Showing posts with label Microbiology. Show all posts
Showing posts with label Microbiology. Show all posts

Monday, 10 November 2025

Refuting Creationism - Microbes That Create Life From Non-Life

Mud volcano

Fig. 9: Schematic of microbial succession and biogeochemical processes in serpentinite mud at the Mariana forearc.
This schematic depicts lipid biomarker transitions from pelagic sediment communities to extremophiles adapted to high pH and redox conditions in serpentinite mud. The Mariana forearc biosphere is fueled by alkaline serpentinization fluids enriched in H2, CH4, DIC, and organic acids, sustaining specialized microbial communities. Lipid and stable carbon isotope data reveal a shift from relict methanogenic archaea, likely engaged in hydrogenotrophic methanogenesis, to a later ANME-SRB community mediating anaerobic oxidation of methane (AOM). Changes in substrate availability likely drove this transition. Distinct lipid signatures, including unsaturated diethers, acyclic GDGTs, and ether-based glycolipids, highlight adaptations to pH stress, phosphate limitation, and fluctuating redox conditions. The presence of in-situ branched GDGTs suggests previously uncharacterized bacterial communities persisting in these ultra-oligotrophic conditions. The Mariana forearc serpentinite biosphere, shaped by episodic fluid flow and substrate shifts, provides insights into deep-sea subsurface habitability. DIC = dissolved inorganic carbon, ANME anaerobic methanotrophic archaea, SRB sulfate-reducing bacteria, AOM anaerobic oxidation of methane, GDGT glycerol dialkyl glycerol tetraether.


Fats provide clues to life at its limits in the deep sea

Researchers at MARUM – Bremen University’s Centre for Marine Environmental Sciences – have made a discovery, just published open access in the journal Communications Earth & Environment, which, properly understood, should make depressing reading for creationists.

They have found living organisms both on and within the ocean floor, surviving in conditions where normal life would be impossible. These microorganisms inhabit mud volcanoes with a pH of 14, metabolising hydrogen and carbon to form methane by drawing energy from minerals in the surrounding rock. In other words, they live entirely without oxygen and with almost no organic matter, synthesising all they need from inorganic sources.

Informed creationists will recognise that these organisms directly refute their frequent assertion that life cannot arise from non-life — because producing life from non-life is precisely what these microorganisms are doing.

This also contradicts the biblical claim that all living things were created for the benefit of humans, since there is no conceivable way these organisms could serve any human purpose. Of course, to be fair, the authors of the Bible were completely ignorant of microorganisms, deep-ocean mud volcanoes, and chemosynthetic metabolism. They could only attempt to explain the larger creatures that lived in the limited region around their homes in the Canaanite hills.

And, as any informed creationist should also understand, these are exactly the sort of extreme conditions that biologists believe may have fostered the emergence of the earliest living organisms during the origin of life on Earth — once again undermining any claim that abiogenesis is impossible.

Background^ Chemosynthetic Extremophiles. Chemosynthetic extremophiles are microorganisms that survive in environments too hostile for most known life. Instead of relying on sunlight for energy (as photosynthetic organisms do), they extract energy from chemical reactions involving inorganic compounds such as hydrogen, methane, ammonia, or sulphides.

These organisms thrive in extreme conditions — high pressure, intense heat or cold, high salinity, or extreme acidity or alkalinity — where oxygen and organic nutrients are scarce or absent. They are commonly found around deep-sea hydrothermal vents, cold seeps, and mud volcanoes, as well as in acidic mines and alkaline lakes.

Chemosynthesis typically involves oxidising inorganic molecules (e.g. hydrogen sulphide, hydrogen, or iron) to obtain energy, which is then used to convert carbon dioxide or methane into organic compounds. This allows entire ecosystems — such as those around black smokers on the ocean floor — to exist entirely independent of sunlight.

These extremophiles are of major interest to biologists and astrobiologists because they demonstrate that life can originate and persist in conditions once thought uninhabitable. Their existence supports hypotheses that early life on Earth, and potentially elsewhere in the universe, may have begun in similar environments where energy was derived chemically rather than from sunlight.
The research is explained in a Universität Bremen news item.
Fats provide clues to life at its limits in the deep sea
Researchers use lipid biomarkers to reveal survival strategies in extreme ecosystems

Diverse life forms exist on and within the ocean floor. These primarily consist of microbes, tiny organisms that can cope with extreme environmental conditions. These include high pressures and salinities, as well as extreme pH values and a limited supply of nutrients. A team of researchers has now been able to detect microbial life in two newly discovered mud volcanoes with very high pH values. Their findings have been published in the professional journal Communications Earth & Environment.

Blue serpentinite mud from a newly discovered mud volcano in a gravity core. The samples have been studied by a team in order to decipher the survival strategies of microorganisms.
Photo: SO292/2 Expedition Science Party
In their study, first author Palash Kumawat of the Geosciences Department at the University of Bremen and his colleagues used lipid biomarker analyses to decipher the survival strategies of the microbes in this harsh ecosystem. The high pH value of 12 here is especially challenging for deep-sea life; This is one of the highest known value so far in ecosystems. In order to detect life at all, the researchers had to resort to special methods of trace analysis. In this situation, the detection of DNA can be ineffectual where there is a low number of living cells.

But we were able to detect fats. With the help of these biomarkers we were able to obtain insights into the survival strategies of methane- and sulfate-metabolizing microbes in this extreme environment.

Palash Kumawat, first author
Faculty of Geosciences
University of Bremen
Bremen, Germany.

Microbial communities metabolize carbon in the deep sea and thereby contribute to the global carbon cycle. However, the communities that the team describe in the publication draws its energy from minerals within rocks and gases such as carbon dioxide and hydrogen to produce methane, for example, an important greenhouse gas. These processes initially take place independently of the ocean above. The lipids also provide clues to the age of the microorganisms. If the cellular biomolecules are intact, they represent a living or recently dead community. If they are not intact, they are geomolecules, which means that they are fossil communities from the past. According to Kumawat, the combination of isotopes and the lipid biomarkers indicates that multiple microbial communities now live in this inhospitable habitat and have lived there in the past.

This distinction helps us when working in areas with extremely low biomass and nutrient deficiency.

Palash Kumawat.

Dr. Florence Schubotz, organic geochemist at MARUM – Center for Marine Environmental Sciences at the University of Bremen and co-author of the study, adds:

What is fascinating about these findings is that life under these extreme conditions, such as high pH and low organic carbon concentrations is even possible. Until now, the presence of methane-producing microorganisms in this system has been presumed, but could not be directly confirmed. Furthermore, it is simply exciting to obtain insights into such a microbial habitat because we suspect that primordial life could have originated at precisely such sites.

Dr. Florence Schubotz, co-author
MARUM – Center for Marine Environmental Sciences
University of Bremen
Bremen, Germany.

The samples for the study come from a sediment core that was retrieved by the Research Vessel Sonne in 2022 during Expedition SO 292/2. Not only were the scientists able to discover the previously unknown mud volcanoes of the Mariana forearc during this cruise, but also to sample them.
The samples were obtained as part of the Cluster of Excellence “The Ocean Floor – Earth's Uncharted Interface.” Palash Kumawat and his colleagues are now planning to cultivate organisms in an incubator to find out more about their nutrient preferences in inhospitable environments.

Publication:
Abstract
Present-day serpentinization systems, such as that at the Mariana forearc, are prominent sources of reduced volatiles, including molecular hydrogen (H2) and methane (CH4), and are considered analogs for chemosynthetic ecosystems on early Earth. However, seepage of serpentinization fluids through mud volcanoes at the Mariana forearc seafloor is defined by high pH, and nutrient scarcity, creating challenging conditions for microbial life. We present geochemical and lipid biomarker evidence for a subsurface biosphere shaped by episodic substrate availability, highlighting microbial persistence across steep geochemical gradients within serpentinite mud. Light stable carbon isotope compositions from diagnostic lipids reveal a temporal shift from hydrogenotrophic methanogenesis to sulfate-dependent anaerobic methane oxidation. Membrane adaptations, including unsaturated diether, acyclic and branched tetraether, and ether-based isoprenoidal and non-isoprenoidal glycosidic lipids, reflect microbial strategies for coping with this extreme environment. Our findings establish the Mariana forearc as a unique serpentinite-hosted biosphere, where life operates at the fringes of habitability.

Introduction
The subseafloor biosphere is estimated to harbor up to 15% of the global biomass1. Recent advances in deep biosphere research have improved our understanding of the distribution and diversity of microbial life in the rocky oceanic crust, especially around hydrothermal vents2,3. This subseafloor biosphere has to adapt to limited carbon and nutrient availability, accompanied by harsh environmental conditions such as high temperature and pressure, elevated salinity, and/or extreme pH levels4. Serpentinization of mantle rocks by seawater can generate high levels of H25,6 that, in turn, drives the abiotic reduction of carbon to form CH4 and other organic compounds7, which can be oxidized by chemosynthetic organisms8,9,10, forming the foundation for a serpentinite biosphere11. The type locality for such a serpentinite biosphere is the Lost City hydrothermal vent field near the Mid-Atlantic Ridge, where hydrothermal fluids fuel microbial communities in active and inactive vent structures12. Methanogenic archaea there are found in active brucite-calcite vents, whereas older carbonate chimneys host a syntropic consortium of anaerobic methanotrophic archaea (ANME) and sulfate-reducing bacteria (SRB) that perform the anaerobic oxidation of methane (AOM)13,14.

The process of serpentinization takes place in a range of geotectonic settings, including rifted continental margins, mid-oceanic ridges, transform faults, and convergent margins. Among the latter, the forearc of the Mariana subduction system is of particular interest because it provides access to serpentinization products from within an active subduction zone. There, dewatering of the subducting Pacific Plate leads to serpentinization of the mantle wedge of the overriding Philippine Sea Plate. Faults reaching 10–25 km deep into the forearc allow serpentinite, together with fluids derived from the subducting slab, to buoyantly rise and form large ‘serpentinite mud volcanoes’ on the seafloor15,16 (Fig. 1a, c). Fluids venting from the mud volcanoes are cold (<3.5 °C), hyperalkaline (pH up to 12.6), and enriched in H2 and CH4 (both up to ~1 mM)17,18 and slab-derived sulfate (SO42−; up to 28 mM)19. These fluids are also enriched in short-chain organic acids like acetate (0.04 mM) and formate (0.1 mM), contributing ~20–30% of the dissolved organic carbon (DOC)20, and in methanol (0.03 mM)20,21. The δ13C of CH4 (−37‰ to 2‰), acetate (−8‰), formate (4.8‰) and methanol (2.3‰) point to their abiotic formation17,21. While these serpentinization fluids sustain chemosynthetic life at the seafloor22,23, the functioning and extent of the chemosynthetic microbial biosphere below the seafloor remains largely unknown. Cell counts in the serpentinite mud are variable, but overall low (101 to 106 cells cm−3)20,24, presumably because of the high pH and intermittent fluid seepage13,16. Extremophilic archaea are believed to perform AOM as inferred from the detection of phospholipid-derived diphytanyl diethers and reduced sulfur species in the formation fluids18. Metabolic transcripts for denitrification and AOM were interpreted as evidence for nitrate-dependent AOM within the serpentinite mud volcanoes24. Although AOM is considered thermodynamically favorable here19,25, direct evidence for AOM and its associated microorganisms is still lacking. Methanogenesis is a common metabolic strategy in serpentinization systems13, but since CH4 formation at the Mariana forearc is dominantly abiotic, the extent of microbial methanogenesis remains uncharacterized.
Fig. 1: Study area and geological context of serpentinite mud volcanism in the Mariana subduction system.
a Bathymetry map of the Mariana subduction system showing the incoming Pacific Plate, the overriding Philippine Sea Plate, the Mariana Trench, and a subset of the known serpentinite mud volcanoes on the forearc seafloor. Stars mark the locations of the Pacman and Subetbia mud volcanoes investigated in this study. Bathymetry from GEBCO Compilation Group125. b Bathymetry map showing the Pacman mud volcano and the location of gravity core GeoB24917-1 retrieved during expedition SO292/2. Bathymetric data collected during expedition SO292/226. c Schematic of serpentinite mud volcano formation, following serpentinization of the mantle wedge by slab-derived fluids, formation of H2 and CH4, and the rise of serpentinite mud and fluids through deep-seated faults towards the seafloor.

This study documents AOM coupled to sulfate reduction as a key metabolic process in the Mariana forearc, indicating the importance of methane cycling for the indigenous microbial community. Our findings also provide evidence of relict methanogenesis in the serpentinite mud, where its temporal distribution is possibly controlled by variable substrate availability. We present a comprehensive lipid biomarker and isotopic record from the Pacman and Subetbia mud volcanoes, providing insights into the habitability and survival strategies of extremophilic chemosynthetic life in this serpentinite biosphere.

Kumawat, P., Albers, E., Bach, W. et al.
Biomarker evidence of a serpentinite chemosynthetic biosphere at the Mariana forearc. Commun Earth Environ 6, 659 (2025). https://doi.org/10.1038/s43247-025-02667-6

Copyright: © 2025 The authors.
Published by Springer Nature Ltd. Open access.
Reprinted under a Creative Commons Attribution 4.0 International license (CC BY 4.0)
Creationists often insist that “life cannot come from non-life,” claiming that the origin of life through natural processes — abiogenesis — is impossible. Yet these microorganisms thriving deep beneath the ocean floor undermine that argument completely. They demonstrate that life does not require sunlight, oxygen, or organic nutrients. Instead, it can sustain itself entirely through chemical reactions involving inorganic matter, precisely the kind of chemistry that would have been available on the early Earth long before photosynthesis or complex ecosystems evolved.

These microbes survive by harnessing energy from the oxidation of minerals and gases such as hydrogen and carbon, producing methane as a by-product. In doing so, they show that biological systems can indeed emerge and persist using nothing more than inorganic chemistry and environmental energy sources. If life can continue this way today — in conditions strikingly similar to those thought to exist on the early Earth — then it is perfectly reasonable to infer that the same processes could once have given rise to life itself.

Creationists’ claim that life from non-life violates natural law is based on a false analogy with modern life, which relies on pre-existing organic systems. But these extremophiles illustrate that the boundary between “non-living” chemistry and “living” biochemistry is not a rigid wall — it is a continuum. The metabolic reactions that sustain these organisms are direct chemical extensions of the mineral and geochemical reactions occurring in their surroundings. Life in such places does not appear magically; it emerges naturally from the physical and chemical conditions of its environment.

Far from being a problem for evolutionary science, discoveries like this one strengthen the case for a natural origin of life. They show that even today, the chemistry of life and the chemistry of rocks remain intimately connected. To deny that such chemistry could, under the right conditions, cross the threshold into life is to deny the very evidence creationists claim to seek — evidence that life can, and demonstrably does, arise from the non-living world through the workings of natural law.

Sadly, the same creationists who continue to parrot the 'no life from non-life' fallacy won't have understood a word of that and will continue to make proven false claims.


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Friday, 26 September 2025

Creationism Refuted - How Co-Evolution Gave Us Sleep - Courtesy of Our Gut Microbiome


Key to the riddle of sleep may be linked to bacteria | WSU Insider | Washington State University

For an astonishing example of co-evolution — not just involving two organisms but a whole host that have co-evolved over millions of years — you need look no further than your own body, as a paper in *Frontiers in Neuroscience* by Erika L. English and James M. Krueger of Washington State University (WSU) shows. It reports the finding that sleep may be a co-evolved condition in which gut micro-organisms play a central role.

The researchers showed that, in mice, there is a close relationship between sleep patterns and the cyclical presence in the brain of a substance known as peptidoglycan (PG), normally found in the mesh-like walls of gut bacteria. Although co-evolutionary relationships are a well-established concept in evolutionary biology, this example illustrates just how intimate such relationships can become — to the point where it is difficult to say, in biological terms, which organism is the “product” of the other. To what extent are we the product of our gut bacteria, and to what extent are they the product of us?

Of course, creationism has nothing to say about this kind of co-evolution because the Bible is silent on the matter of micro-organisms or evolution. It contains nothing that wasn’t visible to its Bronze Age authors with the naked eye, or that lived outside the narrow confines of their limited experience. It was written by people with no appreciation of the history of life on Earth or of how it has been shaped by environmental change and ecological balances over deep time.

Saturday, 13 September 2025

Malevolent Design - How Our Gut Microbiome is 'Designed' to Destroy Our Kidneys - Malevolence or Evolution?


Kidney fibrosis linked to molecule made by gut bacteria – News Bureau

Mostly, our gut microbes are beneficial or at least neutral because we have co-evolved and reached an accommodation. One benefit we derive from their presence is that they make life difficult for potentially harmful organisms, if only by monopolising the available resources and occupying the niches in our gut.

There is a downside, of course, as in any evolved system, which is inevitably a compromise and can tip over into pathology under certain circumstances. But overall, because the disadvantages are more than compensated for by the benefits, the system has evolved and been maintained.

However, a newly discovered downside is that a Staphylococcus species may be implicated in one of the serious complications of diabetes mellitus (DM) — kidney fibrosis and ultimately kidney failure. The discovery was made by researchers at the University of Illinois Urbana-Champaign and Mie University in Japan, co-led by Professor Isaac Cann of Illinois and Professor Esteban Gabazza of Mie University. The bacterium is believed to produce corisin — a small peptide — which is found at high levels in patients with diabetic kidney fibrosis. The researchers have just published their findings, open access, in Nature Communications.

For creationists, this sort of discovery is always a problem, one they normally ignore or blame on “Eve’s sin,” revealing ID creationism for what it is — Bible literalism in a lab coat — which must retreat into mystical theology when faced with problems ID cannot address. Yet creationists also claim that their omniscient creator god is personally responsible for the design of organisms such as Staphylococcus. That would mean it knowingly endowed Staphylococcus with the genes to make corisin, along with all the harmful consequences.

Taking William A. Dembski’s “complex specified genetic information,” which supposedly produces a specific outcome, at face value, the staphylococcal genes are equally “proof” of intelligent design. And so we end up with an unresolved paradox for ID creationism: “complex specified” genes that do us harm, standing as evidence of malevolent design.

Sunday, 7 September 2025

Refuting Creationism - Scientists Recover Ancient Bacterial DNA - On Million-Year-Old Mammoth Teeth

Steppe Mammoths
AI-generated image (ChatGPT 5)

Ancient mammoth remains yield the world's oldest host-associated bacterial DNA - Stockholm University

Parasite–host relationships are a nightmare for creationists. Their usual escape hatch is “The Fall”, but that undermines the Discovery Institute’s claim that intelligent design is science rather than Bible-literalist dogma in a lab coat. It also raises the obvious question: if parasites only appeared 6,000–10,000 years ago, how did they spread so quickly—and why do we find fossil evidence of parasitism millions of years old?

Creationists cope by dismissing science as a conspiracy, waving away radiometric dating, or pushing myths such as dinosaur fossils being “carbon-dated” [sic] to a few thousand years old. So creationism persists, despite the vast amount of evidence against it, by a combination of wilful ignorance, disinformation and a lack of critical thinking skills.

Now creationists must also ignore new research from Stockholm University, where scientists isolated bacterial DNA from the teeth of woolly and steppe mammoths. They showed these bacteria evolved into the ancestors of those infecting modern elephants—evidence of parasites a million years before “Creation Week”, and of co-evolution continuing right up to today’s elephants, the descendants of those mammoths.

Incidentally, neither mammoths nor modern elephants are mentioned in the Bible, reflecting the parochial ignorance of its authors - a fact often overlooked in depictions of animals boarding Noah's Ark, which usually includes a pair of elephants!

Saturday, 6 September 2025

Creationism Refuted - How Micro-oranisms Acquire New Genetic Information - Millions of Times A Day

AI generated image
ChatGPT 5

Researchers Quantify Rate of Essential Evolutionary Process - Bigelow Laboratory for Ocean Sciences

Researchers at Bigelow Laboratory for Ocean Sciences (East Boothbay, Maine, USA) have recently quantified a remarkable evolutionary process: a typical marine microorganism acquires and retains approximately 13% of its genes per million years through horizontal (lateral) gene transfer. This rate corresponds to roughly 250 genes exchanged and retained per litre of seawater each day

These transferred genes include those that provide either a selective advantage or are sufficiently neutral to persist via genetic drift—both well-established mechanisms of evolutionary change.

Some creationist arguments misapply Shannon Information Theory, claiming that gaining new genetic information violates the laws of thermodynamics. However, such arguments disregard key biological realities: cells are open systems capable of energy and material exchange; genome duplication and horizontal transfer are well-documented evolutionary processes; and substituting one nucleic acid for another does not create matter ex nihilo - facts of which any qualified biological scientists should be aware.

Furthermore, the successful retention and spread of horizontally acquired genes within microbial genomes provide clear, empirical evidence of Darwinian evolution in action. Although Charles Darwin formulated his theory without the concept of genes — speaking instead of 'heritable traits' — his mechanism of natural selection precisely explains how heritable variations can spread through populations over time.

This study also highlights that microorganisms can evolve not only through mutation and selection but also by acquiring pre-adapted genes from their environment, often from distantly related organisms. Consequently, these newly acquired genes can propagate rapidly within the recipient lineage.

The findings further challenge traditional microbial taxonomy, blurring species boundaries at the genetic level: horizontally transferred genes may function just as effectively in their new hosts as they did in their original genomes, thanks to the universality of underlying molecular machinery (e.g., replication and translation systems).

Tuesday, 5 August 2025

Creationism Refuted - The Subterranean Microbes That Make Creationists Sick


Karen Lloyd
Buried Alive: The Secret Life of Deep Earth Microbes

What if we could peer back through deep time and see what single-celled organisms looked like—not just thousands, but hundreds of millions of years ago—and compare them to their living descendants? It would be a revelation for science… and a nightmare for creationists.

That’s precisely what geobiologist Karen Lloyd and her team at the University of Southern California (USC) are uncovering. They study microorganisms that have made an incredible journey: born in the depths of the ocean, slowly buried under a relentless rain of sediment, and then carried by plate tectonics into the deep Earth, where subduction dragged them beneath continental crust. There, cut off from oxygen and sunlight, they survived for millions of years in a slow-motion existence, drawing nutrients from the surrounding rock. Their metabolic rates became so low they could no longer replicate, yet they endured by “breathing”—in the biochemical sense—through redox reactions, extracting energy from electrons provided by whatever electron donors the rocks could supply. Some have even evolved the ability to “breathe” carbon dioxide, something unknown among terrestrial life.

These organisms’ existence is a direct challenge to creationist dogma—not only because they have persisted for timescales far beyond the Bible’s allowance, but because they reveal how even apparently simple single-celled organisms can diverge and adapt over geological epochs. Environmental pressures have driven them into extraordinary evolutionary niches, each defined by what they have learned to “breathe.” Moreover, they exist in environments in which life as we know it couldn't survive, yet creationists insist that Earth was intelligently created, perfect for life, which begs the question, which life? The life that breathes using arsenic, lives for millions of years deep underground with almost no metabolic activity and survive in the heat and acidity of volcanic hot springs, or life the breathes oxygen and needs a regular supply of water and a narrow range of ambient temperatures in which to survive without special equipment?

Sunday, 22 June 2025

Refuting Creationism - How Living Organism's Survived - 700 Million Years Before 'Creation Week'

Researchers Ian Hawes of the University of Waikato and Marc Schallenberg of the University of Otago measure the physicochemical conditions of a meltwater pond.
Credit: Roger Summons

Pustular microbial mat section such as could have existend in small melt-water ponds.
When Earth iced over, early life may have sheltered in meltwater ponds | MIT News | Massachusetts Institute of Technology

Only by systematically ignoring geological and archaeological evidence can creationists continue to delude themselves into believing that Earth is just a few thousand years old and was perfectly created by an anthropophilic god especially for humans – its supposed “special creation.”

The evidence, however, paints a radically different picture from that childish superstition. Not only was Earth clearly not perfectly created for humans, it wasn’t perfectly created for any life form. And it is far older than creationists assert. In truth, around 600 million years ago, Earth was such a hostile place for life that it was entirely covered in ice. The polar ice sheets had extended until they met at the equator. These “Snowball Earth” conditions led to a mass extinction so severe that it remains something of a mystery how any life survived – especially complex eukaryotic cells.

Now, a multinational team of researchers led by scientists from the Massachusetts Institute of Technology (MIT) has found evidence that early life could have survived in small pools of surface meltwater. They reached this conclusion after studying similar meltwater pools on the McMurdo Ice Shelf in Antarctica. What they found not only showed that single-celled eukaryotes can survive in such conditions, but also revealed that the population of prokaryotes varies according to local environmental conditions

These meltwater pools act as microcosms of diverse environments and demonstrate how local factors shape the distribution of different species – exactly as predicted by the Theory of Evolution. Had the conditions been perfect as creationists insist, there could be no variation in the populations in these pools. Variation only arises because the species need to adapt to different conditions - something that would never be needed in perfectly designed conditions.

The team has just published their findings, open access, in the journal Nature Communications.

Sunday, 6 April 2025

Refuting Creationsm - Evolution By Loss of Genes, Horizontal Gene Transfer And Gene Duplication



Nitzschia sing1 lives on the alginate in the cell walls of decaying brown algae.
A borrowed bacterial gene allowed some marine diatoms to live on a seaweed diet | PRESS-NEWS.org

A fundamental axiom of creationism is the claim that any loss of genetic information is invariably detrimental—so much so that any mutation resulting in such a loss would be fatal and could therefore play no role in evolution. A second axiom asserts that new genetic information cannot arise naturally and must instead be supplied by a supernatural intelligent designer.

Both of these assertions are demonstrably false. Nevertheless, they continue to feature in creationist apologetics, relying on the audience's ignorance and incredulity to pass as justification for belief in an intelligent creator.

To add further difficulty for creationist claims, scientists have now identified a marine diatom, Nitzschia sing1, that has not only lost the genes and organelles required for photosynthesis — present in its photosynthetic relatives — but has also adapted successfully without them. It achieved this by acquiring new genetic information through horizontal gene transfer from a marine bacterium. The transferred gene subsequently underwent extensive duplication and diversification into three gene families, each with complementary functions. Together, these 91 versions of the acquired gene enable N. sing1 to metabolise alginate, a carbohydrate found in the cell walls of brown algae such as kelp.

Wednesday, 27 November 2024

Mallevolent Design - How Salmonella Sneaks Past Our Defences To Make Us Sick


Intestinal lumen
New study shows how salmonella tricks gut defenses to cause infection

There is a simple paradox at the heart of creationism that I have never even seen an attempt to resolve. It all comes from two beliefs: there is only one designer god capable of designing living organisms and that designer god designed us complete with our immune system with which we can attempt to resist attack by pathogens, and that pathogens are not the work of this design, but are the result of 'genetic entropy' and 'devolution' since Adam & Eve let 'sin' into the world. The fact that Michael J. Behe, who invented that excuse, has let slip that ID Creationism is Bible literalism in a lab coat seems to be lost on his followers who still dutifully insist that it is a scientific alternative to evolution and should be taught in school science class (presumably now with the tale of Adam & Eve taught as real history and 'sin' as a real force in science).

The paradox is, did the designer god give Adam & Eve an immune system, or did it design an upgrade when 'sin' allowed pathogens to exist? If the former, it was anticipating and planning for the so-called 'fall'; if the latter, it lacked foresight so is not omniscient.

But however creationists resolve this paradox they still have to explain why the 'intelligently designed' immune system doesn't work very well and why whatever is designing pathogens seems to be able to overcome it.

The nonsense about 'sin', 'the fall', etc., is trivially easy to refute because any improvement in a parasite's ability to parasitise its host can't possibly be regarded as a devolution from some assumed initial perfection because an improvement can't be worse that what it's an improvement on. The whole nonsense of 'devolution' is biological gobbledygook, intelligently designed to appeal to scientifically illiterate simpletons who want to fit the Bible superstition somewhere in the reasoning without bothering too much about the logic or the biology.

So, the paradox boils down to why an intelligent designer would be having an arms race with itself so the parasites it creates can continue to parasitise the victims it creates complete with their immune system it created to stop them. Creationists normally flee in terror at the mere mention of arms races, which is why you'll never see them discussed in the cult literature apart from where pathogens are waved aside as 'caused by sin', blah, blah, blah...
So, it would be refreshing indeed to see a genuine attempt by an intelligent design creationist try to give some rational explanation, and hopefully without giving away the fact that ID creationism is merely Christian fundamentalism in disguise, for the discovery by a new UC Davis Health study that shows how the Salmonella bacteria, a major cause of food poisoning, can invade the gut even when protective bacteria are present.

As an added embarrassment for creationists, Salmonella is closely related to Escherichia coli (E.coli) that they usually cite Michael J. Behe as 'proving' it must have been designed by their god because its flagellum is 'irreducibly complex'.

First a little AI background information about Salmonella, where it came from and what it does to us:

Tuesday, 26 November 2024

Common Ancestry - Ancient Choanoflagellates Genes Used To Make A Mouse


Choanoflagellates, singly and as a colony.
Scientists recreate mouse from gene older than animal life - Queen Mary University of London

If there is one thing designed to get creationists chanting 'Common Designer!' it's evidence of the same gene doing the same thing in lots of different organisms, no matter how distantly related they are.

But when that gene is needed because of a basic design blunder long ago in the evolution of multicellular organisms, that chant looks increasingly forlorn.

For example, scientists have just shown how SOX and POU genes isolated from a single-celled choanoflagellate can be used to convert a mouse cell to function as the stem cell to clone another mouse. The reason this works is because something needs to reset the epigenetic setting in specialised cells. In a multicellular organism like a mouse, this effectively means any cell produced after the first few cell divisions of the fertilised zygote.

But why would a single-celled organism like a choanoflagellate need to do that? The answer it that epigenetics originally evolved to make an organism more able to respond to environmental changes and stresses.

Friday, 8 November 2024

Refuting Creationism - How Eggs Evolved Hundred of Millions of Years Before Chickens


Chromosphaera perkinsii resembles the early stages of animal embryo development during its multicellular life stage
DudinLab
The egg or the chicken? An ancient unicellular says egg! - Medias - UNIGE

Scientists believe they may have cracked the chicken and egg 'problem' that creationists have been fooled into thinking is a killer problem for the Theory of Evolution. With their child-like understanding of evolution, creationists can't imagine how species emerge over time from earlier species by a process of evolution and think that their mythical magic creation without ancestors is actually what happens, or at least what evolutionary biologists think happens. So, they imagine explaining how the first chicken hatched from the first egg before there was a chicken to lay it, is an insurmountable problem.

In fact, of course there never was a first chicken just as there never was a first human, and eggs are simply a phase in the life cycle of, in this case, chickens, so hens' eggs are chickens just as much so as adult hens are. The ancestral species that the Southeast Asian jungle fowl evolved from had been laying eggs ever since they diverged from the egg-laying avian dinosaurs that had evolved from the egg-laying theropod dinosaurs, etc, etc, back to the egg-laying tunicates and chordates in the Cambrian and their egg-laying ancestors...

Saturday, 12 October 2024

Malevolent Design - How Chlamydia Is 'Designed' to Cause Maximum Sufferring.


Schematic representation of how a C. pneumoniae cell infects a human cell. The bacterium injects the protein SemD (green) into the cell, which activates the cell protein N-WASP, which in turn initiates vesicle formation.
Credit: HHU/Fabienne Kocher.
Universität Düsseldorf: Original or copy: How Chlamydia manipulate the host cell

The problem of parasites for creationists is one that, despite the best efforts of apologists like Michael J Behe of the Deception Institute, just won't go away.

Sadly, Behe shot himself in the foot with his original claim to have proven 'intelligent [sic] design in living organisms with his choice of the bacterial flagellum in E. coli, where he persuaded his willing audience that these nasty little pathogens had been intelligently designed - and by unspoken assumption, designed by the locally-popular god.

Now creationists wave his 'proof' of design as evidence for their creator god because only their god is capable of creating living organisms.

But, with characteristic double-think, creationists also argue that their god is omnibenevolent, so something else must have created parasites like E. coli, and, courtesy again of Michael J. Behe, they cite 'Sin' causing 'genetic entropy' and the absurd idea of 'devolution' this supposedly causes, as the cause of parasites and pathogens (but not the bacterial flagellum, obviously!).

The problem with that notion is that they need to do their double-think trick one more time and believe that a trait with improves a pathogens ability to live and reproduce in its host makes it somehow less perfect that one without that trait. So, in the creationist's world, an improvement is a move away from perfection!

But, with a cult that appears to believe learning is a move away from the 'perfection' of pristine ignorance (from whence comes expertise in all aspects of science), that's probably not too difficult a feat of mental gymnastics for a creationist to perform.

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