
Top left: The nuclei of human cells appear in blue. The green signal indicates the presence of a dengue virus protein.
Top right: The nuclei of human cells appear in teal. The magenta signal indicates the presence of a dengue virus protein.
Bottom left: The nuclei of human cells appear in grey. The red signal indicates the presence of a dengue virus protein.
Bottom right: The nuclei of mosquito cells appear in blue. The red and green signal indicates the presence of two dengue virus proteins.
Today it's the turn of researchers at Oklahoma's Stowers Institute for Medical Research to expose the brilliance of creationism's divine malevolence in the way it's designed the Dengue virus to enable it to spread out of the tropics and infect more people. Currently, according to the World Health Oragnisation, the mosquito-borne virus, infects around 400 million people a year and there is no cure.
The Stowers Institute team led by Predoctoral Researcher Luciana Castellano in the lab of Associate Investigator Ariel Bazzini, Ph.D., has discovered how it, and hundreds of other viruses, replicate in their hosts.
Creationism't intelligent designer, for those who believe in magic, uses it's tried and tested mosquito delivery system, especially the Aedes eagypti mosquito which it used so successfully to spread the Zika virus to cause microcephaly in children.
The sneaky trick it used to get past the immune system it allegedly designed to protect us from things like its viruses, is breathtaking in its simplicity. In order to replicate inside a host cell, the virus needs some specific protein enzymes. It has the RNA code for these enzymes, but the problem is, the host's immune system would recognise those as foreign and launch an attack, so the virus uses the hosts enzymes. Proteins are coded for with a three-nucleotide code, one for each amino acid in the chain. However, the same amino acid can be coded for by several different triplet codes, some of which are more efficient than others. To ensure the cell makes its own enzymes for the virus, the virus uses less efficient codons in its own RNA!
This way, the virus tricks the cell into cooperating in its own destruction.
Neat, eh?
It's a classic example of how an apparently deleterious mutation works in favour of a parasite, and something creationists will find impossible to explain away with the biologically nonsensical 'genetic entropy' causing 'devolution' because the mutation was undoubtedly evolutionary, enabling the dengue virus (DENV) to produce very many more copies of itself than before, and something better can't be less perfect than the original.