the far right supporters of failed president, Donald Trump,. Trump declared the pandemic to be a hoax and COVID-19 to be a mild illness, early on in the pandemic, when he was out of his depth and panicking over how to cope with the emergency. Having acted out of spite and motivated by racism and a desire to expunge his achievements, Trump had stupidly dismantled the contingencies for just such a pandemic put in place by his hated African-American predecessor, Barak Obama.

Inhibited from doing so by his narcissistic personality disorder, Trump was then unable to admit he got it wrong and his cronies in the Repugnican Party and the evangelical white Christian sects set about campaigning against any measures to mitigate the effects of the pandemic, including establishing the QAnon cult to promulgate disinformation.

The upshot is a high degree of vaccine scepticism in the USA with a significant majority being vaccinated - a recipe for producing lots of new variants in the unvaccinated population which will then find a niche in the vaccinated population, if they can evade the antibodies.

But is this variant anything to be overly concerned about?

In the following article, reprinted from The Conversation under a Creative Commons licence, Dr. Grace C Roberts, a research fellow in virology at the University of Leeds, assesses the risks from this new variant for the world in general and the UK in particular. The article has been reformatted for stylistic consistency. The original can be read here.

The ‘kraken’ COVID variant XBB.1.5 is rising quickly in the US – here’s what it could mean for the UK


Grace C Roberts, University of Leeds

The heavily mutated omicron variant of SARS-CoV-2, the virus that causes COVID-19, was first detected in late 2021.

Due to the many mutations in the spike protein (a protein on the surface of SARS-CoV-2 that allows the virus to attach to our cells) omicron was able to quickly become the dominant SARS-CoV-2 variant. These mutations allowed it to bind to respiratory cells more tightly than previous variants, rendering it more infectious.

Owing to the dominance of omicron, thanks to these mutations, the past several months have seen the emergence of many subvariants of omicron (scientists have identified more than 650 to date).

The latest variant to worry health professionals and virologists alike is XBB.1.5, nicknamed “kraken” by a group of scientists that has been naming new variants after mythological creatures to make the virus’ evolution more accessible to the public. Here’s what we know about it.

XBB.1.5 is a derivative of the XBB variant of omicron. XBB was never designated as a variant of concern by the World Health Organization because data shows that, while XBB’s mutations enable it to evade our immune systems better than previous omicron subvariants, it doesn’t appear to be causing an increase in infection rates.

In addition to the mutations that XBB.1 has, XBB.1.5 also carries a mutation called S486P in the spike protein region. Preliminary laboratory studies, yet to be peer-reviewed, have shown that, similar to XBB.1, XBB.1.5 is less sensitive to antibodies acquired from vaccination than previous variants XBB and BQ1.1. So it’s very good at evading our immune response.

The same preprint showed that XBB.1.5 was able to bind to ACE2 (the receptor the virus uses to infect our cells) more strongly than these earlier variants. This is the characteristic that made the original omicron variant so infectious and so dominant.
Having first been detected in October 2022 in the US, XBB.1.5 has spread rapidly in the country and is now responsible for around 28% of all new infections. Elsewhere, XBB.1.5 has been detected in at least 23 countries, including the UK. But according to the most recent data, it accounts for only 4% of COVID infections in England.

Given what we’re seeing in the US, it’s likely that XBB.1.5 will become the dominant strain in the UK and Europe in time. But as there are always differences in populations (for example, vaccination rates and social behaviour) it’s hard to predict exactly how things will play out.
A woman at a bus station wearing a mask.
XBB.1.5 is rife in the US, but not in the UK and Europe at this stage.
So should we be worried?

Though some of XBB.1.5’s characteristics are concerning, the real-world infection data is not showing an overall increase in infections or deaths globally or in the US (where XBB.1.5. is rife) at present.

It’s too early to tell whether infections from XBB.1.5 are more severe than previous variants, however experts agree that there is no evidence at this stage that it poses any higher risk than variants that have come before it.

Experts also agree that vaccination will continue to protect against serious disease and death from XBB.1.5.
With a new variant, there’s always the risk it will affect clinically vulnerable people more severely. Older people and those with conditions that affect their immune systems mount weaker responses to COVID vaccines, so are less protected than the “healthy” population. This means variants that spread more easily or can better evade our immune system may be more likely to infect these people if they’re exposed.

So, while COVID continues to circulate, it’s best to take extra precautions when meeting vulnerable people such as wearing a mask, washing your hands thoroughly, ventilating the space that you are in (or even meeting outdoors), and not meeting them at all if you are ill.

The Conversation Grace C Roberts, Research Fellow in Virology, University of Leeds

Published by The Conversation.
Open access. (CC BY 4.0)
It almost goes without saying that for a Creationists to claim intelligent [sic] design at work with these new variants is a tacit admission that their beloved creator god is malevolently designing ways to ensure its virus continues to make people sick and die and to disrupt economies indiscriminately across the world. That Creationists prefer us to have this view of their god rather than accept the science of evolution by mutation and natural selection betrays a hidden political agenda behind Creationism that requites people to distrust science and be misinformed about it.

This is, of course, the stated aim of the Discovery Insitute's failed Wedge Strategy.

Thursday, 12 January 2023

Creationism in Crisis - Improving on the "Intelligent Designer's" Designs

Rice Breeding Breakthrough to Feed Billions | UC Davis
Rice field in Bangall, India
A rice field in Bengal, India. Rice is a staple crop for billions of people, but it has proved difficult to bring high-yield hybrid rice strainers to farmers. UC Davis scientists have developed a method to propagate hybrid rice as cloned seeds, reducing costs for growers and allowing them to save improved seed from season to season.

Getty Images

A paper published a couple of weeks ago should have been a major embarrassment to Creationists who believe the Bible tale that a perfect, supremely intelligent designer designed all the plants and animals of the world for mankind.

If that were the case, why have a team of scientists at UC Davis managed to improve the rice plant - a basic staple in the diet of many people.

In fact, of course, the rice plant, like all human crops and just about every domestic animal, has been improved immeasurably in the few tens of thousands of years since humans transitioned from hunter-gatherers to cattle-herders and farmers.

Epicurus
Epicurus
(341-270 BCE)
Is God willing to prevent evil, but not able? Then he is not omnipotent. Is he able, but not willing? Then he is malevolent. Is he both able and willing? Then whence cometh evil? Is he neither able nor willing? Then why call him God?
If they had been intelligently designed, especially by an omniscient, omnipotent god, they would be perfectly fit for purpose already with no room for improvement. The fact that they aren't, should suggest to Creationists that there is a problem with their notion, since there was self-evidently no omniscient, omnipotent intelligence involved.

Human domestic animals and cultivated crops have been produced by selective breeding, and now genetic engineering, from the wild types that evolved without a plan and fitted only for maximising the number in the next generation. Nothing, and no-one bred wild rice, wild cattle, wild corn or wild sheep for human consumption or ease of harvest and storage. We did that from whatever starting point the natural processes of evolution had provided.

To anyone who understand it, it presents what amounts to the Epicurus Paradox all over again. The research and its significance is explained in an article by Andy Fell in UC Davis News:

Monday, 9 January 2023

Creationism in Crisis - Common Origins of Modern and Neanderthal Humans

Human and Neanderthal brains have a surprising 'youthful' quality in common, new research finds.
Neanderthal man
A picture taken on September 6, 2021, shows the reconstruction of the face of the oldest Neanderthal found in the Netherlands, nicknamed Krijn, on display at the National Museum of Antiquities in Leiden.
Bart Maat/ANP/AFP Via Getty Images
The idea of common origins of related species is a fundamental part of the Theory of Evolution, supported by both countless examples of nested hierarchies and the science of cladistics.

Creationists need to resort to unproven claims of common design, to explain the same or closely similar structures and processes being found in related species. In contrast to the scientific explanation of observable evidence of natural processes with no plan, no intent and no magical mysteries, Creationists need to invoke an unproven, unexplained and unfalsifiable magic supernatural entity, claiming this to be the better of the two for no other reason than that their mummy and daddy believed it and it makes them feel special.

Just such an example of the evidence of common origins has recently been published in Nature Ecology & Evolution which shows that both modern Homo sapiens and Neanderthals had the same rapid evolution of the organisation of the brain that is believed to be responsible for high levels of cognitive ability.

The fact that this is present in two closely related species is highly suggestive that it was present at least in their last common ancestor. It also suggests that Neanderthals had a level of cognitive ability on a par with modern humans.

The research and its significance is the subject of an article in The Conversation by three of the researchers, Professor Stephen Wroe, University of New England, Armidale, NSW, Australia; Dr. Gabriele Sansalone, Institute of Marine Sciences, National Research Council, Messina, Italy, and Professor Pasquale Raia, Department of Earth Sciences, Environment and Resources, Università degli Studi di Napoli Federico II, Monte Sant’Angelo, Naples, Italy. That article is reprinted here under a Creative Commons license, reformatted for stylistic consistency. The original article can be read here.

Saturday, 7 January 2023

Creationism in Crisis - A Double Whammy From Salmonella

New role of small RNAs in Salmonella infections uncovered | Carl R. Woese Institute for Genomic Biology
Pathogenic Salmonella bacteria.
Image Credit: nobeastsofierce / Shutterstock
A paper published last month in the American Society for Microbiology's Journal of Bacteriology would be a double embarrassment for Creationists if they were capable of understanding its implications.

The authors, a research team led by Cari Vanderpool and Sabrina Abdulla of the Carl R. Woese Institute for Genomic Biology (IGB) and the Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA, have shown how the virulence of the pathogenic bacteria, Salmonella, is controlled.

The bad news for Creationists is that:
  • It shows that if this system was designed by an intelligent entity, that entity intended to make people sick, because that's what it does.
  • It involved control of a system known as the type III secretory system, which is related to and very similar to the Type II secretory system that biologists believe was the evolutionary ancestor of the bacterial flagella that Creationist dogma insists was intelligently designed because it couldn't have evolved.
According to News-Medical.net:

Friday, 6 January 2023

Malevolent Designer News - Getting Better At Killing Salamanders With 'Jumping Genes'

A fire salamander.
Credit: Jaime Bosch.
Research news - ‘Jumping genes’ help fungus kill salamanders - University of Exeter

Creationist mode:


Embarrassingly for Creationists, when their divine malevolence wanted to improve the ability of one of its pathogens to kill salamanders, it used a method that Creationists deny exists. It increased the amount of genetic information, not by magic like creationists believe genetic information gets created, but by using one of the methods evolutionary biologists know creates new genetic information naturally, without magic or supernatural entities - so-called 'jumping genes'.

'Jumping genes' or transposons, are pieces of DNA that have the ability to copy and paste themselves into new parts of the DNA, often carrying genes with them. In so doing they add new information into the genome and replicate any genes they carry with them. These copies of genes can them mutate without loss of function because the originals still exist, or as in the case of this fungal pathogen, they can augment the activity (and the virulence) of the original gene.

The fungal pathogen is Batrachochytrium salamandrivorans (Bsal) which infects the skin of salamanders, killing them. This is of course an example of beneficial mutations (from Bsal’s point of view), since Bsal produces more copies of itself the more salamanders it can infect.

Creationist mode:


The discovery of these jumping genes and their role in increasing the virulence of Bsal was made by a team of scientists led by the MRC Centre for Medical Mycology at Exeter University, Devon, UK. Their findings as published, open access, in Proceeding of the National Academy of Science (PNAS).

The Exeter University news release gives the details:
A fungus that infects salamanders contains multiple copies of the same “jumping genes”, scientists have discovered.

Jumping genes, called transposons, can “copy and paste” themselves and impact the organism.

Most organisms have some repeated parts of their DNA, some of which are jumping genes, but this can be harmful – and mechanisms exist to prevent or limit this.

However, the new study – led by the MRC Centre for Medical Mycology at the University of Exeter – finds a possible evolutionary advantage of these jumping genes in a fungus called Batrachochytrium salamandrivorans (Bsal).

Not only did they find different versions of these jumping genes repeated multiple times in Bsal’s genome – but the gene in question appears to have duplicated another group of genes that play a role in how severely it affects infected fire salamanders.

Bsal and related fungal species infect amphibians worldwide, and have been responsible for more than 90 extinctions. Bsal infects the skin of salamanders and newts and causes severe wounds.

It emerged in Asia, where many newts and salamanders have some tolerance, but it has spread to Europe and is causing European salamander populations to decline.

Using new sequencing technologies, we found that Bsal has undergone a genome expansion compared to related species – that is to say, it now has a bigger genome with more genes and also more of these ‘jumping gene’ transposons.

If you think of an organism’s genome as a blueprint, transposons are like having many identical pages, and sometimes, during the process of copying and pasting, other parts of the book are also copied.

It appears that this copying and pasting caused by repetitive jumping gene transposons has also amplified some skin-destroying genes. Having more of these skin-destruction genes allow the fungus to destroy the skin of salamanders more quickly, making it more deadly.

Theresa Wacker, first author.
Medical Research Council Centre for Medical Mycology
University of Exeter, Exeter, UK.

Most organisms have a few jumping gene transposons. In humans, they typically make up less than 1% of the genome, and we have controlling mechanisms to prevent this from rising.

In Bsal, repeated jumping genes make up about 19% of the genome. Transposon jumping genes can interfere with regular gene function and cause problems for the organism – but for Bsal this seems to be outweighed by the advantages.

This kind of gene repetition is probably more widespread in nature than we currently realise.

If, as appears to be the case, it confers an evolutionary advantage for the pathogen by making it more virulent, it’s not clear why this isn’t much more common.

Dr. Rhys A Farrer, lead author.
Medical Research Council Centre for Medical Mycology
University of Exeter, Exeter, UK
The new study found the ability of jumping gene transposons to copy and paste themselves contributed significantly to this expansion. The team are now doing further research.

Senior author Dr Rhys Farrer said repetitive DNA, including jumping genes, is sometimes referred to as “junk” DNA.

The study’s finding shed new light on the evolution of a major amphibian disease, and Dr Farrer called it a “paradigm shift” in terms of identifying repetitive genome content as a driving force behind its pathobiology.
Copyright: © 2023 The authors.
Published by PNAS. Open access. (CC BY 4.0)
The team's findings can be read in the journal PNAS:
Significance

Batrachochytrium salamandrivorans (Bsal) and its closest relative B. dendrobatidis (Bd) are fungal pathogens that threaten amphibians globally. Pathogenicity in vertebrates by species of Batrachochytrium is thought to have emerged from nonpathogenic and saprobic relatives over millions of years through gene expansions of secreted proteolytic enzymes families. Using deep nanopore sequencing and comparative genomics, we discover that Batrachochytrium genomes have undergone a repeat-driven expansion characterized by flanking repetitive elements enriched around pathogenicity genes, genes with signatures of positive selection, and genes upregulated during infection. These genomic features are the hallmarks of two-speed genomes that have to date only been described in plant pathogens. These discoveries shed new light on the evolution of fungal pathogens of vertebrates driving global declines and extinctions.

Abstract

The origins and evolution of virulence in amphibian-infecting chytrids Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal) are largely unknown. Here, we use deep nanopore sequencing of Bsal and comparative genomics against 21 high-quality genome assemblies that span the fungal Chytridiomycota. We discover that Bsal has the most repeat-rich genome of the Chytridiomycota, comprising 40.9% repetitive elements; this genome has expanded to more than 3× the length of its conspecific Bd, with autonomous and fully functional LTR/Gypsy elements contributing significantly to the expansion. The M36 metalloprotease virulence factors are highly expanded (n = 177) in Bsal, most of which (53%) are flanked by transposable elements, suggesting they have a repeat-associated expansion. We find enrichment upstream of M36 metalloprotease genes of three novel repeat families belonging to the repeat superfamily of LINEs that are implicated with gene copy number variations. Additionally, Bsal has a highly compartmentalized genome architecture, with virulence factors enriched in gene-sparse/repeat-rich compartments, while core conserved genes are enriched in gene-rich/repeat-poor compartments. Genes upregulated during infection are primarily found in the gene-sparse/repeat-rich compartment in both Bd and Bsal. Furthermore, genes with signatures of positive selection in Bd are enriched in repeat-rich regions, suggesting these regions are a cradle for the evolution of chytrid pathogenicity. These are the hallmarks of two-speed genome evolution, and this study provides evidence of two-speed genomes in an animal pathogen, shedding light on the evolution of fungal pathogens of vertebrates driving global declines and extinctions.

Of special note for Creationists:
  • If this is intelligent design, the designer can't be regarded as benevolent, since the purpose of the fungus, and then of the modifications the team found, appears to be to make salamanders suffer and die.
  • The mechanism of the mutations is one which biologists already recognise as one of the methods by which information can increase in a genome.
  • This is an example of a beneficial (to the fungus) mutation since, by increasing its virulence, it is increasing the number of copies of the duplicated genes in the genome of the next generation compared to the normal compliment of genes.
  • The scientists are entirely dependent on the Theory of Evolution to explain why this mutation has increased and spread in the species genome. There is no suggestion in their findings that magic creation is a better explanation.
All in all then, a paper that Creationists will wish had never been published and which they are almost certain never mention inside their cult's echo chambers if they want to remain members.

Wednesday, 4 January 2023

Trumpanzee News - Trumpanzees CAN be Nicer People

MAGA insurrectionists
Trumpanzees resorting to violence because they lost the election.
Conspiracy Theorists Are Nicer After Thinking Things Through | Psychology Today

A characteristic of Trumpanzee cultists, is their almost complete dependence on conspiracy theories to sustain their patently absurd belief in Donald Trump as some sort of divinely inspired saviour sent by God to engage with Satanic figures running the 'Deep State'.

These Satanic figures are, of course, because the only important things that happen in the world, happen in America, Democrat politicians, scientists and billionaires such as Bill Gates, led by Hilary Clinton, Barak Obama and assorted cannibalistic paedophiles. The conspiracy Trump was fighting gets ever more lurid, the more preposterous it becomes.

The 'Paedophile Deep State' conspiracy of course involved all the election officials in states where Joe Biden won in 2020, because they helped 'steal' the election from the rightful winner, Donald Trump, and all the judges who refused to overturn the result on the 'spurious' grounds that Trump's advocates could not find any evidence to support their claim, other than Trump's claim that he won really.

Another aspect of this 'Paedophile Deep State' conspiracy is the belief that the COVID-19 pandemic was fake and a pretext for injecting people with mind-controlling vaccines developed by Bill Gates, or as an excuse to stop people going to church, or that wearing face coverings was an attempt at population control because people can't breathe properly with a face covering and die of asphyxia. Of course, government health officials like Anthony Fauci, America's leading epidemiologist, were part of the conspiracy and faked the statistics such as the case numbers and deaths.

The third aspect of Trumpanzeeism is the belief that demands by black people to be treated the same as white people by the police is a conspiracy by political extremists such as anti-fascists [sic], to deprive white Christians of their rightful position as the middle and upper class of a stratified society. A society in which the poor (and Black) only have themselves to blame, welfare is a scam whereby the white middle class is robbed through taxation to subsidise fecklessness and drug dependence, and health care should be preserved for those who can afford to pay for it, the way God intended, in White Christian America.

And we shouldn’t forget the notion that Mexicans are all drug-dealing criminals and rapists who want to destroy America.

But just holding whackadoodle beliefs is itself harmless. What is harmful is the antisocial behaviour that can come from holding them, such as discouraging people from getting vaccinated against a lethal virus, encouraging them to attend super-spreader events where social distancing and wearing face coverings were seen as a disloyal political statement, and such as trying to overthrow a democratic government in a violent insurrection.

Previous research has shown that holders of conspiracy theories are more likely to indulge in criminal activities and other anti-social behaviour and less likely]y to conform to prosocial norms, often regarding laws and social norms as part of the conspiracy.

But there is some hope that at least the more anti-social consequences of holding conspiracy theories, such as those adhered to by Trumpanzees, according to the results of an interesting study by four researchers at the Leibniz-Institut für Wissensmedien, Tübingen, Germany, led by Lotte Plummerer, a PhD candidate.

As described in Psychology Today by Craig Harper Ph.D.:

Friday, 30 December 2022

Unintelligent Designer News - An Enzyme Which Protects Us Against Viruses Also Causes Cancers. Is this Malevolence or Incompetence?

Enzyme That Protects Against Viruses Could Fuel Cancer Evolution | Newsroom | Weill Cornell Medicine
A three-dimensional image of a cancer cell's nucleus obtained by Dr. Faltas and his team shows the APOBEC3G protein (green) inside the nucleus (blue).
In a stunning example of unintelligent design, an enzyme that Creationists have to believe was designed by their putative omniscient designer god to protect us from the viruses it designs to make us sick, also causes cancers. Whether this is evidence of malevolence or incompetence is difficult to say, if you believe the Creationist claims. What it can't in all honesty be presented as is evidence of supreme intelligence and omnibenevolence.

Fortunately, people who understand evolutionary biology don't need to concern themselves with those sorts of questions because they know a mindless, utilitarian natural process like evolution is not a sentient entity and therefore has no intent. Arms races such as that between our immune system and viruses is entirely predictable, as is the example of trade-off between protecting against viral infection and causing cancer. The only test of effectiveness is in the number of descendants that survive to reproduce.

The role of the enzyme, called APOBEC3G, which protects human cells against retroviral attack, in promoting cancer was discovered by a team lead by researchers at Weill Cornell Medicine who used a preclinical model of bladder cancer to investigate the role of the enzyme in promoting the disease and found that it significantly increased the number of mutations in tumour cells, boosting the genetic diversity of bladder tumours, making it harder to treat and hastening mortality.. They have published their findings in the journal Cancer Research, sadly behind a paywall.

The Weill Cornell Medicine news release gives details:

Wednesday, 28 December 2022

Creationsm in Crisis - How A New Plant Species Evolved


Ethereal color variant of mysterious plant is actually a new species | Research at Kobe
Figure 1. Morphological comparison of the aboveground parts of M. kirishimense and M. humile:
(a-c) M. kirishimense, (d-e) M. humile, (f). M. humile f. roseum (color variant of M. humile). The arrowheads indicate spreading sepals.

Photographed by Masayuki Sato (a), Katsumi Iwahori (b), Shuichi Kurogi (c), Shin Terui (d), Kazushige Uemori (e), and Kenji Suetsugu (f).
Giving the lie yet again to Creationists' absurd claim that the Theory of Evolution (TOE) is being increasingly rejected by mainstream scientists and is about to become the first scientific theory to be replaced by a superstition based on magic and an unproven supernatural entity, Bronze Age Creationism, scientists in Japan have discovered that what was thought to be a colour variant of a parasitic plant, is in fact a new species. They have suggested how this new species could have evolved from the parent species.

The new species is the rosy pink form of the parasitic plant known to science as Monotropastrum humile. These plants as found throughout the woods of East and Southeast Asia and have lost their ability to photosynthesise, depending instead on the hyphae of soil fungi which are themselves in a symbiotic relationship with other plants. These soil fungi connect to the roots of other plants and help breakdown organic molecules in the soil into nutrients the plans can use. In return the plants supply the fungi with the sugars they produce in their leaves. Monotropastrum humile however, is a free loader on this system and not only takes the nutrients but also the sugars, while giving nothing in return.

But it's not this parasitic relationship which is under consideration here, but the newly-discovered status of the rosy pink form, which close examination and 20 years of study have shown to be a different species. The Kobe University scientists who identified it as a new species have named it M. kirishimense, after Kirishima, in Kagoshima Prefecture, Japan, where it was first found growing.

From the Kobe University news release:
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