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Researchers from the Hebrew University of Jerusalem have uncovered yet another layer of exquisite molecular sophistication in one of humanity’s most persistent and lethal parasites, Plasmodium falciparum, the chief cause of malignant malaria. Their findings, reported in a recent press release and published in the peer-reviewed Journal of Cell Biology, describe a newly identified regulatory “crown” checkpoint that controls parasite reproduction with remarkable precision.
It is difficult to imagine a discovery more awkward for Intelligent Design creationists, because Plasmodium falciparum is precisely the sort of organism that embodies everything Michael Behe and William Dembski insist cannot arise by evolution. Here is complex specified genetic information, tightly regulated developmental choreography, and interlocking biochemical machinery operating across multiple life stages — the very definition, we are told, of “irreducible complexity”.
Unfortunately for the Discovery Institute, this irreducible complexity does not produce a bird’s wing, a human eye, or some uplifting example of divine craftsmanship. It produces malaria — a parasite responsible for immense suffering and hundreds of thousands of deaths every year, mostly children. If complexity is meant to be a hallmark of intelligent design, then the designer’s portfolio includes some rather grim specialities.
The problem is compounded by the fact that Michael Behe has already made malaria central to his arguments. In The Edge of Evolution, he famously pointed to the parasite’s resistance to anti-malarial drugs as an example of the supposed limits of Darwinian evolution, claiming that multiple coordinated mutations were beyond the reach of natural selection. Yet malaria has since become one of the clearest demonstrations that evolution not only occurs, but does so rapidly and repeatedly, exploiting enormous population sizes and intense selection pressures to produce exactly the adaptations Behe claimed were improbable.
As Kenneth Miller pointed out, Behe's mathematical sleight of hand was to assume resistance had to evolve as a single event in a single cell, not across a large population over time - a fallacy of which any good microbiologists should have been aware.
This newly described “crown” stage is simply the latest reminder that biological complexity is not evidence of supernatural design. Evolution predicts complexity wherever it confers survival advantage — including in parasites, pathogens, and diseases. The only real surprise is that creationists continue to present complexity as a theological virtue, when nature so often deploys it in the service of exploitation rather than benevolence.
As ever, none of this will deter creationists from repeating their familiar articles of faith. Faced with an organism whose life cycle resembles a biochemical symphony — regulated checkpoints, specialised invasion machinery, host-cell remodelling, immune evasion, and reproductive stages split between mosquito and human — they will insist that this is not evidence for evolution but evidence against it. The argument, such as it is, runs that complexity must have been present from the start, because it could not have arisen gradually.
But this is simply the old “irreducible complexity” claim in a new disguise: the assertion that because creationists personally cannot imagine intermediate stages, no such stages could have existed. Science, of course, is not obliged to conform to the limits of anyone’s imagination. Evolution does not require that complex systems appear in a single leap. It proceeds by modification of what already exists — co-option, duplication, repurposing, and incremental refinement over deep time — producing the layered complexity we observe today.
Another common retreat is the insistence that this is merely “microevolution”, the trivial shuffling of genes within some mythical created “kind”. Yet Plasmodium falciparum is not merely adjusting the colour of its spots. It is evolving novel biochemical strategies, repeatedly acquiring drug resistance, fine-tuning developmental regulation, and exploiting host environments with extraordinary efficiency. If this is “only microevolution”, then the term has been drained of all meaning.







































